Reproductive tract infections: prevalence and risk factors in rural Bangladesh. [PDF]
OBJECTIVE: To determine the prevalence of and risk factors for reproductive tract infections among men and women in a rural community in Bangladesh. METHODS: In the Matlab area a systematic sample of married non-pregnant women aged 15-50 years was drawn ...
Hawkes, Sarah +8 more
core +4 more sources
The Effect of Mycobacterium avium Complex Infections on Routine Mycobacterium bovis Diagnostic Tests [PDF]
Bovine tuberculosis (bTB) is diagnosed in naturally infected populations exposed to a wide variety of other pathogens. This study describes the cell-mediated immune responses of cattle exposed to Mycobacterium avium subspecies paratuberculosis (Map) and ...
Bakker, D. +11 more
core +1 more source
Interferon-γ is a crucial activator of early host immune defense against Mycobacterium ulcerans infection in mice [PDF]
Buruli ulcer (BU), caused by infection with Mycobacterium ulcerans, is a chronic necrotizing human skin disease associated with the production of the cytotoxic macrolide exotoxin mycolactone.
Miriam Bolz +11 more
core +2 more sources
Mycobacterium tuberculosis Beijing genotype. [PDF]
Molecular epidemiologic studies of strains of Mycobacterium tuberculosis are currently conducted worldwide. The genetically distinct Beijing family of strains has been associated with large outbreaks of tuberculosis, increased virulence, and multidrug ...
Lillebaek, Troels +11 more
core +1 more source
Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination. [PDF]
Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis (TB), despite its variable protective efficacy. Relatively little is known about the immune response profiles following BCG vaccination in relation to protection against TB. Here we
Klein, Michèl R +12 more
core +1 more source
New drugs and vaccines for drug-resistant Mycobacterium tuberculosis infections [PDF]
Tuberculosis remains the most common cause of death due to a single infective organism. Despite the availability of a vaccine and chemotherapeutic options, the global disease burden remains relatively unaffected.
Willcox, Benjamin +12 more
core +1 more source
Worldwide occurrence of Beijing/W strains of Mycobacterium tuberculosis: a systematic review. [PDF]
Strains of the Beijing/W genotype family of Mycobacterium tuberculosis have caused large outbreaks of tuberculosis, sometimes involving multidrug resistance. This genetically highly conserved family of M.
Judith R. Glynn +10 more
core +1 more source
Mycobacterium tuberculosis acg Gene Is Required for Growth and Virulence In Vivo. [PDF]
Mycobacterium tuberculosis dosRS two-component regulatory system controls transcription of approximately 50 genes including hspX, acg and Rv2030c, in response to hypoxia and nitric oxide conditions and within macrophages and mice.
Hu, Y +6 more
core +2 more sources
Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans [PDF]
BACKGROUND: Mycolactones are a family of polyketide-derived macrolide exotoxins produced by Mycobacterium ulcerans, the causative agent of the chronic necrotizing skin disease Buruli ulcer.
Gerd Pluschke +27 more
core +2 more sources
Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu +11 more
wiley +1 more source

