Amino acid metabolism conflicts with protein diversity [PDF]
The twenty protein coding amino acids are found in proteomes with different relative abundances. The most abundant amino acid, leucine, is nearly an order of magnitude more prevalent than the least abundant amino acid, cysteine. Amino acid metabolic costs differ similarly, constraining their incorporation into proteins.
arxiv
Structure and Mechanism of Inosine Monophosphate Dehydrogenase in Complex with the Immunosuppressant Mycophenolic Acid [PDF]
Michael D. Sintchak+7 more
openalex +1 more source
Total synthesis of mycophenolic acid [PDF]
Ricardo A. de la Cruz+3 more
openalex +1 more source
Mycotoxins and Other Secondary Metabolites Produced in vitro by Penicillium paneum Frisvad and Penicillium roqueforti Thom Isolated from Baled Grass Silage in Ireland [PDF]
Auerbach H.+45 more
core +2 more sources
Introduction: Mycophenolic acid(MPA), a fungal mycotoxin, is produced by Penicillium brevicompactum and is used for the synthesis of immunosuppressive drugs in pharmaceutical industries.
M Afshari+8 more
doaj
Pharmacodynamic assessment of mycophenolic acid-induced immunosuppression by measuring IMP dehydrogenase activity [PDF]
Loralie J. Langman+2 more
openalex +1 more source
(1) Background: Food and feed safety legislation does not concern all the mycotoxins generated by Penicillium and Aspergillus spp. Certain mycotoxins, including mycophenolic acid (MPA), cyclopiazonic acid (CPA), penicillic acid (PA), roquefortine C (ROQ ...
Dritan Topi+4 more
doaj +1 more source
Isolation and Characterization of Mycophenolic Acid-resistant Mutants of Inosine-5′-monophosphate Dehydrogenase [PDF]
Thalia A. Farazi+4 more
openalex +1 more source
Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. [PDF]
Bioactive natural products have evolved to inhibit specific cellular targets and have served as lead molecules for health and agricultural applications for the past century1-3.
Bat-Erdene, Undramaa+9 more
core
Hepatic growth effects of methylprednisolone, azathioprine, mycophenolic acid, and mizoribine [PDF]
Azzarone, A+3 more
core +1 more source