Results 181 to 190 of about 48,159 (229)

Elevated Polyreactive Immunoglobulin G in Immune‐Mediated Liver Injuries With the Need for Immunosuppressive Therapy

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Background & Aims The distinction of drug‐induced liver injury (DILI), drug‐induced autoimmune‐like hepatitis (DI‐ALH), and autoimmune hepatitis (AIH) can be challenging due to overlapping clinical characteristics. Recently, polyreactive immunoglobulin G (pIgG) was identified as a novel biomarker in AIH.
Theresa Kirchner, George N. Dalekos, Kalliopi Zachou, Mercedes Robles‐Díaz, Raúl J. Andrade, Marcial Sebode, Ansgar Lohse, Maciej K. Janik, Piotr Milkiewicz, Mirjam Kolev, Nasser Semmo, Tony Bruns, Tom Jg. Gevers, Benedetta Terziroli Beretta‐Piccoli, Heiner Wedemeyer, Elmar Jaeckel, Richard Taubert, Bastian Engel, pIgG study group   +18 more
wiley   +1 more source

Systemic Sclerosis in a Seven-Year-Old Girl Responding to Mycophenolate Mofetil: A Case Report. [PDF]

Cureus
Alwadai M, Almusaad H, Yusuf R, Almutawa R, Albanna S.   +4 more
europepmc   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 633-638, March 2026.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Low-dose rituximab followed by mycophenolate mofetil for steroid-dependent/frequently relapsing nephrotic syndrome in children: a case series. [PDF]

Front Pharmacol
Song J, Chang H, Lin Y, Shan C, Liu J, Zhang R, Nie N, Bai C, Gao S, Zhang Q, Wang D.   +10 more
europepmc   +1 more source

Safety of Immune Checkpoint Inhibitors in Cancer Patients With Preexisting Autoimmune Vasculitis

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Immune checkpoint inhibitors (ICIs) are effective cancer therapies but often cause serious immune‐related adverse events (irAEs). Patients with preexisting autoimmune diseases, including vasculitis, are excluded from trials. We aimed to evaluate the frequency, severity, and outcomes of vasculitis flares and irAEs in this population.
Juan Sevillano, Noha Abdel‐Wahab, Yixuan Zhou, Juan I. Ruiz, Maria E. Suarez‐Almazor   +4 more
wiley   +1 more source

Sirolimus and Cyclosporine With Post-Transplant Cyclophosphamide or Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis in Unrelated Donor Hematopoietic Cell Transplantation. [PDF]

J Clin Oncol
Ueda Oshima M, Vo PT, Boeckh M, Bouvier ME, Carpenter PA, Mielcarek M, Petersdorf EW, Storb R, Gooley T, Sandmaier BM.   +9 more
europepmc   +1 more source

Anti‐CD146 Autoantibodies: The First Biologic Markers Associated With Occupational Exposure in Systemic Sclerosis

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Systemic sclerosis (SSc) is a severe autoimmune disease, with occupational exposure being a significant risk factor. Because CD146 was recently identified as a driver of fibrosis in SSc through regulation of the Wnt/reactive oxygen species interplay, we hypothesized that it is a major autoimmune target in this disease. Methods We developed an
Julien Bermudez, Xavier Heim, Elise Kaspi, Charlotte Reytier, Abdelouahab Beziane, Robin Arcani, Audrey Benyamine, Brigitte Granel, Antoine Villa, Marcel Blot‐Chabaud, Erwan Dumontet, Christophe Paris, Alain Lescoat, Valérie Lecureur, Nathalie Bardin   +14 more
wiley   +1 more source

Arrhythmia as a Possible Complication of Mycophenolate Mofetil in Systemic Sclerosis: A Case Report. [PDF]

Case Rep Med
Moradi Z, Ardestani V, Tamartash Z, Karimi E, Kavosi H.   +4 more
europepmc   +1 more source

Distinct by Design: Unraveling the Unique Clinical and Transcriptomic Identity of Juvenile Scleromyositis Overlap Compared to Juvenile Systemic Sclerosis and Juvenile Dermatomyositis: Implications for Care and Pathogenesis

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective To characterize clinical and transcriptomic differences in juvenile scleromyositis overlap (jOverlap) compared to juvenile systemic sclerosis (jSSc) and juvenile dermatomyositis (JDM), focusing on autoantibody profiles, organ involvement, treatment, and peripheral blood gene expression.
Amanda D. Robinson, Clare E. Pain, Gabrielle A. Morgan, Anwesha Sanyal, Srilakshmi Chaparala, Lauren M. Pachman, Kathryn S. Torok   +6 more
wiley   +1 more source

Regression of hepatic fibrosis in gamma-irradiated rats by mycophenolate mofetil: potential role of Egr-1. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Galal SM, Mostafa DM, El Kiki SM.
europepmc   +1 more source