Results 101 to 110 of about 24,385 (265)
Journal of Viral Hepatitis, Volume 33, Issue 1, January 2026.ABSTRACT Organ transplant recipients are at high risk of developing chronic infection when exposed to hepatitis E virus (HEV), which can rapidly progress to liver fibrosis and cirrhosis. Macrophages play a key role in the response to the infection and disease progression.
Jiahua Zhou +4 more
wiley +1 more source
No Evidence of a Drug-Drug Interaction Between Letermovir (MK-8228) and Mycophenolate Mofetil [PDF]
, 2015 Introduction: Letermovir (MK-8228) is a potent, oncedaily inhibitor of the cytomegalovirus (CMV) terminase complex that is being developed for the prophylaxis of CMV infection in transplant patients. This study evaluated the pharmacokinetic interactions,
Badshah, C. +9 more
core +2 more sources
JAK Inhibitors as a Novel Approach to Autoimmune Bullous Diseases: A Review
Dermatologic Therapy, Volume 2026, Issue 1, 2026.Autoimmune bullous diseases (AIBDs) are a group of chronic disorders characterized by blister formation resulting from abnormal immune responses. Janus kinase (JAK) inhibitors have emerged as promising therapeutic agents for AIBDs. This review discusses the use of JAK inhibitors—such as upadacitinib, baricitinib, tofacitinib, and abrocitinib, among ...
Olga Olisova +9 more
wiley +1 more source
Pitfalls in measuring the endocannabinoid 2-arachidonoyl glycerol in biological samples [PDF]
, 2007 Background: The endocannabinoid 2-arachidonoyl glycerol (2-AG) undergoes spontaneous isomerization to biologically inactive 1-AG. This effect has not been adequately addressed in previous studies that reported 2-AG concentrations in biological samples ...
Schelling, Gustav, Vogeser, Michael
core +1 more source
In vitro dissolution kinetic for mycophenolic acid derivatives tablets
Brazilian Journal of Pharmaceutical Sciences, 2013 Mycophenolate mofetil (MMF) and mycophenolate sodium (MPS) are an ester and a salt of mycophenolic acid. They have different kinetic in vivo characteristics due to differences in molecular structures, physicochemical properties and formulations ...
André Lima de Oliveira Costa +5 more
doaj +1 more source
Effects of mycophenolic acid on human renal proximal and distal tubular cells in vitro [PDF]
, 2000 Patrick C. Baer +4 more
openalex +1 more source
De novo GTP biosynthesis is critical for virulence of the fungal pathogen Cryptococcus neoformans.
PLoS Pathogens, 2012 We have investigated the potential of the GTP synthesis pathways as chemotherapeutic targets in the human pathogen Cryptococcus neoformans, a common cause of fatal fungal meningoencephalitis.
Carl A Morrow +11 more
doaj +1 more source
Individualization of Immunosuppressive Therapy after Solid Organ Transplantation [PDF]
, 2014 __Abstract__ When an individual’s kidneys fail, there are three treatment options: hemodialysis, peritoneal dialysis or kidney transplantation. A successful kidney transplantation results in the best patient survival and a better quality of life ...
Bouamar, R. (Rachida)
core +1 more source