Results 91 to 100 of about 21,722 (233)

Early Mycophenolate Mofetil Combination Therapy as an Effective Approach for Immune‐Related Hepatitis Induced by Immune Checkpoint Inhibitors in Patients With Solid Tumor

Cancer Medicine, Volume 15, Issue 3, March 2026.
Our study highlights the benefits of early use of mycophenolate mofetil (MMF) for patients with immune‐related hepatitis requiring systemic steroids. This may provide guidance on the appropriate use of MMF in terms of its efficacy and safety. ABSTRACT Background Immune‐related hepatitis (ir‐hepatitis) is an immune‐related adverse event that can be ...
Yukiko Shimoda Igawa, Tatsuya Yoshida, Jun Sato, Yuri Yoshinami, Yukiko Hibino, Takamichi Arima, Yuta Maruki, Hirokazu Shoji, Kenjiro Namikawa, Kazuki Sudo, Yoshitaka Honma, Natsuko Okita, Hironobu Hashimoto, Naoya Yamazaki, Takuji Okusaka, Kan Yonemori, Noboru Yamamoto, Yuichiro Ohe, Ken Kato   +18 more
wiley   +1 more source

Effects of Inosine-5′-monophosphate Dehydrogenase (IMPDH/GuaB) Inhibitors on Borrelia burgdorferi Growth in Standard and Modified Culture Conditions

Microorganisms
Borrelia burgdorferi’s inosine-5′-monophosphate dehydrogenase (IMPDH, GuaB encoded by the guaB gene) is a potential therapeutic target. GuaB is necessary for B. burgdorferi replication in mammalian hosts but not in standard laboratory culture conditions.
Eric L. Siegel, Connor Rich, Sanchana Saravanan, Patrick Pearson, Guang Xu, Stephen M. Rich   +5 more
doaj   +1 more source

Chemical Constituents of Taxodium mucronatum (Cupressaceae) and Some of Its Endophytic Fungi, and Their In Silico and In Vitro Evaluations as SARS‐CoV‐2 Inhibitors and as Cytotoxic Agents

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Abietanes, pimaranes and cycloartanes were characterized from different plant tissues of Taxodium mucronatum. Curvularins, mycophenolic acids and ergosterol were isolated from some fungal endophytes. The isolated compounds were in silico and in vitro evaluated as antiviral and cytotoxic agents.
Nadia Mendoza, Olivia Pérez‐Valera, Antonio Nieto‐Camacho, María Teresa Ramírez‐Apan, Marcela Guadalupe Téllez‐Martínez, Eleazar M. Escamilla‐Silva, Guillermo Delgado   +6 more
wiley   +1 more source

New Clox Systems for rapid and efficient gene disruption in Candida albicans [PDF]

, 2014
Acknowledgements: We are grateful to Janet Quinn, Lila Kastora, Joanna Potrykus, Michelle Leach, and others for sharing their experiences with the Clox cassettes.
Ballou, Elizabeth R, Bohovych, Iryna, Brown, Alistair J P, Childers, Delma S, Gow, Neil A. R., Odds, Frank C, Shahana, Shahida   +6 more
core   +4 more sources

A Case of Intermittent Fever a Decade After Renal Transplantation

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Disseminated histoplasmosis is a potentially serious complication after organ transplantation; however, its occurrence is rare, even in endemic regions. Diagnosis can be challenging, particularly in patients with nonspecific symptoms such as intermittent fever or lethargy.
Merazul Islam Ony, Baris Afsar, Bahar Bastani   +2 more
wiley   +1 more source

Development of an HPLC method using relative molar sensitivity for the measurement of blood concentrations of nine pharmaceutical compounds

Journal of Pharmaceutical Health Care and Sciences
We developed a reliable high-performance liquid chromatographic analysis method using a relative molar sensitivity (RMS) technique that does not require an authentic, identical reference analyte material to quantify blood serum carbamazepine, phenytoin ...
Takashi Ohtsuki, Yi Huang, Ayane Kamiya, Yuki Nakayama, Miyuki Matsushita, Satoru Morikawa, Hiroshi Matsufuji   +6 more
doaj   +1 more source

Mycophenolate-mofetil/mycophenolic-acid [PDF]

Reactions Weekly, 2021
openaire   +1 more source

Mycophenolic Acid [PDF]

Reactions Weekly, 2020
  +4 more sources

Estudo da relação entre o polimorfismo c.98T>C do gene UGT1A9 e níveis plasmáticos de ácido micofenólico em pacientes transplantados renais [PDF]

, 2015
After the proceeding of a transplant, it is of huge concem the use of all therapeutic resource available in order to prevent graft rejection. The incidence and severity of acute rejection have been reduced along time due to the development of new ...
Ruschel, Lizania Rodrigues
core  

Individualized immunosuppression in transplant patients: potential role of pharmacogenetics. [PDF]

, 2012
The immunosuppressive drugs used to prevent the rejection of transplanted organs have a narrow therapeutic index. Under treatment results in episodes of rejection leading to either damage or loss of the organ. Over immunosuppression increases the risk of
Abboudi, H, Macphee, IA
core   +2 more sources