Results 61 to 70 of about 30,636 (254)

A case of hepatitis B and mycobacterium leprae co-infection causing challenges in diagnosis and treatment [PDF]

, 2021
Abate Bane
openalex   +1 more source

Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu, Maryam Ebunoluwa Zakariya, Abdulmuheez Abiola Abdulkareem, Olalekan Toheeb Okewale, Muhammad Halima Idris, Halimah Oluwayemisi Olayiwola   +5 more
wiley   +1 more source

M. leprae inhibits apoptosis in THP-1 cells by downregulation of Bad and Bak and upregulation of Mcl-1 gene expression

BMC Microbiology, 2006
Background Virulent Mycobacterium leprae interfere with host defense mechanisms such as cytokine activation and apoptosis. The mitochondrial pathway of apoptosis is regulated by the Bcl-2 family of proteins.
Tayyebi Ali, Ashraf Mussarat, Hasan Zahra, Hussain Rabia   +3 more
doaj   +1 more source

Skeletal Evidence for Leprosy in India by the Second Millenium B.C. [PDF]

, 2009
Leprosy is a chronic infectious disease caused by _Mycobacterium leprae_ that affects almost 500,000 people worldwide^1^. The timing of first infection, geographic origin, and pattern of transmission of the disease are unknown^1-3^.
Gwendolyn Robbins, Kelsey Gray, Malcolm Schug, RK Mohanty, Veena Tripathy, VN Misra, VS Shinde   +6 more
core   +1 more source

Schistosoma haematobium infection and Buruli ulcer [PDF]

, 2004
No abstract ...
Aguiar, Julia, Debacker, Martine, Gryseels, Bruno, Guedenon, Augustin, Johnson, Roch C., Kestens, Luc, Portaels, François, Scott, Janet T.   +7 more
core   +3 more sources

The role of red squirrels in leprosy dynamics in the United Kingdom: a critical review

One Health
In the United Kingdom, the declining population of the red squirrel, the acknowledged historical reservoir for zoonotic Mycobacterium leprae leprosy, is thought to have been behind the decline in leprosy.
S. Souguel, T. Oueslati, G. Grine, M. Drancourt   +3 more
doaj   +1 more source

MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]

, 2012
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
A Freitag, A Gevorgyan, A Mithani, Albert Gevorgyan, AM Feist, AM Feist, AM Feist, Andrzej M. Kierzek, AP Burgard, BA Pfeifer, CS Henry, D Nagrath, DC Alexander, DC Stevens, EM Paradise, Eriko Takano, FC Lee, H Ikeda, I Thiele, J Gonzalez-Lergier, J Romero, J Schellenberger, JD Orth, JL Adrio, JP Brooks, JS Edwards, K Nieselt, K Yanai, LM Blank, M DeJongh, M Durot, M Kanehisa, M Latendresse, MA Fischbach, MA Oberhardt, MA Oberhardt, MA Oberhardt, Marnix H. Medema, MH Medema, MH Medema, MH Medema, MH Medema, MT Alam, MT Alam, MW Covert, N Scherr, ND Price, ND Price, NE Lewis, Piotr Zakrzewski, PR Ives, R Breitling, R Schuetz, Rainer Breitling, SA Becker, SD Bentley, Stephen S. Fong, TD Vo, TY Kim, XQ Zhao   +59 more
core   +6 more sources

Persistent Facial Nodules in an Elderly Patient

JEADV Clinical Practice, EarlyView.
Qian Ding, Qin‐Si Liu, Heng‐Guang Zhao   +2 more
wiley   +1 more source

Uncovering Insights Into the Biology of Mycobacterium tuberculosis Using Genetic Tools

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Genetic manipulation tools such as homologous recombination, CRISPR‐Cas systems, and gene knock‐out/knock‐down strategies have advanced Mycobacterium tuberculosis (Mtb) research, despite challenges posed by its slow growth, complex pathology, and drug resistance.
Alessandro Stamilla, Deborah Recchia, Giovanni Stelitano, Ludovica Maci, Maria Concetta Marturano, Edda De Rossi, Laurent Roberto Chiarelli, Maria Rosalia Pasca, Giulia Degiacomi   +8 more
wiley   +1 more source

Variation of TTC Repeat Pattern in the Dna of Mycobacterium Leprae Isolates Obtained From Archeological Bones and Leprosy Patients From East Nusa Tenggara [PDF]

, 2012
The existence of leprosy or kusta or Morbus Hansen or Hansens disease has been known for years, including in Indonesia. Starting from the discovery of Mycobacterium leprae isolates from ancient bone (about 1.000 years B.C), the archaeological excavations
Adriaty, D. (Dinar), Agusni, I. (Indropo), Aksono, B. (Bimo), Iswahyudi, I. (Iswahyudi), Izumi, S. (Shinzo), Koesbardiati, T. (Toetik), Wahyuni, R. (Ratna)   +6 more
core   +1 more source