Results 41 to 50 of about 77,563 (210)
Skin and soft tissue infection by Mycobacterium intracellulare in an immunocompetent patient
IDCases, 2020 Nontuberculous mycobacteria (NTM) infections still represent a large group of insidious diseases hard to deal with. Traditionally, immunocompromised patients suffer from NTM infections, especially with respiratory involvement or disseminated diseases due
Alessio Pampaloni +9 more
doaj +1 more source
Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]
, 2013 Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown +27 more
core +2 more sources
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
Non-tuberculous mycobacterial soft tissue swelling in an immunocompetent patient
Medical Journal of Dr. D.Y. Patil University, 2014 Non-tuberculosis mycobacteria (NTM) include those mycobacterium species that are not members of the Mycobacterium tuberculosis complex. They assumed significance with the growing pandemic of the acquired immune deficiency syndrome (AIDS) since the 1980s,
Virendra S Athavale +3 more
doaj +1 more source
Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra. [PDF]
, 2019 The bacterium Mycobacterium tuberculosis (Mtb) causes tuberculosis and is responsible for more human mortality than any other single pathogen1. Progression to active disease occurs in only a fraction of infected individuals and is predicted by an ...
Chen, Katherine J +6 more
core
Human infections associated with wild birds. [PDF]
, 2008 IntroductionWild birds and especially migratory species can become long-distance vectors for a wide range of microorganisms. The objective of the current paper is to summarize available literature on pathogens causing human disease that have been ...
Bauchinger, Ulf +4 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Status and potential of bacterial genomics for public health practice : a scoping review [PDF]
, 2019 Background: Next-generation sequencing (NGS) is increasingly being translated into routine public health practice, affecting the surveillance and control of many pathogens.
Boon, Nele AM +6 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh +8 more
wiley +1 more source