Efficacy of PBTZ169 and pretomanid against Mycobacterium avium, Mycobacterium abscessus, Mycobacterium chelonae, and Mycobacterium fortuitum in BALB/c mice models [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 ObjectivesWe aimed to evaluate the activity of PBTZ169 and pretomanid against non-tuberculous mycobacteriosis (NTM) in vitro and in vivo.MethodsThe minimum inhibitory concentrations (MICs) of 11 antibiotics, against slow-growing mycobacteria (SGMs) and ...
Luyao Zheng +9 more
doaj +3 more sources
A Rare Case of Osteomyelitis of an Ankle Caused by Mycobacterium chelonae [PDF]
Antibiotics, 2023 Mycobacterium chelonae, a rapidly growing nontuberculous mycobacterium, is usually described as a causative agent of soft tissue infections (postsurgical, posttraumatic, posttransplantation, postinjection, catheter infection, etc.), but only rarely as a ...
Lenka Ryskova +8 more
doaj +3 more sources
Disentangling the link between zebrafish diet, gut microbiome succession, and Mycobacterium chelonae infection. [PDF]
Anim Microbiome, 2023 Background Despite the long-established importance of zebrafish ( Danio rerio ) as a model organism and their increasing use in microbiome-targeted studies, relatively little is known about how husbandry practices involving diet impact the zebrafish gut ...
Sieler MJ +5 more
europepmc +4 more sources
Mycobacterium chelonae Cutaneous Infection: A Challenge for an Internist. [PDF]
Eur J Case Rep Intern Med, 2021 Cutaneous infections caused by the Mycobacterium chelonae complex show a heterogeneous clinical presentation, which varies according to the patient’s immune status. Most standard antimycobacterials have no effect against these species. Clarithromycin alone was shown to provide adequate treatment, although resistance has been reported. Consequently, the
Gaudêncio M +5 more
europepmc +6 more sources
Sudapyridine (WX-081) antibacterial activity against Mycobacterium avium, Mycobacterium abscessus, and Mycobacterium chelonae in vitro and in vivo [PDF]
mSphereSudapyridine (WX-081) is a structural analog of bedaquiline (BDQ), which shows anti-tuberculosis and non-tuberculous mycobacteria (NTM) activities but, unlike BDQ, did not prolong QT interval in animal model studies.
Luyao Zheng +8 more
doaj +3 more sources
Disseminated Mycobacterium Chelonae infection in an immunocompromised adult: An uncommon etiology of skin infection [PDF]
IDCasesMycobacterium Chelonae is a rapidly growing nontuberculous mycobacterium (NTM) that is ubiquitous in the environment and is associated with skin and soft tissue infections (1).
Biruk Amare +3 more
doaj +3 more sources
Disseminated Cutaneous Mycobacterium chelonae Infection in an Immunocompetent Patient. [PDF]
Cureus, 2023 We present a case report on disseminated cutaneous Mycobacterium chelonae infection with a sporotrichoid pattern in an immunocompetent patient. The aim of this report is to contribute to the existing knowledge on the clinical presentation and management ...
Martinez-Ortega JI +4 more
europepmc +2 more sources
A rare spontaneous breast abscess due to Mycobacterium chelonae: a case report. [PDF]
Surg Case Rep, 2023 Background Mycobacterium chelonae , a nontuberculous mycobacterium, commonly causes skin, soft tissue, eye, pulmonary, catheter-related, and post-surgical infections in patients with immunosuppression or trauma. M.
Sakatoku Y, Okada Y, Takahashi Y.
europepmc +2 more sources
Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection. [PDF]
Nat Commun, 2022 Mycobacterium chelonae is a rare cause of chronic disseminated cutaneous infections in immunocompromised patients. Multidrug-resistant M. chelonae infections present a challenge for treatment, and prolonged antimicrobial courses lead to significant ...
Little JS +9 more
europepmc +2 more sources
Emergence of Inducible Macrolide Resistance in Mycobacterium chelonae Due to Broad-Host-Range Plasmid and Chromosomal Variants of the Novel 23S rRNA Methylase Gene, erm(55). [PDF]
J Clin Microbiol, 2023 Macrolides are a mainstay of therapy for infections due to nontuberculous mycobacteria (NTM). Among rapidly growing mycobacteria (RGM), inducible macrolide resistance is associated with four chromosomal 23S rRNA methylase (erm) genes. ABSTRACT Macrolides
Brown-Elliott BA +15 more
europepmc +2 more sources