Results 21 to 30 of about 77,563 (210)

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu   +11 more
wiley   +1 more source

In vitro activity of SPR719 against Mycobacterium ulcerans, Mycobacterium marinum and Mycobacterium chimaera.

open access: yesPLoS Neglected Tropical Diseases, 2021
Nontuberculosis mycobacterial (NTM) infections are increasing in prevalence across the world. In many cases, treatment options for these infections are limited.
Sacha J Pidot   +3 more
doaj   +1 more source

Molecular epidemiology of Mycobacterium bovis in Cameroon [PDF]

open access: yes, 2017
We describe the largest molecular epidemiological study of Bovine Tuberculosis (bTB) in a sub-Saharan African country with higher spatial resolution providing new insights into bTB. Four hundred and ninety-nine samples were collected for culture from 201
Asuquo, A.   +13 more
core   +2 more sources

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

open access: yesHepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández   +18 more
wiley   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

open access: yesHepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole   +12 more
wiley   +1 more source

Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]

open access: yes, 2016
Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core   +1 more source

Infections Caused by Nontuberculous Mycobacteria in Recipients of Hematopoietic Stem Cell Transplantation

open access: yesFrontiers in Oncology, 2014
Nontuberculous mycobacteria (NTM) are acid-fast bacteria that are ubiquitous in the environment and can colonize soil, dust particles, water sources and food supplies.
Khalid Ahmed Al-Anazi   +2 more
doaj   +1 more source

Mycobacterial infections in adult recipients of allogeneic hematopoietic stem cell transplantation: A cohort study in a high endemic area

open access: yesJournal of Microbiology, Immunology and Infection, 2020
Background: Mycobacterial infections are important and potentially life-threatening complications after organ transplantations. Notably, for the recipients of allogeneic hematopoietic stem cell transplantation (HSCT), there are a few supporting results ...
Yao-Chung Liu   +11 more
doaj   +1 more source

ClassTR: Classifying Within-Host Heterogeneity Based on Tandem Repeats with Application to Mycobacterium tuberculosis Infections. [PDF]

open access: yes, 2015
Genomic tools have revealed genetically diverse pathogens within some hosts. Within-host pathogen diversity, which we refer to as "complex infection", is increasingly recognized as a determinant of treatment outcome for infections like tuberculosis ...
Chindelevitch, L   +4 more
core   +3 more sources

Emerging and Re-Emerging Zoonoses of Dogs and Cats. [PDF]

open access: yes, 2014
Since the middle of the 20th century, pets are more frequently considered as "family members" within households. However, cats and dogs still can be a source of human infection by various zoonotic pathogens.
Chomel, Bruno B
core   +2 more sources

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