Results 81 to 90 of about 195,622 (313)

Exploration fonctionnelle du génome de mycoplasma agalactiae : recherche des facteurs de virulence en culture cellulaire [PDF]

, 2011
Mycoplasma agalactiae est l'agent étiologique de l'agalactie contagieuse des petits ruminants, maladie inscrite sur la liste de l'OIE. Le développement d'un système de criblage en culture cellulaire a permis de mener une étude à haut-débit des ...
Skapski, Agnès
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Economic Consequences of Biological Variation: The Case of Mycoplasma in Swine Herds [PDF]

We present an economic decision support model, based on a Bayesian network, for Mycoplasma infection in slaughter swine production. The model describes the various risk factors for Mycoplasma infection and their interactions.
Otto, Lars
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Análise proteômica de proteínas citoplasmáticas de Mycoplasma synoviae [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Biotecnologia, Florianópolis, 2010O Mycoplasma synoviae é um dos mais importantes patógenos de aves domésticas em todo o mundo ...
Menegatti, Angela Camila Orbem
core  

Mycoplasma pneumoniae infections, 11 countries in Europe and Israel, 2011 to 2016 [PDF]

, 2020
Background: Mycoplasma pneumoniae is a leading cause of community-acquired pneumonia, with large epidemics previously described to occur every 4 to 7 years. Aim: To better understand the diagnostic methods used to detect M.
Nir-Paz, Ran,, Georgakopoulou, Theano, Anestad, Gabriel,, Chalker, Victoria J., MacKenzie, Colin Rae,, Spiller, O Brad, Kese, Darja, Yandle, Zoe,, McMenamin, Jim, Moran, Joanne,, Bebear, Cecile,, Maltezou, Helena C.,, Froes, Filipe,, Dumke, Roger,, Vestrheim, Didrik F., Marques, Diogo Pereira,, Burns, Karen,, Giske, Christian,, Koliou, Maria,, Pereyre, Sabine,, Socan, Maja,, Michael-Gayego, Ayelet, Beeton, Michael L, Uldum, Soren A., Anestad, Gabriel, Reynolds, Arlene, Cano Portero, Rosa,, Cano-Portero, Rosa, Chalker, Victoria J.,, Froes, Filipe, Blystad, Hans,, Gullsby, Karolina, Havlickova, Martina, Havlickova, Martina,, Chlamydia Infections (ESGMAC) Mycoplasma pneumoniae subgroup, Emborg, Hanne-Dorthe, Zhang, Xu-Sheng, Fenech, Tanya Melillo,, Kese, Darja,, Reynolds, Arlene,, Loens, Katherine, Fenech, Tanya Melillo, Zhang, Xu-Sheng,, Beeton, Michael L.,, Emborg, Hanne-Dorthe,, Ieven, Margareta, Michael-Gayego, Ayelet,, Spiller, O. Brad,, The Escmid Study Group For Mycoplasma And Chlamydia Infections Esgmac Mycoplasma Pneumoniae Subgroup,, Koliou, Maria, Pereyre, Sabine, Bossuyt, Nathalie, Moses, Allon E., Voldstedlund, Marianne,, Banou, Kirkira,, Suarez Rodriguez, Berta, Lagrou, Katrien,, Georgakopoulou, Theano,, Spiller, O. Brad, Vestrheim, Didrik F.,, Ieven, Margareta,, McMenamin, Jim,, Socan, Maja, Maltezou, Helena C., ESCMID Study Group for Mycoplasma, Balla, Eszter, Uldum, Søren A, Moran, Joanne, Burns, Karen, Kyncl, Jan,, Santos Sanz, Sara,, Ternhag, Anders,, Lagrou, Katrien, Ternhag, Anders, Uldum, Soren A.,, Giske, Christian, Moses, Allon E.,, Banou, Kirkira, Uldum, Søren A., Dumke, Roger, Voldstedlund, Marianne, Bossuyt, Nathalie,, Bébéar, Cécile, Petridou, Evangelina, MacKenzie, Colin Rae, Nir-Paz, Ran, Connell, Jeff, Cano Portero, Rosa, Santos Sanz, Sara, Gullsby, Karolina,, Mitis, George,, Wisell, Karin Tegmark, The Escmid Study Group For Mycoplasma And Chlamydia Infections Esgmac Mycoplasma Pneumoniae Subgroup, -, Suarez Rodriguez, Berta,, Petridou, Evangelina,, Loens, Katherine,, Blystad, Hans, Yandle, Zoe, Marques, Diogo Pereira, Chalker, Victoria J, Balla, Eszter,, Kyncl, Jan, Connell, Jeff,, Beeton, Michael L., Wisell, Karin Tegmark,, ESCMID Study Group for Mycoplasma and Chlamydia Infections (ESGMAC) Mycoplasma pneumoniae sub-group, Mitis, George, Gullsby, K, Uldum, SA, Dumke, R, Pereyre, S, Nir-Paz, R, Ieven, M, Zhang, X-S, Loens, K, Bebear, C, Beeton, ML   +116 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Detection of Mycoplasma bovis in Pneumonic Calves

, 2019
Mycoplasma bovis is a major pathogen in respiratory diseases of calves and cause an excessive economic loses. The current study was a goal to diagnoses bovine Mycoplasma and chiefly M.
Mohammad T. Jaber Mayahi, Zahraa M. AL-Jumaa, Mohammad A. Hamad, Ammar M. Al-Aalim   +3 more
core   +1 more source

Scarlatiniform Rash Caused by Mycoplasma pneumoniae [PDF]

, 2020
Mycoplasma pneumoniae is a significant cause of acute respiratory disease in children and young adults. We describe a case of a 15-year-old boy who presented with an unusual scarlatiniform rash in the setting of a positive Mycoplasma pneumonia IgM but ...
Rahnama-Moghadam, Sahand, Mohammed, Arooj   +1 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source