Results 101 to 110 of about 48,159 (229)

Infection risk in patients with autoimmune cytopenias and immune dysregulation treated with mycophenolate mofetil and sirolimus

Frontiers in Immunology
IntroductionAutoimmune cytopenias (AICs) are a group of disorders characterized by immune-mediated destruction of blood cells. In children, they are often secondary to immune dysregulation that may require long-lasting immunosuppression.
Mattia Comella, Mattia Comella, Elena Palmisani, Marcello Mariani, Gianluca Dell’Orso, Maria Licciardello, Maria Carla Giarratana, Luca Arcuri, Sara Pestarino, Alice Grossi, Marina Lanciotti, Giorgia Brucci, Daniela Guardo, Giovanna Russo, Carlo Dufour, Francesca Fioredda, Elio Castagnola, Maurizio Miano   +17 more
doaj   +1 more source

Cutaneous Squamous Cell Carcinoma Amongst Solid Organ Transplant Recipients: A Systematic Review of Molecular Alterations

JEADV Clinical Practice, EarlyView.
ABSTRACT Background As solid organ transplantation becomes more prevalent, more patients are living on long‐term immunosuppression, greatly increasing the risk of cutaneous squamous cell carcinoma (cSCC). Although significant improvements have been achieved in the treatment of cSCC, further studies are needed to identify the specific protein expression
William Murray, Robin Caird, Michael O'Connor, Ciara Drumm, Emma O'Hora, Franklin Crossen, Aoife Lally, Aurelie Fabre, Roisin Dolan   +8 more
wiley   +1 more source

Systemic Immunosuppression to Reduce Surgical Intervention in ANCA‐Negative Subglottic Stenosis

The Laryngoscope, EarlyView.
Idiopathic subglottic stenosis (iSGS) typically follows an indolent course managed with surgical dilatation, though a subset demonstrates aggressive, recurrent disease. In this retrospective cohort study, systemic immunosuppression significantly prolonged inter‐dilation intervals in both granulomatosis with polyangiitis‐associated SGS and an “atypical”
Guy Benshetrit, Stephen McAdoo, Romana Kuchai, Charles Pusey, Guri Sandhu, Chadwan Al‐Yaghchi   +5 more
wiley   +1 more source

Mycophenolate mofetil: safety and efficacy in the prophylaxis of acute kidney transplantation rejection

Therapeutics and Clinical Risk Management, 2009
Pranav Dalal1, Monica Grafals2, Darshika Chhabra2, Lorenzo Gallon21Department of Medicine, Mount Sinai Hospital, Chicago, USA; 2Northwestern University–Feinberg School of Medicine, Chicago, USAAbstract: Mycophenolate mofetil (MMF), a prodrug of
Pranav Dalal, Monica Grafals, Darshika Chhabra, Lorenzo Gallon   +3 more
doaj  

Practical Approach to Managing SCIg Treatment in Patients With Chronic Inflammatory Demyelinating Polyneuropathy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Guidelines for the management of chronic inflammatory demyelinating polyneuropathy (CIDP) recommend corticosteroids, intravenous immunoglobulin (IVIg), or plasma exchange for first‐line therapies and subcutaneous immunoglobulin (SCIg) as a maintenance option.
Tuan Vu, Claudia Guerra, Niraja Suresh, Sami Khella, Jamie Morrell, Michael Pulley, Nan Jiang, Khema Sharma, Tulio Bertorini, Nivedita Jerath, Amanda Peltier   +10 more
wiley   +1 more source

A Rapidly Progressive Necrotic Ulcer in an Immunocompromised Patient

JEADV Clinical Practice, EarlyView.
R. Almutairi, H. Alajmi, M. Nouh, F. Alenezi, H. Al‐Sabah, A. Allafi   +5 more
wiley   +1 more source

Experience Using Efgartigimod to Treat Juvenile Myasthenia Gravis in China: A Multicenter Retrospective Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Current therapeutic management of juvenile myasthenia gravis (JMG) predominantly relies on conventional immunosuppressive therapies and expert consensus extrapolated from adult data, creating a critical gap in high‐quality, pediatric‐specific clinical evidence.
Jing Lin, Guoyan Qi, Susan Luo, Qilong Jiang, Bitao Bu, Min Liu, Yuzhen Wei, Meigui Han, Junhong Yang, Zhilan Zhao, Lili Zhang, Yifan Zhang, Haoyou Xu, Xingjie Hao, Zhijun Li   +14 more
wiley   +1 more source

Increased Prevalence of Extrathymic Neoplasms in Myasthenia Gravis Patients‐A Population‐Based, Matched Case–Control Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Myasthenia gravis (MG) is associated with thymic neoplasms. However, an increased prevalence of extrathymic neoplasms has also been reported. This study aimed to evaluate the rates of malignancy in MG patients while accounting for risk factors such as disease characteristics and immunomodulatory treatments.
Keshet Pardo, Tasneem Kab, Mark A. Hellmann, Itay Lotan, Tzippy Shochat, Nadav Loebl, Bar Yacobi, Yitzhak Friedman, Leor Perl, Nitai Shimon, Yiska Loewenberg Weisband, Liya Bieber, Eitan Auriel, Adi Wilf‐Yarkoni   +13 more
wiley   +1 more source

A Review of NIDDK‐Funded Studies of Urological Chronic Pain Conditions

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction This review highlights NIDDK‐funded clinical research studies focused on interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods Since 1987, the NIDDK has funded numerous cohort studies, epidemiologic studies, and clinical trials for these conditions.
J. Quentin Clemens
wiley   +1 more source

Liver Transplantation After Combination Therapy Based on Immune Checkpoint Inhibitors: A Multicenter Retrospective Study of Safety and Efficacy

Organ Medicine, EarlyView.
This multicenter retrospective study assessed preoperative immune checkpoint inhibitor (ICI) therapy in 17 hepatocellular carcinoma patients undergoing liver transplantation. All received at least one cycle of ICI‐based combination therapy before transplant and achieved a 76.5% objective response rate.
Huanquan Chen, Tianxing Dai, Jie Gao, Chuanjiang Li, Huanwei Chen, Feiwen Deng, Nan Ma, Guoying Wang   +7 more
wiley   +1 more source