Results 71 to 80 of about 187,712 (288)
BCG and adverse events in the context of leprosy [PDF]
Background: Notwithstanding its beneficial immunoprophylactic outcomes regarding leprosy and childhood TB, BCG vaccination may cause adverse events, particularly of the skin.
Annemieke Geluk +7 more
core +3 more sources
A major T cell antigen of Mycobacterium leprae is a 10-kD heat-shock cognate protein. [PDF]
Several mycobacterial antigens, identified by monoclonal antibodies and patient sera, have been found to be homologous to stress or heat-shock proteins (hsp) defined in Escherichia coli and yeast.
Alland, D +9 more
core
Although Mycobacterium leprae was one of the first bacterial pathogens of humans to be described (Hansen, 1874), progress on understanding the basic biology and pathogenicity of this organism has been greatly hampered by the inability to find a conventional laboratory medium or tissue culture system that can support its growth.
openaire +1 more source
Cultivation of Mycobacterium Leprae
McKinley and Soule1 reported the successful cultivation of Mycobacterium leprae, obtained from Puerto Rican lepers, on several culture media. Subsequent reports were made by Soule and McKinley2, 3 when their nonchromogenic strain of acid-fast bacilli, believed to be the true Mycobacterium leprae, had been carried through the eighth and sixteenth ...
Elizabeth Verder, Earl B. McKinley
openaire +2 more sources
Pixelated pathologies: Camera trapping as a tool for monitoring wildlife health
Given the increasing emergence of diseases, some with conservation and public health implications, improving and expanding wildlife health surveillance strategies is imperative. Camera trapping is particularly relevant for detecting new outbreaks, monitoring high‐risk zones and evaluating risk mitigation measures. Abstract Camera trapping has become an
Patricia Barroso, Pablo Palencia
wiley +1 more source
Lipid Body–Phagosome Interaction in Macrophages during Infectious Diseases: Host Defense or Pathogen Survival Strategy? [PDF]
Phagocytosis of invading microorganisms by specialized cells such as macrophages and neutrophils is a key component of the innate immune response. These cells capture and engulf pathogens and subsequently destroy them in intracellular vacuoles—the ...
Dvorak, Ann Marie, Melo, Rossana C. N.
core +2 more sources
Subversion of Schwann Cell Glucose Metabolism by Mycobacterium leprae*
Mycobacterium leprae, the intracellular etiological agent of leprosy, infects Schwann promoting irreversible physical disabilities and deformities. These cells are responsible for myelination and maintenance of axonal energy metabolism through export of ...
R. C. Medeiros +19 more
semanticscholar +1 more source
Considering that the main route of Mycobacterium leprae transmission is the upper respiratory tract, detection of salivary antibodies can be a useful tool for diagnosing early infection.
Alexandre Casimiro de Macedo +4 more
doaj +1 more source
Diagnostic assays for leprosy based on T-cell epitopes. [PDF]
To date, only a limited number of antigens have been described as specific for Mycobacterium leprae, and in many cases, homologues have subsequently been shown to exist in mycobacteria such as M. avium and M. intracellulare.
Brahmbhatt, S +16 more
core +1 more source
Viability of Mycobacterium leprae in the environment and its role in leprosy dissemination
Background: Leprosy, a chronic disease caused by Mycobacterium leprae, is a public health concern in certain countries, including India. Although the prevalence of the disease has fallen drastically over time, new cases continue to occur at nearly the ...
P. Mohanty +10 more
semanticscholar +1 more source

