Results 101 to 110 of about 21,722 (233)
JEADV Clinical Practice, Volume 5, Issue 1, Page 101-116, March 2026.ABSTRACT Background Biologics and Janus kinase inhibitors (JAKi) are two advanced systemic treatment options for patients with atopic dermatitis (AD). The decision to initiate one of these therapies is complex and may be driven by many factors.
Eric L. Simpson +12 more
wiley +1 more source
MedComm, Volume 7, Issue 3, March 2026.Female‐specific renal GluCer accumulation disrupts mitochondrial quality control via a conserved purine‐mTORC1 pathway, triggering a wave of uremic toxins into the systemic circulation that constitutes a female‐biased vulnerability toward renal‐driven multiorgan senescence.
Zhen Ni +18 more
wiley +1 more source
In vitro dissolution kinetic for mycophenolic acid derivatives tablets
Brazilian Journal of Pharmaceutical Sciences, 2013 Mycophenolate mofetil (MMF) and mycophenolate sodium (MPS) are an ester and a salt of mycophenolic acid. They have different kinetic in vivo characteristics due to differences in molecular structures, physicochemical properties and formulations ...
André Lima de Oliveira Costa +5 more
doaj +1 more source
PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana +4 more
wiley +1 more source
De novo GTP biosynthesis is critical for virulence of the fungal pathogen Cryptococcus neoformans.
PLoS Pathogens, 2012 We have investigated the potential of the GTP synthesis pathways as chemotherapeutic targets in the human pathogen Cryptococcus neoformans, a common cause of fatal fungal meningoencephalitis.
Carl A Morrow +11 more
doaj +1 more source
Small Science, Volume 6, Issue 3, March 2026.Current treatments for severe lupus nephritis are limited by side effects due to poor drug targeting. This review explores how smart nanomaterials—like liposomes and biomimetic carriers—can precisely deliver drugs to overactive immune cells and the kidneys. These nanotherapeutics enhance efficacy, reduce toxicity, and enable combination strategies. The
Cheng Zhou +6 more
wiley +1 more source
Insights Into Gut Barrier Dysfunction and Metabolic Alterations in Mycophenolate‐Induced Enteropathy
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.ABSTRACT Mycophenolic acid (MPA) is a widely used immunosuppressant whose use is often limited by gastrointestinal toxicity. Gut bacterial hydrolysis of liver‐derived MPA glucuronides increases local exposure to MPA, potentially impairing epithelial barrier function and cellular metabolism.
Clarisse Brossier +6 more
wiley +1 more source
Alemtuzumab Induction in Septuagenarians Undergoing Deceased Donor Kidney Transplantation
Clinical Transplantation, Volume 40, Issue 3, March 2026.ABSTRACT Introduction The anti‐CD52 monoclonal antibody alemtuzumab is used as an induction agent in kidney transplantation (KT) but remains understudied in septuagenarian recipients. The study purpose was to analyze the safety and efficacy of single‐dose alemtuzumab induction in septuagenarian deceased donor (DD) KT recipients.
David I. Harriman +6 more
wiley +1 more source
Scientific ReportsHuman Metapneumovirus (HMPV) is a leading cause of respiratory tract infections worldwide, with no approved antiviral treatments or vaccines currently available.
Pallavi Mosale Shanthappa +2 more
doaj +1 more source
Clinical Transplantation, Volume 40, Issue 3, March 2026.ABSTRACT Introduction Although advanced age is no longer a contraindication for renal transplantation, real‐world data on elderly transplant recipients remain limited. Methods This multicenter, prospective study enrolled de novo kidney transplant recipients aged 60 years or older receiving once‐daily tacrolimus immunosuppression, following recovery of ...
Amado Andrés +24 more
wiley +1 more source