Results 101 to 110 of about 2,553 (217)

Immune Exhaustion in Chronic Infection and Cancer: Signaling Pathways and Therapeutic Interventions

MedComm, Volume 7, Issue 3, March 2026.
Immune exhaustion is a well‐established hallmark of both cancer and chronic infection. This review proposes a novel “infection–exhaustion–tumor axis” framework, wherein chronic pathogens (e.g., oncogenic viruses) evade immune surveillance by hijacking inflammatory signaling to drive immune cell exhaustion, thereby creating immunosuppressive niches ...
Yali Song, Yazhi Mo, Si Chen, Yuemei Chen, Chunying Zhang, Shanying Deng, Juan Liao, Yi He, Wei Wang, Weidong Zheng, Tingting Zeng   +10 more
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Polyphasic taxonomic analysis establishes Mycobacterium indicus pranii as a distinct species [PDF]

, 2009
Background: Mycobacterium indicus pranii (MIP), popularly known as Mw, is a cultivable, non-pathogenic organism, which, based on its growth and metabolic properties, is classified in Runyon Group IV along with M. fortuitum, M. smegmatis and M.
Vikram Saini, Saurabh Raghuvanshi, Gursaran P. Talwar, Niyaz Ahmed, Jitendra P. Khurana, Seyed E. Hasnain, Akhilesh K. Tyagi, Anil K. Tyagi, Ramy K. Aziz   +8 more
core   +2 more sources

Suppressive CD8+ T‐Cells Are Key Cellular Mediators of Extracorporeal Photopheresis

Journal of Clinical Apheresis, Volume 41, Issue 1, February 2026.
ABSTRACT Extracorporeal photopheresis (ECP) is a widely utilized immunomodulatory procedure with an incompletely defined mechanism. In graft‐versus‐host disease (GvHD) and transplant rejection, ECP is thought to induce immune tolerance by increasing regulatory CD4+ T‐cells, whereas in cutaneous T cell lymphoa it may enhance dendritic cell–mediated ...
Kai J. Rogers, Kathryn L. Eschbacher, Zeb Zacharias, Kshitija Kale, Michael P. Crawford, Charles Michael Knudson, Alexander W. Boyden, Nitin J. Karandikar   +7 more
wiley   +1 more source

Persistent immune thrombocytopenia heralds the diagnosis of Mycobacterium chimaera prosthetic valve endocarditis

IDCases, 2017
A 63 year old female was admitted for investigation of worsening renal insufficiency. During hospitalization she developed persistent immune thrombocytopenia refractory to supportive or immunosuppressive treatment.
Keith A. Sacco, M. Caroline Burton
doaj   +1 more source

Prosthetic valve endocarditis from Mycobacterium chimaera infection causing granulomatous interstitial nephritis

IDCases, 2020
Mycobacterium chimaera is a rare infection associated with cardiopulmonary bypass. We describe a case of granulomatous interstitial nephritis caused by M. chimaera in a patient with prosthetic aortic valve endocarditis.
Christopher Trautman, Jonathan R. Da Costa, Cherise Cortese, Nabeel Aslam   +3 more
doaj   +1 more source

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

MedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin, Minying Xiong, Aimin Jiang, Li Chen, Lihaoyun Huang, Kailai Li, Hank Z. H. Wong, Jian Zhang, Zaoqu Liu, Quan Cheng, Bufu Tang, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source

Feature of Adhesins Produced by Human Clinical Isolates of Mycobacterium intracellulare, Mycobacterium intracellulare subsp. chimaera and Closely Related Species [PDF]

, 2020
Louise Lefrançois, Thierry Cochard, Maxime Branger, Olivia Peuchant, Cyril Condé, Adeline Pastuszka, Camille Locht, Philippe Lanotte, Franck Biet   +8 more
openalex   +1 more source

Indagine sulla presenza di Map in allevamenti di bovine da latte nella provincia della Spezia [PDF]

, 2014
Mycobacterium avium paratuberculosis ( Map) è l'agente eziologico che causa una enterite granulomatosa progressiva cronica conosciuta come paratubercolosi o malattia di Johne, la quale colpisce principalmente i ruminanti domestici e selvatici.
ZANNARDI, ERIKA
core  

Hydrogels for Cancer Immunotherapy: Strategies From Construction to Application

MedComm, Volume 7, Issue 2, February 2026.
Hydrogels offer an innovative platform for cancer immunotherapy. Through tailorable crosslinking strategies, they form customizable drug delivery platforms that address diverse therapeutic requirements by loading specific immunotherapeutic agents. These systems demonstrate significant clinical potential for precise tumor immunotherapy.
Xiaohua Chen, Shan Wu, Yueyang Zhang, Lilu Feng, Yang Chen, Xuzhao Yang, Ke Men, Jiuqun Zhu, Ming Li   +8 more
wiley   +1 more source