Results 111 to 120 of about 77,563 (210)

Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi, Shotaro Aso, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga   +4 more
wiley   +1 more source

Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru, Nesrine Brahimi, Haleh Zabihi, Cathryn Sibbald, Kyle Seigel, Delaram Shojaei, Eric McMullen, Afsaneh Alavi, Lily Archaempong, Aaron M. Drucker, Adam Weizman, Kenneth Croitoru, Robert Inman, Vincent Piguet   +13 more
wiley   +1 more source

Pacemaker pocket infection due to Mycobacterium abscessus subspecies abscessus: A Case Report and Literature Review [PDF]

Medical Laboratory Journal
Background: Mycobacterium abscessus is a rapidly growing non-tuberculous mycobacterium that can cause various infections in humans. The identification of nontuberculous mycobacteria remains a challenge to date due to the availability of limited resources.
Maanasa Bhaskar Manalikandy, Ankita Mohanty, Noyal Maria Joseph, Raja Jaisundar Selvaraj, Sujatha Sistla   +4 more
doaj  

Non-tuberculous mycobacteria enhance the tryptophan-kynurenine pathway to induce immunosuppression and facilitate pulmonary colonization

Frontiers in Cellular and Infection Microbiology
The increasing prevalence of non-tuberculous mycobacterium (NTM) infections alongside tuberculosis (TB) underscores a pressing public health challenge. Yet, the mechanisms governing their infection within the lung remain poorly understood.
Longjie Li, Longjie Li, Jiaofang Shao, Chunran Tong, Weiwei Gao, Pan Pan, Chen Qi, Chenxi Gao, Yunlei Zhang, Yunlei Zhang, Ying Zhu, Cheng Chen   +11 more
doaj   +1 more source

Integrating tuberculosis and HIV services in low- and middle-income countries: a systematic review.

, 2012
OBJECTIVES: Given the imperative to scale up integrated tuberculosis (TB) and HIV services in settings where both are of major public health importance, we aimed to synthesise knowledge concerning implementation of TB/HIV service integration.
Atun, Briggs, Dixon-Woods, Dong, Gandhi, Gunneberg, Harris, Hausler, Laserson, Levin, Maher, Martinot, Micek, Miti, Moher, Ramachandran, Shakarishvilli, Shetty, Shrestha, Ssemafumu, Sutton, Terris-Prestholt, The World Bank Group, Thomas, USAID, Uyei, Van Rie, Vassall, Vijay, Wandwalo, WHO, WHO, WHO, WHO, WHO, WHO, Zachariah   +36 more
core   +1 more source

Granulomatous Panniculitis in a Patient Treated With Cemiplimab: Case Report and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) have become a cornerstone in the treatment of advanced malignancies by enhancing antitumor immunity, but they may also trigger a broad spectrum of immune‐related adverse events (irAEs) involving multiple organs.
B. Lada‐Colunga, J. L. Artola‐Igarza, N. Martinez‐Peña, I. Arevalo‐Ortega, J. Rodriguez‐Blandon, G. Cancho‐Galan, R. Izu‐Belloso   +6 more
wiley   +1 more source

Host Long Noncoding RNAs as Key Players in Mycobacteria–Host Interactions

Microorganisms
Mycobacterial infections, caused by various species within the Mycobacterium genus, remain one of the main challenges to global health across the world.
Stephen K. Kotey, Xuejuan Tan, Audrey L. Kinser, Lin Liu, Yong Cheng   +4 more
doaj   +1 more source

Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning

Macromolecular Rapid Communications, EarlyView.
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh, Cyrille Boyer, Priyank V. Kumar   +2 more
wiley   +1 more source

Evaluation of nucleotide MALDI-TOF-MS for the identification of Mycobacterium species

Frontiers in Cellular and Infection Microbiology
BackgroundThe accurate identification of the Mycobacterium tuberculosis complex (MTBC) and different nontuberculous mycobacteria (NTM) species is crucial for the timely diagnosis of NTM infections and for reducing poor prognoses.
Yelei Zhu, Zhengwei Liu, Lina Peng, Bin Liu, Kunyang Wu, Mingwu Zhang, Xiaomeng Wang, Junhang Pan   +7 more
doaj   +1 more source

Analysis of Research on the Effects of Improved Water, Sanitation, and Hygiene on the Health of People Living with HIV and AIDS and Programmatic Implications [PDF]

, 2007
This paper reviews the existing scientific and programmatic evidence, raises WASH issues in the HIV and AIDS context that need further study to build the evidence base, assesses current WASH guidance through a review of national HIV/AIDS guidelines from ...

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