Results 271 to 280 of about 380,966 (308)

Robust Diagnostic and Therapeutic Biomarkers for Tuberculosis Identified Through Multi‐Omics and Mendelian Randomization Analysis

MedComm, Volume 7, Issue 1, January 2026.
We performed UPLC‐MS/MS lipidomics and DIA proteomics on plasma from healthy controls, active TB patients, and cured patients, and used Mendelian randomization to prioritize diagnostic and cure biomarkers. Multi‐omics random‐forest models based on these biomarkers showed excellent performance for diagnosis and cure monitoring.
Chenglin Zhu, Jiaxi Chen, Ying Li, Qi Zhang, Qiqi Lu, Ningxuan Zhang, Hao Fan, Muhammad Mahtab Aslam Khan Khakwani, Lei Zhang, Ji‐Cheng Li   +9 more
wiley   +1 more source

Transcript-Capture sequencing enriches mRNA of <i>Mycobacterium tuberculosis</i> from host samples. [PDF]

NAR Mol Med
Lamont EI, Jones RM, Assadi J, Morrison R, Song T, Yu X, Weiner DM, Via LE, Winter J, Ma S, Wilkinson RJ, Barry CE, Sherman DR.   +12 more
europepmc   +1 more source

CCR2 Orchestrates Preferential Homing and Therapeutic Efficacy of Gingival Mesenchymal Stem Cell‐Derived Extracellular Vesicles in Rheumatoid Arthritis

MedComm, Volume 7, Issue 1, January 2026.
CCR2 orchestrates preferential homing of GMSC‐derived extracellularvesicles to inflamed joints in rheumatoid arthritis. ABSTRACT The clinical utility of mesenchymal stem cells (MSCs) is often limited by pulmonary entrapment and poor systemic distribution, particularly in diseases constrained by physiological barriers such as rheumatoid arthritis (RA ...
Jingrong Chen, Xiao Guan, Wenbin Wu, Luyao Wu, Yan Liu, Donglan Zeng, Junlong Dang, Jun Zhao, Julie Wang, Jia Yuan, Xiaoli Fan, Yunfeng Pan, Nancy Olsen, Song Guo Zheng   +13 more
wiley   +1 more source

Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry

ChemistryOpen, Volume 15, Issue 1, January 2026.
Piperazine‐based bioactive molecules represent a versatile class of compounds with broad therapeutic potential. Structural modification of the piperazine scaffold governs key structure–activity relationships, enabling antibacterial, antifungal, antitumor, neuroactive, and anti‐inflammatory activities.
Assel Ten, Raushan Koizhaiganova, Dilnaz Bissenbay, Bagila Tursynova, Zhanar Zhaxibayeva, Valentina Yu   +5 more
wiley   +1 more source

<i>MCP-1/CCR2</i> axis regulates M2 macrophage polarization and immunosuppression in mycobacterium tuberculosis. [PDF]

Front Immunol
Zhao G, Guo C, Li X, Tan L, Chen X, Tian F, Zhang L, Wang X, Cui J.   +8 more
europepmc   +1 more source

Group B streptococcal sacroiliitis following an uncomplicated vaginal delivery: A case report and review of the literature

Pregnancy, Volume 2, Issue 1, January 2026.
Abstract Background Pregnant and postpartum patients are at risk of infectious sacroiliitis due to the increased demand on the sacroiliac joint as well as the changes in the pelvis during pregnancy and delivery. Case We present the case of a 34‐year‐old woman who developed severe back pain following an uncomplicated vaginal delivery and was ultimately ...
Christina N. Schmidt, Marika Osterbur Badhey, Jeremiah Alexander, Sarah C. Lassey   +3 more
wiley   +1 more source

In host mutational adaptation of Mycobacterium tuberculosis complex strains

Zhang H, Medina-Jaudes N, Forcada-Nadal A, Harrison EM, Coll F.   +4 more
europepmc   +1 more source

Detection of rifampin-resistant Mycobacterium tuberculosis using CRISPR/Cas14a-enabled molecular techniques. [PDF]

BMC Infect Dis
Wu G, Ren Y, Wang Y, Zhao Y, Wu Y, Sun H, Sun Z, Wang R, Du Z.   +8 more
europepmc   +1 more source

Tre-DST: A Drug Susceptibility Test for <i>Mycobacterium tuberculosis</i> Using Solvatochromic Trehalose Probes. [PDF]

ACS Infect Dis
Schwartz LA, Brodeth AL, Susilo CT, Rodolf AA, Ivanov T, Mendoza Corrales E, Kumar SS, Kamariza M.   +7 more
europepmc   +1 more source

Estimation of second line anti-tubercular drug susceptibility to <i>Mycobacterium tuberculosis</i> in clinical isolates. [PDF]

Iran J Microbiol
Sudersanan H, Ravikumar NM, Mishra B.
europepmc   +1 more source