Elevated Anti-Mycoplasma pneumoniae IgG Titers in Chronic Epipharyngitis: Insights Into Persistent Immune Dysregulation. [PDF]
Mogitate M, Matsuda S, Matsuda K.
europepmc +1 more source
RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo +10 more
wiley +1 more source
Analysis of early haematological warning indicators for drug-resistant <i>Mycoplasma pneumoniae</i> infection. [PDF]
Yang Y, Sun T, Fu C, Yan X.
europepmc +1 more source
This study identifies MZF1 as a core regulator of colon cancer via SnoN‐mediated TGF‐β suppression, proposes 10Panx Acetate as a targeted inhibitor, and validates MZF1/SnoN as prognostic markers for aggressive disease. ABSTRACT Colon cancer progression is associated with transcriptional and signaling abnormalities.
Siqi Sheng +9 more
wiley +1 more source
Emergence of Novel Macrolide-Resistant Mycoplasma pneumoniae Sequence Type 3 Subclades in Children after COVID-19 Pandemic, Taiwan. [PDF]
Hsieh YC +13 more
europepmc +1 more source
Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi +8 more
wiley +1 more source
Emergence of <i>Acholeplasma laidlawii</i> Infection in Ducks: Isolation and Colonization Potential. [PDF]
Lv J +6 more
europepmc +1 more source
A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu +3 more
wiley +1 more source
One Health Perspective of Mycoplasmas: Proposals for Standardizing In Vitro PK/PD Models of Human Mycoplasma Species by Referencing Veterinary Experiences. [PDF]
Wang N, Liu Y, Xiao L.
europepmc +1 more source

