Results 241 to 250 of about 100,312 (295)

The Regulatory Mechanisms of Treponema pallidum Enolase on Macrophages: From Enzymatic Activity to Signal Transduction

The FASEB Journal, Volume 39, Issue 13, 15 July 2025.
ABSTRACT Syphilis, caused by the gram‐negative bacterium Treponema pallidum, remains a significant global public health threat. Despite the efficacy of antibiotic treatment in controlling syphilis, the pathogenic mechanisms of T. pallidum, particularly its interactions with the host immune system, are not well understood.
Peiyuan Sun, Suo Liu, Qilin Zeng, Weiwei Li, Sijia Li, Zhanpeng Wang, Yuanyuan Tang, Hongyu Yang, Dongde Xie, Jun Zhou, Yanxia Zhou, Kang Zheng, Yimou Wu   +12 more
wiley   +1 more source

Mycobacterium abscessus infection of uncertain etiology following lumbar spine decompression and instrumentation: illustrative case. [PDF]

J Neurosurg Case Lessons
Rhodes SV, Nawabi NLA, Saway BF, Triano MJ, Varma AK.   +4 more
europepmc   +1 more source

Glycans and Chirality: Stereoselectivity at the Core of DC‐SIGN's Recognition. A Novel View of the Optimum Minimal Ligand Epitope

Chemistry – A European Journal, Volume 31, Issue 37, July 2, 2025.
The stereochemical diversity of the “glycan code” enables similar chiral motifs to arise from both D‐ and L‐sugars. Focused on DC‐SIGN–glycan recognition, two diverse monosaccharide scaffolds, D‐Man (D‐Rha) and L‐Gal (L‐Fuc), maintain the exquisite stereochemistry encoded in the minimal binding epitope.
J. Daniel Martínez, Reyes Núñez‐Franco, Pablo Valverde, Sandra Delgado, Ana Ardá, Jesús Jiménez‐Barbero, Gonzalo Jiménez‐Oses, F. Javier Cañada   +7 more
wiley   +1 more source

A novel loss-of-function variant in <i>STAT1</i> causes Mendelian susceptibility to mycobacterial disease. [PDF]

Front Cell Infect Microbiol
Lv K, Gong Z, Fu Y, Zhao S, Song Y, Wang H, Lin Z.   +6 more
europepmc   +1 more source

A case report of peritoneal dialysis-associated peritonitis caused by <i>Mycobacterium mageritense</i>. [PDF]

IJID Reg
Ishikawa K, Kadota N, Nakayama M, Mori N.   +3 more
europepmc   +1 more source

Novel Quinazolinones Active against Multidrug‐Resistant Mycobacterium Tuberculosis: Synthesis, Antimicrobial Evaluation, and in Silico Exploration of Penicillin‐Binding Protein 1A as a Potential Target

ChemMedChem, Volume 20, Issue 13, July 1, 2025.
Quinazolinone‐based compounds emerge as potent antimycobacterial agents, showing low minimum inhibitory concentrations against drug‐resistant Mycobacterium tuberculosis. Molecular modeling uncovers a novel allosteric site in PonA1 targeted by these derivatives.
Marek Kerda, Daria Nawrot, Petr Šlechta, Miroslav Domanský, Asal Askari, Hanieh Kamangar, Ondřej Janďourek, Klára Konečná, Pavla Paterová, Ingrid Hlbočanová, Miloslav Macháček, Matteo Mori, Fiorella Meneghetti, Martin Doležal, Jan Zitko, Ghada Bouz   +15 more
wiley   +1 more source

Native Knee Septic Arthritis With <i>Mycobacterium Avium</i> Complex Treated With Primary Total Knee Arthroplasty With Antibiotic-Eluting Cement. [PDF]

Arthroplast Today
Schwartz AM, Deckey DG, Chun DS, Seyler TM, Watters TS.   +4 more
europepmc   +1 more source

Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of GATA2 Deficiency

Head &Neck, Volume 47, Issue 7, Page E82-E86, July 2025.
ABSTRACT Background GATA2 deficiency is a rare genetic disorder associated with hematologic, infectious, and neoplastic complications. We report a case of a patient with GATA2 deficiency who developed aggressive squamous cell carcinoma (SCC) of the head and neck, an atypical manifestation of this condition.
Brejjette Aljabi, James A. Stewart, Kirk Withrow, Carissa M. Thomas   +3 more
wiley   +1 more source