Results 71 to 80 of about 14,313 (203)

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Recent advances in nontuberculous mycobacterial lung infections [version 1; peer review: 2 approved]

F1000Research, 2019
Nontuberculous mycobacteria (NTM) are members of the Mycobacterium genus other than Mycobacterium tuberculosis complex and Mycobacterium leprae. NTM are widely distributed in the environment and are increasingly recognized as causes of chronic lung ...
David Horne, Shawn Skerrett
doaj   +1 more source

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

FEBS Letters, Volume 599, Issue 7, Page 971-988, April 2025.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin, Danielle M. Colussi, Peter B. Stathopulos   +2 more
wiley   +1 more source

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

Advanced Therapeutics, Volume 8, Issue 4, April 2025.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap, Pankaj R. Khuspe, Sagar R. Pardeshi, Md Jasim Uddin, Ushasi Das, Navnath T. Hatvate, Satish Rojekar, Prabhanjan Giram, Mohammad Khalid, Yahya E. Choonara, Md. Faiyazuddin   +10 more
wiley   +1 more source

Lepra: revisión bibliográfica a propósito de un caso clínico

Ateneo, 2021
La lepra es una enfermedad infecciosa que afecta a la piel, mucosas del tracto respiratorio superior, ojos y nervios periféricos, los microorganismos responsables son Mycobacterium leprae y Mycobacterium lepromatosis.
Pedro Martínez Borrero, Mauricio Coello, Pablo Ortega, Mauricio Merchán, Paola Belen Delgado Palacios   +4 more
doaj  

Intracellular Mycobacterium leprae Utilizes Host Glucose as a Carbon Source in Schwann Cells

mBio, 2019
New approaches are needed to control leprosy, but understanding of the biology of the causative agent Mycobacterium leprae remains rudimentary, principally because the pathogen cannot be grown in axenic culture.
Khushboo Borah, Karina do Carmo de Vasconcelos Girardi, Tom A. Mendum, Leticia Miranda Santos Lery, Dany J. V. Beste, Flavio Alves Lara, Maria Cristina Vidal Pessolani, Johnjoe McFadden   +7 more
doaj   +1 more source

Pulmonary Nontuberculous Mycobacteria Infection in Bronchiectasis: A Narrative Review of Current Status and Future

Health Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims Pulmonary nontuberculous mycobacteria (NTM) infection and bronchiectasis are two distinct respiratory conditions, but bronchiectasis and pulmonary NTM infections are closely associated. NTM can cause bronchiectasis.
Masaki Fujita
wiley   +1 more source

Aspectos epidemiológicos da hanseníase na cidade de Recife, PE em 2002 Epidemiologic aspects of leprosy in the city of Recife, Pernambuco state, 2002

Anais Brasileiros de Dermatologia, 2004
FUNDAMENTOS: Ainda é de grande importância a hanseníase como problema de Saúde Pública no Brasil, devido a sua alta endemicidade. OBJETIVO: Determinar as principais características dessa enfermidade na cidade de Recife no ano de 2002.
Sylvia Lemos Hinrichsen, Millena Raphaella Silva Pinheiro, Moacir Batista Jucá, Hévila Rolim, Guilherme José da Nóbrega Danda, Diana Maria R. Danda   +5 more
doaj   +1 more source

Hanseníase simulando erupção liquenóide: relato de caso e revisão de literatura Leprosy simulating lichenoid eruption: case report and literature review

Anais Brasileiros de Dermatologia, 2010
A hanseníase relaciona-se à formação de grande variedade de lesões cutâneas, desde manchas, pápulas, placas e nódulos, até infiltração difusa, dependendo da resposta imune do indivíduo.
Antônio Renê Diógenes de Sousa, Carolina Oliveira Costa, Hercilia Maria Carvalho Queiroz, Paulo Eduardo de Sá Gonçalves, Heitor de Sá Gonçalves   +4 more
doaj   +1 more source

Dapsone resistance inMycobacterium leprae

Leprosy Review, 2000
The folP1 gene of Mycobacterium leprae, which encodes dihydropteroate synthase (DHPS), was studied for the presence of mutations associated with resistance to dapsone (DDS). When the folP1 of several DDS-resistant clinical isolates of M. leprae were sequenced, two missense mutations were identified.
D L Williams, Thomas P. Gillis
openaire   +3 more sources