Results 121 to 130 of about 204,618 (368)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Mycoplasma pneumoniae is a type of bacteria that can cause several different types of infection including chest colds and pneumonia (lung infection).
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Genotyping of Pathogenic Mycoplasma bovis Isolated from Cattle in Kafr El-Sheikh Province, Egypt
, 2018 Mycoplasma bovis is one of the important pathogens in mycoplasma types that cause disease in cattle. The young calves from one to four months of age are most likely to develop pneumonia caused by M. bovis. In this study, we isolated M.
Mohamed M. Hassan +3 more
core +1 more source
Mycoplasma pneumoniae: Atypical Pathogen in Community Acquired Pneumonia
, 2020 Mycoplasma pneumoniae is a one of most common reasons of respiratory tract infections in both adolescents and children with severity ranged from moderate to high. Many facts in the previous years regarding infections were induced via this organism having
Abdul-Rahman Mamdouh Mohammad +2 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
, 2006 Mycoplasma mycoides subsp. capri and Mycoplasma mycoides subsp. mycoides LC can be combined into one taxon on the basis of several contributions on both DNA sequence and protein analyses reported in the literature.
Joachim Frey +7 more
core +1 more source
Mycoplasma hyopneumoniae pathogenicity: the known and the unknown
, 2020 This chapter discusses the current knowledge of Mycoplasma hyopneumoniae virulence, sequence of pathogenesis, adhesion, candidate virulence factors, immune modulation and Mycoplasma host interaction. A simple model of M.
Kuhnert, Peter +3 more
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