Results 201 to 210 of about 195,622 (313)

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

Advanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu   +13 more
wiley   +1 more source

Conference on New and Re-Emerging Infectious Diseases

Emerging Infectious Diseases, 2004
Roberto Docampo
doaj   +1 more source

Mycoplasma Contamination Alters the Expression Profile of Pro-Inflammatory Cytokines by Human Innate Immune Cells. [PDF]

Cell Biochem Funct
Gogesch P, Kronhart S, Niles MA, Kochs G, Waibler Z, Anzaghe M.   +5 more
europepmc   +1 more source

Carbohydrate‐Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin‐Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM

Advanced Science, EarlyView.
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge, John S. Fossey, David Gonzalez Calatayud, Stephen E. Flower, Sabrina Wang, Hanna Aitessaid, Melita Tvardauskaite, Julia Dudzic, Max Jewell, Charareh Pourzand, Stanley W. Botchway, David Gurevich, Tony D. James, Sofia I. Pascu   +13 more
wiley   +1 more source

Feline haemotropic Mycoplasma spp. in Portugal: association with identifiable risk factors, clinical parameters and prognostic factors. [PDF]

Companion Anim Health Genet
Li W, Reisinho ATSC, Carvalho LMM.
europepmc   +1 more source

A Dual‐Mode In Situ EV‐miRNA Profiling Platform for Machine‐Learning‐Assisted Gastric Cancer Liquid Biopsy

Advanced Science, EarlyView.
An in situ dual‐mode platform integrates fusogenic liposomes with localized autocatalytic DNA circuits for plasma‐derived extracellular vesicle microRNA analysis. Following membrane fusion, target miRNAs trigger feedback‐assisted LECHA amplification inside intact vesicles, generating fluorescence and electrochemical outputs. Machine learning integrates
Wenbin Li, Rui Fan, Kun Xie, Jiehua Zhong, Yitong Zhu, Tingting Ji, Yuanyuan Qin, Shijin Peng, Yu Zhang, Yuhang Guo, Tiange Zhang, Chunchen Liu, Bo Li, Lei Zheng, Ye Zhang, Xiaohui Yan   +15 more
wiley   +1 more source

Clinical insights into Candidatus Mycoplasma haemominutum-associated anaemia in naturally infected cats: flea-associated risk and paradoxical clinicopathological findings. [PDF]

Ir Vet J
Safwat MS, Abdel-Haleem M, Refaei OH, M SE, Khalil GM, Ali ME, Mohamed ESA, Orabi A, Rayan AA, Karam R, Sargious MAN, Abdallah MI, Eid S, Osman MM, Elshawadfy AA, Anwer AZ.   +15 more
europepmc   +1 more source

The TUBA1B–G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin, Hechun Lin, Junming Yu, Chao Ge, Lin Mao, Saihua Zhang, Yizi Jin, Yunyu Wu, Taoyang Chen, Jinjun Li, Hong Li   +10 more
wiley   +1 more source

A comparative study of mNGS and tNGS for pathogen detection in paired upper and lower respiratory tract specimens from pediatric pneumonia patients. [PDF]

Microbiol Spectr
Zhao J, Zhang L, He W, Jian X, Han D, Shen A, Jiang L, Liu X.   +7 more
europepmc   +1 more source