Results 61 to 70 of about 100,312 (295)

Mycobacterium mucogenicum Hand Infection in an Intravenous Drug Abuser

Case Reports in Infectious Diseases, 2018
Mycobacterium mucogenicum is a rapidly growing mycobacterium found ubiquitously in water sources. It has been reported to cause widespread infections with infection entry from wound or central venous catheters especially in immunocompromised patients ...
Sijan Basnet, Izza Mir, Rashmi Dhital, Garima Basnet, Nitin Patel   +4 more
doaj   +1 more source

Cutaneous infection with Mycobacterium obuense

International Journal of Mycobacteriology, 2018
This report describes the presence of cutaneous nodules and ulceration of the right leg of 1-year duration in an elderly woman. Prior biopsies had demonstrated dermal and subcutaneous granulomatous inflammation. Special stains for microorganisms and cultures were repeatedly negative. Polymerase chain reaction evaluation of the tissue block demonstrated
openaire   +4 more sources

Synthesis and Evaluation of Trehalose‐Based Mertansine Warheads for BCG Delivery of Anti‐Cancer Agents

ChemBioChem, Accepted Article.
Non‐muscle invasive bladder cancer (NMIBC) accounts for 75% of bladder cancer cases, with Bacillus Calmette‐Guérin (BCG) immunotherapy as the gold standard for high‐risk patients. BCG elicits a robust immune response but is limited by adverse effects and resistance. To enhance its efficacy, we developed a trehalose‐based conjugation strategy, tethering
Michael Grimmeisen, Xuan Wang, Melissa Weldle, Kerstin Sartory, Sara Benkhelifa, Yu Zhang, Trinh Dao, Jonas Meyer, Oliver Gorka, Olaf Groß, Claudia Jessen-Trefzer   +10 more
wiley   +1 more source

High Sensitivity L‐Cysteine Indium Telluriselenide Quantum Dot‐Inspired Aptasensor for Interferon Gamma TB Biomarker

ChemElectroChem, EarlyView.
An electrochemical interferon‐gamma (IFN‐γ) aptasensor is developed with L‐cysteine‐indium telluriselenide quantum dot (QD) and 24 mer guanine‐thymine DNA aptamer. The aptasensor exhibits high sensitivity in buffer and human serum samples. From calibration analysis, the limit of detection of the aptasensor is 0.312 pg mL−1 IFN‐γ, which indicates good ...
Kaylin Cleo Januarie, Usisipho Feleni, Candice Cupido, Nelia Abraham Sanga, Rachel Fanelwa Ajayi, Emmanuel Iheanyichukwu Iwuoha, Marlon Oranzie, Jaymi Leigh January, Zandile Dennis Leve   +8 more
wiley   +1 more source

Sporotrichoid-Like Spread of Cutaneous Mycobacterium chelonae in an Immunocompromised Patient

Case Reports in Dermatological Medicine, 2017
Mycobacterium chelonae is a rapidly growing mycobacterium found in water and soil that can cause local cutaneous infections in immunocompetent hosts but more frequently affects immunocompromised patients.
Daria Marley Kemp, Anusha G. Govind, Jun Kang, Caroline C. Brugger, Young C. Kauh   +4 more
doaj   +1 more source

Mycobacterium szulgai cavitary lung disease progression over a three year period – A case report

IDCases, 2022
Mycobacterium szulgai is a slow growing non-tuberculous mycobacterium associated with rare but severe infections. It most commonly presents as pulmonary disease in people with underlying structural lung disease.
Michael C. Croix, Sonal S. Munsiff
doaj  

Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723

Cytoskeleton, EarlyView.
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar, Joyeeta Chakraborty, Pananghat Gayathri, Ramanujam Srinivasan   +3 more
wiley   +1 more source

Mycobacterium riyadhense as the opportunistic infection that lead to HIV diagnosis: A report of 2 cases and literature review

Journal of Infection and Public Health, 2019
Human immunodeficiency virus (HIV) infection usually presents with a wide range of manifestations. Although HIV patients are prone to pulmonary infections by opportunistic pathogens in the late stage of AIDS, manifesting the disease with pulmonary ...
Thamer H. Alenazi, Bashayer S. Alanazi, Abdulrahman Alsaedy, Abdulmoneim Khair, Rifat Solomon, Sameera M. Al Johani   +5 more
doaj  

Synthesis, Antimycobacterial Activity, and Computational Insight of Novel 1,4‐Benzoxazin‐2‐one Derivatives as Promising Candidates against Multidrug‐Resistant Mycobacterium Tuberculosis

ChemMedChem, EarlyView.
A series of 14 novel 1,4‐benzoxazinone derivatives is tested against various strains of Mycobacterium tuberculosis. All compounds show high activity against all tested strains, particularly the resistant strains. Additionally, the novel derivatives exhibit low cytotoxicity toward mammalian Vero cells.
Maria Grazia Mamolo, Emanuele Carosati, Diletta Pasin, Alessandro De Logu, Gianluigi Cabiddu, Marko Jukič, Daniele Zampieri   +6 more
wiley   +1 more source

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium Tuberculosis: Progress Toward Novel Antitubercular Agents

ChemMedChem, EarlyView.
A series of 42 homoisoflavones were synthesized and evaluated against Mycobacterium tuberculosis (Mtb). Three derivatives showed potent inhibition of Mtb strains. Evaluation in infected macrophages revealed promising intracellular activity, where one derivative featuring a nitrofuranyl and piperidine group emerges as the most promising.
Sanderson D. Calixto, Juliane S. Falcão, Stella S. Antunes, Marlon H. Araujo, Alexandre L. B. Cunha, David R. Martins, Sarah M. R. Nascimento, Thatiana L. B. V. Simão, Elena B. Lasunskaia, Nelilma C. Romeiro, Paulo R. R. Costa, Michelle F. Muzitano, Guilherme S. Caleffi   +12 more
wiley   +1 more source