Results 61 to 70 of about 1,040,351 (259)

Lady Windermere Syndrome: A Very Rare Entity In Indian Medical Scenario [PDF]

Journal of Clinical and Diagnostic Research, 2016
Bronchiectasis is a common respiratory disorder, which we come across in clinical practice. Patients with bronchiectasis are prone to infections, especially of Mycobacterium tuberculosis. However, non-tubercular Mycobacterial infections may also set in,
Raghavendra Rao, Shubha Sheshadri, Navin Patil, Karthik Rao, Avinash Arivazhahan   +4 more
doaj   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Co-infection by Streptococcus anginosus and Mycobacterium tuberculosis: three case reports

Journal of Medical Case Reports, 2009
Introduction Bacterial infections may appear as sequelae of remote tuberculous infections, especially thoracic infections. The simultaneous appearance of tuberculosis and bacterial infection is not common, and, to our knowledge, the association of ...
Rabuñal Ramón, Corredoira Juan, Monte Rafael, Coira Amparo   +3 more
doaj   +1 more source

Two Years of Ocrelizumab Treatment in Black and Hispanic People with Multiple Sclerosis in CHIMES: A Single‐Arm Clinical Trial

Annals of Neurology, EarlyView.
Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Lilyana Amezcua, Anthony T. Reder, Evanthia Bernitsas, Nancy L. Monson, Timothy Vartanian, Gregory F. Wu, Mansoor Saleh, Annette Okai, Ahmed Z. Obeidat, Dilraj Sokhi, Rikisha Parekh, Jinglan Pei, Christopher Harp, David Clayton, Ibraheem Abioye, Mitzi J. Williams, for the CHIMES Study Group   +16 more
wiley   +1 more source

Within-Host Dynamics of Multi-Species Infections:Facilitation, Competition and Virulence [PDF]

, 2012
Host individuals are often infected with more than one parasite species (parasites defined broadly, to include viruses and bacteria). Yet, research in infection biology is dominated by studies on single-parasite infections.
Eswarappa, Sandeepa M., Sylvie Estrela, Sam P Brown, Sylvie Estrela (156401), Estrela, Sylvie, Sam P. Brown (30600), Brown, Sam P., Sandeepa M Eswarappa, Sandeepa M. Eswarappa (156396)   +8 more
core   +2 more sources

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Osteomyelitis Infection of Mycobacterium marinum: A Case Report and Literature Review

Case Reports in Infectious Diseases, 2015
Mycobacterium marinum (M. marinum) is a ubiquitous waterborne organism that grows optimally at temperatures around 30°C. It is a nontuberculous Mycobacterium found in nonchlorinated water with worldwide prevalence.
Hao H. Nguyen, Nada Fadul, Muhammad S. Ashraf, Dawd S. Siraj   +3 more
doaj   +1 more source

Bone and joint infections due to opportunistic mycobacteria, a review of French experience

International Journal of Mycobacteriology, 2015
Aims and objectives: Bone and joint infections due to environmental mycobacteria are rare and can develop very slowly. The source for these outbreaks is generally tap water supplies.
Véronique Vincent
doaj   +1 more source

Mixed Mycobacterium kansasii and Mycobacterium smegmatis infection in an adult‐onset immunodeficiency patient with anti‐interferon‐γ autoantibodies

Respirology Case Reports, 2023
Anti‐interferon‐gamma autoantibody (AIGA) is a rare adult‐onset immunodeficiency disease that increases the risk of occult infection. Nontuberculous mycobacteria (NTM) infections represent a diverse group of species and subspecies, and mixed infections ...
Yun‐Tse Chou, Wei‐An Liao, Chin‐Wei Kuo   +2 more
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source