Results 221 to 230 of about 380,966 (308)

A co-evolutionary perspective on humans and <i>Mycobacterium tuberculosis</i> in the era of systems biology. [PDF]

Elife
Reichmann MT, Tezera LB, Denney L, Schiff H, Vallejo A, Mansour S, Leslie A, Garay-Baquero DJ, Elkington PT.   +8 more
europepmc   +1 more source

Virulence of Mycobacterium tuberculosis after Acquisition of Isoniazid Resistance: Individual Nature of katG Mutants and the Possible Role of AhpC

, 2016
Luisa María Nieto Ramírez, Carolina Mehaffy, Elizabeth Creissen, JoLynn Troudt, Amber Troy, Helle Bielefeldt‐Ohmann, Marcos Burgos, Angelo Izzo, Karen M. Dobos   +8 more
openalex   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source

Inhibition of de novo fatty acid synthesis in Mycobacterium tuberculosis. [PDF]

J Biol Chem
Roszkowski EK, Charap S, Montague CR, Sukheja P, McNamara CW, Soma PS, Islam MN, Graham B, Grzegorzewicz AE, Jackson M, Yang B, Hay AG, Russell DG, Belisle JT, VanderVen BC.   +14 more
europepmc   +1 more source

Activity of Riminophenazines against Mycobacterium tuberculosis: A Review of Studies that Might be Contenders for Use as Antituberculosis Agents

, 2020
Mpelegeng Victoria Bvumbi
openalex   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

Genomic epidemiology of Mycobacterium tuberculosis in Wales. [PDF]

Sci Rep
Pacchiarini N, Simkin F, Postans M, Ahern G, Song J, Brown C, Smith J, Williams C, Backx M, Thomas D, Connor TR, Williams C.   +11 more
europepmc   +1 more source

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection

Advanced Science, Volume 13, Issue 2, 9 January 2026.
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi, Bihan Xu, Dan Cao, Kaijin Xu, Ying Zhang   +4 more
wiley   +1 more source

Virulence hierarchies within the <i>Mycobacterium tuberculosis</i> complex. [PDF]

Proc Natl Acad Sci U S A
Danchuk SN, Duffy SC, Sullivan J, Beenish Rufai S, McIntosh FA, Lupien A, Harrison LB, Ghasemi Goojani H, Taylor L, Wei Y, Joubert P, Mortensen R, Chen JM, Niroula N, Stevens R, Norleen C, Kapur V, Behr MA.   +17 more
europepmc   +1 more source