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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1997
Mycophenolate mofetil is the morpholinoethylester prodrug of mycophenolic acid, an agent that inhibits the proliferation of B and T lymphocytes through noncompetitive, reversible inhibition of inosine monophosphate dehydrogenase, a key enzyme in the de novo synthetic pathway of guanine nucleotides.
T M, Sievers +6 more
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Mycophenolate mofetil is the morpholinoethylester prodrug of mycophenolic acid, an agent that inhibits the proliferation of B and T lymphocytes through noncompetitive, reversible inhibition of inosine monophosphate dehydrogenase, a key enzyme in the de novo synthetic pathway of guanine nucleotides.
T M, Sievers +6 more
openaire +2 more sources
Dermatologic Therapy, 2007
Mycophenolate mofetil (MMF) is a relatively new systemic immunosuppressive agent whose use is rapidly increasing within the field of dermatologic. Originally used in the 1970s for the treatment of psoriasis, MMF has demonstrated efficacy in multiple types of inflammatory skin diseases.
Jeffrey, Zwerner, David, Fiorentino
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Mycophenolate mofetil (MMF) is a relatively new systemic immunosuppressive agent whose use is rapidly increasing within the field of dermatologic. Originally used in the 1970s for the treatment of psoriasis, MMF has demonstrated efficacy in multiple types of inflammatory skin diseases.
Jeffrey, Zwerner, David, Fiorentino
openaire +2 more sources
The Lancet, 1996
Mycophenolate mofetil (MMF), the morpholinoethyl ester of mycophenolic acid (MPA), is a new selective immunosuppressant used for the prevention and treatment of acute renal rejection after transplantation. In vivo MMF is deesterified to MPA, which is a potent and specific inhibitor of de novo purine synthesis and suppressor of both T and B lymphocyte ...
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Mycophenolate mofetil (MMF), the morpholinoethyl ester of mycophenolic acid (MPA), is a new selective immunosuppressant used for the prevention and treatment of acute renal rejection after transplantation. In vivo MMF is deesterified to MPA, which is a potent and specific inhibitor of de novo purine synthesis and suppressor of both T and B lymphocyte ...
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Transplantation Proceedings, 1999
MMF has taken its place in our immunosuppressive armamentarium. It has proven efficacy in preventing AR in a variety of types of transplantation.
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MMF has taken its place in our immunosuppressive armamentarium. It has proven efficacy in preventing AR in a variety of types of transplantation.
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Mycophenolate mofetil (Cellcept)
Expert Opinion on Investigational Drugs, 1998Mycophenolate mofetil (MMF) is a new immunosuppressive drug designed to inhibit inosine monophosphate dehydrogenase (IMPDH). IMPDH is a key enzyme in the purine synthesis pathway of lymphocytes. IMPDH is crucially important for the proliferative responses of human T- and B-lymphocytes.
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Revue medicale de Bruxelles, 1998
Mycophenolate Mofetil (MMF) is a new immunosuppressive agent that selectively inhibits the proliferation of T and B lymphocytes. The use of MMF in renal transplantation significantly reduced the incidence of acute rejection episodes in the first year after transplantation. The main toxicities of MMF are the occurrence of diarrhea and leucopenia.
Abramowicz, Daniel +3 more
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Mycophenolate Mofetil (MMF) is a new immunosuppressive agent that selectively inhibits the proliferation of T and B lymphocytes. The use of MMF in renal transplantation significantly reduced the incidence of acute rejection episodes in the first year after transplantation. The main toxicities of MMF are the occurrence of diarrhea and leucopenia.
Abramowicz, Daniel +3 more
openaire +2 more sources