Results 91 to 100 of about 195,622 (313)

Evidence that UGA is read as a tryptophan codon rather than as a stop codon by Mycoplasma pneumoniae, Mycoplasma genitalium, and Mycoplasma gallisepticum. [PDF]

, 1990
Molecular cloning and sequencing showed that Mycoplasma gallisepticum, like Mycoplasma capricolum, contains both tRNA(UCA) and tRNA(CCA) genes, while Mycoplasma pneumoniae and Mycoplasma genitalium each appear to have only a tRNA(UCA) gene.
Hu, P C, Loechel, S, Ho, K C, Inamine, J M   +3 more
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Genome Sequence of Mycoplasma feriruminatoris sp. nov., a Fast-Growing Mycoplasma Species

, 2023
Members of the “Mycoplasma mycoides cluster” represent important livestock pathogens worldwide. We report the genome sequence of Mycoplasma feriruminatoris sp.
Vilei, Edy M., Frey, Joachim, Jores, Joerg, Drabek, Elliott, Giglio, Michelle, Nadendla, Suvarna, Santana-Cruz, Ivette, Fischer, Anne   +7 more
core   +1 more source

Mycoplasma pneumoniae: re-emergence and beyond.

Agyeman and Aebi are Members of European Society of Clinical Microbiology and Infectious Diseases Study Group for Mycoplasma and Chlamydia Infections (ESGMAC) Mycoplasma pneumoniae Surveillance (MAPS) study groupDepartment of ...
European Society of Clinical Microbiology and Infectious Diseases Study Group for Mycoplasma and Chlamydia Infections (ESGMAC) Mycoplasma pneumoniae Surveillance (MAPS) study group, Meyer Sauteur, Patrick M   +1 more
core   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

CA27 neutralizes mycoplasma infection.

, 2016
(A) Mycoplasmas (1x105 CFU/ml) were incubated with PBS (positive control), boiled CA27 (negative control, 3 μg/ml), or active CA27 (1–3 μg/ml), added to Huh7 cells, and then cultured for 2 days.
Dae Shick Kim (421861), Young-Joo Jang (3609293), Hyun Min Lee (3609296), Min Kyu Kim (479520), Jaemin Jeong (3609290), Yu Ra Jo (3609287), Hee Jin Chang (398881), Hong Seo Choi (759363), Yangsoon Lee (262206), Won-Tae Kim (759362), Chun Jeih Ryu (759365), Dongho Choi (3609284)   +11 more
core   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Biochemical and serological characterization of Mycoplasma from bovine clinical mastitis in southwest and northern Nigeria

, 2010
The primary objective of this study was to isolate and characterize the mycoplasma species present in clinical cases of mastitic cows in Southwest and Northern Nigeria and to determine the prevalence of mycoplasma mastitis in dairy cows. Two hundred milk
Adetosoye, A. I., Amosun, E. A., Ajuwape, A. T. P.   +2 more
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Characteristics of the respiratory season in 2022—23 and 2023—24 according to data from the city children's hospital

Детские инфекции (Москва)
The end of the COVID-19 pandemic in the respiratory disease season of 2022—23 was characterized by an increase in the number of cases, a shift in the classic peaks of morbidity for various infections, and a predominance of influenza and respiratory ...
Е. М. Tolstova, М. А. Nikonova, О. V. Zaytseva, N. S. Zaitseva, Е. Е. Lokshina, М. V. Besedina, S. R. Kuzina, Е. V. Kulikova, Т. Yu. Belyaeva   +8 more
doaj   +1 more source