Results 91 to 100 of about 24,385 (265)

Duplicate Prescription Patterns in Patients With Substance Use Disorders

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT This study sought to investigate the frequency and characteristics of duplicate prescriptions (DPs) in psychiatric inpatients with substance use disorders using a DP classification that differentiates between appropriate DPs (ADPs) and potentially inappropriate DPs (PIDPs). The study was conducted as a monocentric retrospective cross‐sectional
Johannes Heck, Benjamin Krichevsky, Martin Schulze Westhoff, Konstantin Fritz Jendretzky, Martin Klietz, Stephan Greten, Alexander Glahn, Stefan Bleich, Sebastian Schröder   +8 more
wiley   +1 more source

Impact of glucuronide interferences on therapeutic drug monitoring of posaconazole by tandem mass spectrometry [PDF]

, 2010
Background: Posaconazole is a novel antifungal drug for oral application intended especially for therapy of invasive mycoses. Due to variable gastrointestinal absorption, adverse side effects, and suspected drug-drug interactions, therapeutic drug ...
Burghardt, Stephan, Krueger, Ralf, Lackner, Karl J., Vogelsberger, Rita, Vogeser, Michael   +4 more
core   +1 more source

Electrochemical Biosensor for Rapid Detection of Acute Rejection in Kidney Transplants

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
A low‐cost, rapid electrochemical immunosensor coated with a novel antifouling nanocomposite enables single‐step, dual‐biomarker profiling directly from unprocessed urine. Application in a clinical study shows accurate discrimination of acute rejection in kidney transplants from other acute kidney injuries via machine learning.
Rohit Gupta, Nikolaos Salaris, Ashish Kalkal, Fernando Yuen Chang, Maryam Javed, Azhar Ali Khan, Priya Mandal, Stavroula Balabani, Reza Motallebzadeh, Manish K. Tiwari   +9 more
wiley   +1 more source

Estudo da relação entre o polimorfismo c.98T>C do gene UGT1A9 e níveis plasmáticos de ácido micofenólico em pacientes transplantados renais [PDF]

, 2015
After the proceeding of a transplant, it is of huge concem the use of all therapeutic resource available in order to prevent graft rejection. The incidence and severity of acute rejection have been reduced along time due to the development of new ...
Ruschel, Lizania Rodrigues
core  

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 241-254, January 2026.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

Effects of Inosine-5′-monophosphate Dehydrogenase (IMPDH/GuaB) Inhibitors on Borrelia burgdorferi Growth in Standard and Modified Culture Conditions

Microorganisms
Borrelia burgdorferi’s inosine-5′-monophosphate dehydrogenase (IMPDH, GuaB encoded by the guaB gene) is a potential therapeutic target. GuaB is necessary for B. burgdorferi replication in mammalian hosts but not in standard laboratory culture conditions.
Eric L. Siegel, Connor Rich, Sanchana Saravanan, Patrick Pearson, Guang Xu, Stephen M. Rich   +5 more
doaj   +1 more source

Mycophenolic-acid/prednisone/tacrolimus

, 2021

openalex   +2 more sources

Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. [PDF]

, 2018
Bioactive natural products have evolved to inhibit specific cellular targets and have served as lead molecules for health and agricultural applications for the past century1-3.
Bat-Erdene, Undramaa, Gan, Jianhua, Jacobsen, Steven E, Liu, Qikun, Nguyen, Calvin, Tang, Yi, Yan, Yan, Yuan, Shuguang, Zang, Xin, Zhou, Jiahai   +9 more
core  

Development of an UPLC-MS/MS method for the analysis of mycotoxins in rumen fluid with and without maize silage emphasizes the importance of using matrix-matched calibration [PDF]

, 2019
Ruminants are less susceptible to the effects of mycotoxins than monogastric animals as their rumen microbiota are claimed to degrade and/or deactivate at least some of these toxic compounds. However, the mycotoxin degradation is not well-known yet.
Croubels, Siska, De Baere, Siegrid, Debevere, Sandra, Fievez, Veerle, Haesaert, Geert, Rychlik, Michael   +5 more
core   +1 more source

Development of an HPLC method using relative molar sensitivity for the measurement of blood concentrations of nine pharmaceutical compounds

Journal of Pharmaceutical Health Care and Sciences
We developed a reliable high-performance liquid chromatographic analysis method using a relative molar sensitivity (RMS) technique that does not require an authentic, identical reference analyte material to quantify blood serum carbamazepine, phenytoin ...
Takashi Ohtsuki, Yi Huang, Ayane Kamiya, Yuki Nakayama, Miyuki Matsushita, Satoru Morikawa, Hiroshi Matsufuji   +6 more
doaj   +1 more source