Results 91 to 100 of about 4,993,363 (331)
Journal of Pharmaceutical Health Care and Sciences, 2018 Background Mycophenolic acid (MPA) treatment requires therapeutic drug monitoring to improve the outcome after organ transplantation. The aim of this study was to compare two methods, a particle enhanced turbidimetric inhibition immunoassay (PETINIA) and
Masafumi Kikuchi +10 more
doaj +1 more source
Suppression of Hepatocellular Carcinoma by Mycophenolic Acid in Experimental Models and in Patients
Transplantation, 2019 Background. Tumor recurrence is a major complication following liver transplantation (LT) as treatment for hepatocellular carcinoma (HCC). Immunosuppression is an important risk factor for HCC recurrence, but conceivably may depend on the type of ...
Kan Chen +15 more
semanticscholar +1 more source
Geometric-algebraic approach to aqueous solutions of diprotic acids and its buffer mixtures [PDF]
arXiv, 2023 A closed-form analytical expression for $\ce{[H3O+]}$ has been obtained for aqueous solutions of diprotic acids and its soluble salts. This formula allows to calculate the pH of aqueous solutions of diprotic acids, their buffer solutions, and the titrations of these two by a strong base, from the values of p$K_1$, p$K_2$, and the effective ...
arxiv
Clinical Mass Spectrometry, 2017 Mycophenolic acid (MPA) is the active metabolite of the immunosuppressant drug mycophenolate mofetil (MMF), which is commonly prescribed after organ transplantation in conjunction with other immunosuppressants. MMF therapy is monitored to balance therapeutic efficacy with minimizing adverse effects associated with high serum concentrations.
Jesse C. Seegmiller +4 more
openaire +3 more sources
A mycophenolic acid derivative from the fungus Penicillium sp. SCSIO sof101
Natural Product Research, 2019 Mycophenolic acid (MPA) is a group of metabolite derived from several species of Penicillium, which shows potent bioactivity. In this study, a new derivative of MPA compound named penicacid D (1), was isolated from the marine derived fungus Penicillium ...
Xiao-Chen Song +8 more
semanticscholar +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Measurement of pre‐dose tacrolimus concentrations, also referred to as trough concentrations or C0 (in this paper the term C0 will be used), is the most frequently used parameter for therapeutic drug monitoring in patients after solid organ transplantation. C0 is relatively easy to obtain, and can be combined with other lab tests.
Teun van Gelder +4 more
wiley +1 more source
Large presence of carbonic acid in CO$_2$-rich aqueous fluids under Earth's mantle conditions [PDF]
Journal of Physical Chemistry Letters 10, 5135-5141 (2019), 2019 The chemistry of carbon in aqueous fluids at extreme pressure and temperature conditions is of great importance to Earth's deep carbon cycle, which substantially affects the carbon budget at Earth's surface and global climate change. At ambient conditions, the concentration of carbonic acid in water is negligible, so aqueous carbonic acid was simply ...
arxiv +1 more source
Regions of the T cell receptor alpha and beta chains that are responsible for interactions with CD3. [PDF]
, 1991 The T cell antigen receptor consists of the Ti alpha/beta heterodimer which recognizes antigen, and the associated CD3 chains, thought to be involved in signal transduction.
Tan, L, Turner, J, Weiss, A
core +1 more source
British Journal of Haematology, EarlyView.The use of rituximab as a pre‐emptive treatment in immune‐mediated thrombotic thrombocytopenic purpura (iTTP) is the current standard of care. However, for patients refractory to rituximab or for those with contraindication, further treatment guidelines are scarce.
Julia Weisinger +4 more
wiley +1 more source
Practical Laboratory Medicine, 2017 Background: For TDM of mycophenolate acid (MPA), the Roche Total Mycophenolic Acid® assay based on the inhibition of recombinant inosine monophosphate dehydrogenase (IMPDH) has been shown to be a simple and reliable alternative to chromatographic methods.
François Parant +2 more
doaj