Results 111 to 120 of about 204,618 (368)

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Differential innate immune responses induced by Mycoplasma hyopneumoniae and Mycoplasma hyorhinis in various types of antigen presenting cells.

, 2020
Mycoplasma (M.) hyopneumoniae is the etiological agent of enzootic pneumonia in pigs and is closely related to M. hyorhinis, which can be isolated from the healthy mucosal surfaces of the upper respiratory tract. In rare cases it can also cause arthritis
Trueb, Bettina S., Summerfield, Artur, Kuhnert, Peter, Auray, Gaël, Braun, Roman Othmar   +4 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report

Frontiers in Pediatrics
The mortality of pulmonary embolism in children is high, and there is no standardized treatment protocol. We present a case of successful treatment of Mycoplasma pneumoniae (M pneumoniae) with pulmonary embolism in a child using rivaroxaban and ...
Fang Xiaoqian, Lu Hemin
doaj   +1 more source

An easy α-glycosylation methodology for the synthesis and stereochemistry of mycoplasma α-glycolipid antigens

Beilstein Journal of Organic Chemistry, 2012
Mycoplasma fermentans possesses unique α-glycolipid antigens (GGPL-I and GGPL-III) at the cytoplasm membrane, which carry a phosphocholine group at the sugar primary (6-OH) position.
Yoshihiro Nishida, Yuko Shingu, Yuan Mengfei, Kazuo Fukuda, Hirofumi Dohi, Sachie Matsuda, Kazuhiro Matsuda   +6 more
doaj   +1 more source

Identification and Characterization of Nasal Polyposis and Mycoplasma Superinfection by Scanning Electron Microscopy and Nasal Cytology with Optical Microscopy: A Case Report

Diagnostics, 2019
Nasal polyposis is characterized by benign, non-cancerous and painless growths originating in the tissue of the nasal cavities and paranasal sinuses. Polyps arise from chronic inflammation due to asthma, recurrent infections, allergies, drug sensitivity ...
Arturo Armone Caruso, Veronica Viola, Salvatore Del Prete, Sabato Leo, Daniela Marasco, Andrea Fulgione, Daniele Naviglio, Monica Gallo   +7 more
doaj   +1 more source

Mycoplasma pneumoniae infection and neurological complications. [PDF]

, 1979
G. E. D. Urquhart
openalex   +1 more source

Waterfowl mycoplasma putative prophages

, 2021
Áron Botond Kovács
openalex   +1 more source

Monoklonális antitest Mycoplasma szennyeződésének vizsgálata real-time PCR módszerrel

, 2019
A dolgozat témája a gyógyszeriparban jelenlévő esetleges Mycoplasma szennyeződés kimutatása az alkalmazott sejtvonalakból. A mérés során egy qPCR technológián alapuló gyors kimutatási rendszert alkalmazom, ami a baktérium genomban található konzervált ...
Gáll-Kiss, Beáta
core  

Mycoplasma leachii sp. nov. as a new species designation for Mycoplasma sp. bovine group 7 of Leach, and reclassification of Mycoplasma mycoides subsp. mycoides LC as a serovar of Mycoplasma mycoides subsp. capri

, 2009
The Mycoplasma mycoides cluster consists of six pathogenic mycoplasmas causing disease in ruminants, which share many genotypic and phenotypic traits. The M. mycoides cluster comprises five recognized taxa: Mycoplasma mycoides subsp.
Vilei, Edy M., Manso-Silvan, Lucia, Manso-Silván, L, Sachse, K., Sachse, Konrad, Vilei, E, Thiaucourt, F, Djordjevic, SP, Sachse, K, Vilei, E.M., Frey, Joachim, Frey, J, Vilei, EM, Thiaucourt, F., Thiaucourt, François, Manso-Silvan, L., Frey, J., Djordjevic, S.P., Djordjevic, S   +18 more
core   +1 more source