Results 251 to 260 of about 89,623 (336)

Inflammation and epithelial–mesenchymal transition in a CFTR‐depleted human bronchial epithelial cell line revealed by proteomics and human organ‐on‐a‐chip

open access: yesThe FEBS Journal, EarlyView.
Proteomic analysis of cystic fibrosis transmembrane conductance regulator knockout (CFTR‐KO) clones of 16HBE14o‐ cells showed altered pathways linked to inflammation, polymorphonuclear leukocyte (neutrophil) recruitment, and epithelial–mesenchymal transition.
Domenico Mattoscio   +19 more
wiley   +1 more source

An adamantane‐based ligand as a novel chemical tool for thermosensory TRPM8 channel therapeutic modulation

open access: yesThe FEBS Journal, EarlyView.
Transient receptor potential cation channel subfamily M member 8 (TRPM8) is a cationic thermosensory channel crucial for cold sensation and menthol response. TRPM8 dysfunction leads to sensory symptoms such as cold allodynia. Targeting TRPM8 is important for treating diseases like peripheral neuropathies and cancer.
Angela Lamberti   +9 more
wiley   +1 more source

Prevalence and epidemiology of <i>Mycoplasma genitalium</i> and the absence of macrolide resistance in <i>M. genitalium</i> among pregnant women attending antenatal care in Zambia. [PDF]

open access: yesFront Public Health
Schröder D   +15 more
europepmc   +1 more source

Efficacy of Leucomycin on Mycoplasma pneumoniae Infections

open access: bronze, 1985
Yoshinao Takeuchi   +6 more
openalex   +2 more sources

The N6‐methyladenosine reader IGF2BP3 promotes bladder cancer progression through enhancing HSP90AB1 expression

open access: yesThe FEBS Journal, EarlyView.
N6‐methyladenosine (m6A) is a frequently occurring RNA modification that has emerged as an important player in tumour development through post‐transcriptional gene regulation. In this study, we found that IGF2BP3 modulates HSP90AB1 expression in an m6A modification‐dependent manner, activating the PI3K/AKT‐signaling pathway, and thereby promoting the ...
Xiaoqing Chen   +10 more
wiley   +1 more source

Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity

open access: yesThe FEBS Journal, EarlyView.
RANKL treatment induces expression of the aconitate decarboxylase (ACOD1) in differentiating osteoclasts, which increases succinate levels. The initially high expression of ACOD1 decreases towards the end of differentiation when the levels of the desuccinylase SIRT5 increase. Succinylation of citrate synthase (CS) was detected exclusively in stimulated
Dayoung Yu   +7 more
wiley   +1 more source

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