Results 81 to 90 of about 26,893 (258)

Remarkable remission of a tumor‐stage mycosis fungoides on the scalp by single fraction palliative radiotherapy

Clinical Case Reports, 2022
For tumor‐stage mycosis fungoides, systemic therapy in combination with skin‐directed local therapy is the mainstay of treatment. Here, we report a case where a tumor‐stage mycosis fungoides of the scalp showed a remarkable response to single fraction ...
Atsuto Katano
doaj   +1 more source

STAT5 induces miR-21 expression in cutaneous T cell lymphoma [PDF]

, 2016
In cutaneous T cell lymphomas (CTCL), miR-21 is aberrantly expressed in skin and peripheral blood and displays anti-apoptotic properties in malignant T cells. It is, however, unclear exactly which cells express miR-21 and what mechanisms regulate miR-21.
Blümel, Edda, Bonefeld, Charlotte M., Fredholm, Simon, Geisler, Carsten, Gluud, Maria, Hu, Tengpeng, Iversen, Lars, Joseph, Claudine, Jæhger, Ditte, Jønson, Lars, Koralov, Sergei B., Krejsgaard, Thorbjørn, Lindahl, Lise M., Litvinov, Ivan V., Mongan, Nigel P., Nastasi, Claudia, Nielsen, Boye Schnack, Odum, Niels, Persson, Jenny L., Petersen, David L., Ralfkiaer, Elisabeth, Sasseville, Denis, Sibbesen, Nina, Wasik, Mariusz A., Willerslev-Olsen, Andreas, Woetmann, Anders   +25 more
core   +2 more sources

The diagnosis of early‐stage mycosis fungoides: Views held by experts and non‐experts in cutaneous lymphoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Mycosis fungoides (MF) accounts for the majority of cutaneous lymphomas (CL). There is a documented delay in the diagnosis of early‐stage MF. However, its timely diagnosis is paramount to avoid potentially harmful therapies and undue patient distress.
Paula Beatty, Kevin Molloy, Stefanie Porkert, Megan Power Foley, Anne‐Marie Tobin, Franz Trautinger, Julia Scarisbrick, Constanze Jonak   +7 more
wiley   +1 more source

Increased Expression of Delta-like Ligand 4 in Mycosis Fungoides

Acta Dermato-Venereologica, 2020
In many malignancies, dysregulation of the Notch pathways, composed of 4 Notch receptors (Notch1–4) and 5 Notch ligands (Jagged1–2, Delta-like ligand-1, 3–4), is associated with their development.
Hikari Boki, Tomomitsu Miyagaki, Yuki Shono, Hiroaki Kamijo, Tomonori Oka, Hiraku Suga, Yoshihide Asano, Makoto Sugaya, Shinichi Sato   +8 more
doaj   +1 more source

Cirulating Sézary Cells in the Diagnosis of Sézary Syndrome (Quantitative and Morphometric Analyses) [PDF]

, 1983
Plastic-embedded circulating Sézary cells were examined in semithin and thin sections (assisted by the nuclear contour index-NCI). Eight cases of Sézary syndrome were analyzed as well as 11 controls (3 cases of widespread eczemas and 8 cases of ...
Braun-Falco, Otto, Burg, Guenter, Schmoeckel, Christian, Stolz, Wilhelm   +3 more
core   +1 more source

Oligonucleotide array-CGH identifies genomic subgroups and prognostic markers for tumor stage mycosis fungoides [PDF]

, 2018
Mycosis fungoide (MF) patients who develop tumors or extracutaneous involvement usually have a poor prognosis with no curative therapy available so far.
Barranco, Carlos, Cigudosa, Juan Cruz, Dummer, Reinhard, Espinet Solà, Blanca, Estrach Panella, Ma. Teresa (María Teresa), Ferreira, Bibiana I., Gallardo, Fernando, Garcia-Muret, Maria P., Herrera, Marta, Karpova, Maria B., Muniesa Montserrat, Cristina, Ortiz Romero, Pablo L., Pujol, Ramon M., Romagosa, Vicenç, Salgado, Rocío, Salido Galeote, Marta, Serrano, Sergi, Servitje Bedate, Octavio, Solé Ristol, Francesc, Suela, Javier, Sánchez Schmidt, Júlia, Tensen, Cornelis P., Vermeer, Maarten H., Zipser, Marie C.   +23 more
core   +1 more source

Lymphomatoid Papulosis Following Spesolimab Treatment for Generalised Pustular Psoriasis

Australasian Journal of Dermatology, EarlyView.
Mizuho Namba, Mika Matsumoto, Naoya Saito, Atsuko Kimura, Chihiro Sagara, Daiki Rokunohe, Eijiro Akasaka   +6 more
wiley   +1 more source

Successful Treatment of Erythrodermic Mycosis Fungoides with Mogamulizumab Followed by Etoposide Monotherapy

Case Reports in Oncology, 2018
Mogamulizumab induces cytotoxicity against CCR4+ lymphoma cells by antibody-dependent cell-mediated cytotoxicity in advanced cutaneous T-cell lymphoma patients. Since the efficacy of mogamulizumab in mycosis fungoides (28.6%) is lower than that in Sézary
Taku Fujimura, Kayo Tanita, Yota Sato, Yumi Kambayashi, Sadanori Furudate, Akira Tsukada, Akira Hashimoto, Setsuya Aiba   +7 more
doaj   +1 more source

Langerhans cell hyperplasia in the tumor stage of mycosis fungoides: a mimic of Langerhans cell histiocytosis [PDF]

, 2011
Mycosis fungoides is a form of cutaneous T-cell lymphoma (CTCL). Malignant CD4+ T cells have been found to adopt the T-regulatory (Treg) cell phenotype and function.
Lin, Tzu-Chun, Wu, Po-Yuan, Lin, Tze-Yi, Yeh, Su-Peng, Chen, Shyh-chang, Lee, Tsong-Liang   +5 more
core   +2 more sources

Effectiveness and safety of methotrexate in the treatment of mycosis fungoides: Real‐world data from a multicentre study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Methotrexate (MTX) has been a longstanding therapeutic option for mycosis fungoides (MF); however, data on its real‐world effectiveness remain limited. This study aimed to assess real‐world outcomes of oral MTX in the treatment of MF. Data from five referral centres for cutaneous lymphoma in Greece were retrospectively reviewed with the baseline‐ and ...
Vasiliki Nikolaou, Evdoxia Panou, Antonios Tsimpidakis, Ioannis‐Alexios Koumprentziotis, Aikaterini Patsatsi, Marina Siakantaris, Sabine‐Elke Kruger‐Krasagakis, Leonidas Marinos, Elisavet Georgiou, Kyriaki Lampadaki, Aliki Velissari, Athina‐Ioanna Daponte, Aikaterini Doxastaki, Stella Kaliampou, Aristeidis Vaiopoulos, Iliana Konstandinou, Marios Koumourtzis, Eleftheria Lakiotaki, Vassiliki Pappa, Athanasios Tsamaldoupis, Alexander Stratigos, Evangelia Papadavid   +21 more
wiley   +1 more source