Results 11 to 20 of about 48,159 (229)

Therapeutic effects of topical Mycophenolate mofetil on hydroquinone-induced depigmentation in Guinea pigs and mice [PDF]

Annals of Medicine
Background Vitiligo is a depigmentation disorder with an undefined specific pathogenesis, with the autoimmune theory being a prominent etiology. Mycophenolate mofetil (MMF), a novel immunosuppressant, selectively inhibits inosine 5-monophosphate ...
Yuan Guo, Yi-fei Yang, Yanhua-Li, Yun Zhang, Haixia-Shi   +4 more
doaj   +2 more sources

Evaluation of neutropenia secondary to mycophenolate mofetil associated with valganciclovir in liver transplant patients [PDF]

Farmacia Hospitalaria, 2021
Objective: Immunosuppressive drugs are necessary to avoid or reduce the risk of rejection of transplanted organs. The immunosuppression generated may result in these patients needing antibiotics and antivirals to be prescribed to them in conjunction ...
Alejandro Ferrer-Machín, Martín Vera-Cabrera, Inmaculada Plasencia-García, Antonia Moreno-García, Lina I. Pérez-Méndez, Javier Merino-Alonso   +5 more
doaj   +1 more source

Thromboelastometry assessment of mycophenolate mofetil effect on thrombotic risk in dogs with primary and secondary immune-mediated hemolytic anemia and by Erhlichia canis infection [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021
This study aimed to identify, by means of thromboelastometry assessment, altered thrombotic risk in dogs with primary and secondary IMHA by E. canis infection after initiating the immunosuppressive therapy with mycophenolate mofetil.
T.G. Gorenstein, F.V.R. Portilho, N.P. Calobrizi, D.S. Gonçalves, A.C. Paes, R.K. Takahira   +5 more
doaj   +1 more source

Analysis of the Clinical Effects of the Combination of Mycophenolate Mofetil with Either Tacrolimus or Cyclophosphamide [PDF]

Clinics, 2020
OBJECTIVES: Here, we aimed to compare the clinical effects of mycophenolate mofetil combined with either tacrolimus or with cyclophosphamide on lupus nephritis (LN) and to analyze their influence on the expression of cystatin C and on transforming growth
Xuebing Zhang, Pei Liu, Zhen Zhang
doaj   +1 more source

Effects of immunosuppression with tacrolimus and mycophenolate mofetil on renal histology and function in single kidney rats submitted to ischemia and reperfusion [PDF]

Acta Cirúrgica Brasileira, 2015
PURPOSE: To evaluate renal histological changes and renal function in single kidney rats submitted to renal ischemia-reperfusion and to immunosuppression with tacrolimus and mycophenolate-mofetil.
Paulo Henrique Goulart Fernandes Dias, Gabriel Augusto Oliveira, Fernando Goulart Fernandes Dias, Regina de Paula Xavier Gomes, Renato Tambara Filho, Rogério de Fraga   +5 more
doaj   +2 more sources

Refractory pemphigus vulgaris treated with rituximab and mycophenolate mofetil [PDF]

Anais Brasileiros de Dermatologia, 2014
The main treatment for pemphigus vulgaris are systemic corticosteroids and immunosuppressive agents, but due to adverse reactions and therapeutic failure, new drugs such as rituximab and mycophenolate mofetil have been used.
Stephanie Del Rio Navarrete Biot, Joanna Pimenta de Araujo Franco, Ricardo Barbosa Lima, Henrique Novo Costa Pereira, Luiz Paulo José Marques, Carlos José Martins   +5 more
doaj   +1 more source

Phase II, multi-center, open-label, single-arm clinical trial evaluating the efficacy and safety of Mycophenolate Mofetil in patients with high-grade locally advanced or metastatic osteosarcoma (ESMMO): rationale and design of the ESMMO trial

BMC Cancer, 2020
Background Clinical outcomes of patients with osteosarcoma remain unsatisfactory, with little improvement in a 5-year overall survival over the past three decades.
Nut Koonrungsesomboon, Nuttapong Ngamphaiboon, Natavudh Townamchai, Pimpisa Teeyakasem, Chaiyut Charoentum, Pimlak Charoenkwan, Rungrote Natesirinilkul, Lalita Sathitsamitphong, Touch Ativitavas, Parunya Chaiyawat, Jeerawan Klangjorhor, Suradej Hongeng, Dumnoensun Pruksakorn   +12 more
doaj   +1 more source

Mycophenolate mofetil versus cyclophosphamide plus in patients with connective tissue disease-associated interstitial lung disease: Efficacy and safety analysis

Open Medicine, 2023
The decision for definitive therapy for the treatment of patients with connective tissue disease-associated interstitial lung disease (CTD-ILD) is difficult.
Wang Pengfei, Zhang Li, Guo Qian, Zhao Lifen, Hao Yanyan   +4 more
doaj   +1 more source

Influence of mycophenolate mofetil dosage and plasma levels on the occurrence of chronic lung allograft dysfunction in lung transplants: a retrospective cohort analysis

Swiss Medical Weekly, 2022
INTRODUCTION: Development of chronic lung allograft dysfunction is a limiting factor for post-lung transplant survival. We evaluated whether the dose of the immunosuppressant mycophenolate mofetil or plasma concentrations of the active metabolite ...
Carolin Steinack, Philipp Saurer, Fiorenza Gautschi, René Hage, Gernot Ortmanns, Macé M. Schuurmans, Thomas Gaisl   +6 more
doaj   +1 more source

Steroid resistant focal segmental glomerulosclerosis: effect of arterial hyalinosis on outcome: single center study

Romanian Journal of Internal Medicine, 2021
Background. Few data with adequate evidence exists as regards the effect of Cyclosporine (CsA) and mycophenolate mofetil (MMF) on pathological prognostic parameters in patients with steroid resistant focal segmental glomerulosclerosis (FSGS). The purpose
Soliman Amin R., Maamoun Hoda, Soliman Haytham, Ahmed Rabab Mahmoud   +3 more
doaj   +1 more source