Deciphering the Heterogeneity of Pulmonary Macrophages in Response to Fine Particles
Small, EarlyView.This study introduces a dual‐labeled gold nanoparticle model to capture particle–responsive cells via integrating fluorescence‐activated cell sorting and single‐cell RNA sequencing. Fourteen macrophage subsets are identified with response and function heterogeneity, among which AMs_3, AMs_7, and recMacs_4 subsets show stronger phagocytic activation ...
Qing'e Shan +11 more
wiley +1 more source
The addition of avibactam renders piperacillin an effective treatment for Mycobacterium abscessus infection in an in vivo model [PDF]
, 2018 Michal Meir, Pablo Bifani, Daniel Barkan
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World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu +7 more
wiley +1 more source
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
Acta Paediatrica, EarlyView.ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source
Mycobacterium novocastrense–associated Pulmonary and Wound Infections [PDF]
, 2011 Hasan Shojaei +3 more
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The return of metabolism: biochemistry and physiology of glycolysis
Biological Reviews, EarlyView.ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Vaccination inducing durable and robust antigen-specific Th1/Th17 immune responses contributes to prophylactic protection against Mycobacterium avium infection but is ineffective as an adjunct to antibiotic treatment in chronic disease [PDF]
, 2022 Ju Mi Lee +8 more
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Cutaneous non‐tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background Cutaneous non‐tuberculous mycobacterial infections (NTM) remain a diagnostic and therapeutic challenge. The aim of this study was to characterize cutaneous NTM infections in Germany over a 24‐year‐period. Patients and Methods 73 patients with cutaneous NTM infections diagnosed at 17 different German University Hospitals from 2000 ...
Luisa Bopp +6 more
wiley +1 more source
Infection for Mycobacterium tuberculosis and Nontuberculous Mycobacteria in the HIV/AIDS Patients
, 2011 Lilian María Mederos Cuervo
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