Results 81 to 90 of about 27,061 (270)

New Topical and Systemic Treatments for Atopic Dermatitis

Clinical &Experimental Allergy, EarlyView.
This review summarises new topical and systemic treatments for atopic dermatitis, their relative effectiveness, and important safety data. ABSTRACT Atopic dermatitis is an inflammatory skin condition characterised by pruritus and a chronic relapsing–remitting course.
Sara Mirali, Aaron M. Drucker
wiley   +1 more source

Mycosis Fungoides and Associated Malignancies in a Dutch Nationwide Retrospective Cohort Study

Acta Dermato-Venereologica
The prognosis of patients with mycosis fungoides is variable. As the current literature is scarce and shows mixed results this study investigates the incidence of other primary malignancies in mycosis fungoides patients.
Rosanne Ottevanger, Esther Vermaas, Rein Willemze, Anne-Roos Schrader, Patty M. Jansen, Jelle J. Goeman, Hein Putter, Maarten H. Vermeer, Koen D. Quint   +8 more
doaj   +1 more source

Increased Expression of Delta-like Ligand 4 in Mycosis Fungoides

Acta Dermato-Venereologica, 2020
In many malignancies, dysregulation of the Notch pathways, composed of 4 Notch receptors (Notch1–4) and 5 Notch ligands (Jagged1–2, Delta-like ligand-1, 3–4), is associated with their development.
Hikari Boki, Tomomitsu Miyagaki, Yuki Shono, Hiroaki Kamijo, Tomonori Oka, Hiraku Suga, Yoshihide Asano, Makoto Sugaya, Shinichi Sato   +8 more
doaj   +1 more source

STAT5 induces miR-21 expression in cutaneous T cell lymphoma [PDF]

, 2016
In cutaneous T cell lymphomas (CTCL), miR-21 is aberrantly expressed in skin and peripheral blood and displays anti-apoptotic properties in malignant T cells. It is, however, unclear exactly which cells express miR-21 and what mechanisms regulate miR-21.
Blümel, Edda, Bonefeld, Charlotte M., Fredholm, Simon, Geisler, Carsten, Gluud, Maria, Hu, Tengpeng, Iversen, Lars, Joseph, Claudine, Jæhger, Ditte, Jønson, Lars, Koralov, Sergei B., Krejsgaard, Thorbjørn, Lindahl, Lise M., Litvinov, Ivan V., Mongan, Nigel P., Nastasi, Claudia, Nielsen, Boye Schnack, Odum, Niels, Persson, Jenny L., Petersen, David L., Ralfkiaer, Elisabeth, Sasseville, Denis, Sibbesen, Nina, Wasik, Mariusz A., Willerslev-Olsen, Andreas, Woetmann, Anders   +25 more
core   +2 more sources

Brentuximab vedotin as monotherapy or combination therapy for cutaneous peripheral T cell lymphoma – a retrospective study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Cutaneous peripheral T cell lymphomas (PTCL) are rare and show an aggressive course with limited response to therapy. The efficacy of brentuximab vedotin in cutaneous peripheral T cell lymphomas has not yet been systematically investigated.
Caroline Glatzel, Inga Hansen‐Abeck, Nina Booken, Johannes Düll, Matthias Goebeler, Patrick Schummer, Marion Wobser   +6 more
wiley   +1 more source

Low‐dose total skin electron beam therapy in erythrodermic mycosis fungoides and Sézary syndrome: Results From the Prospective S‐MISR Study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Erythrodermic mycosis fungoides (eMF) and Sézary syndrome (SS) often show delayed and non‐durable clinical responses to systemic therapies. Patients and Methods A total of 35 patients with eMF or SS were treated with total skin electron beam therapy (TSEBT).
Khaled Elsayad, Christian Kandler, Jan Jakob Siats, Niklas Pepper, Moritz Fabian Danzer, Gabor Dobos, Elisabeth Livingstone, Susanne Melchers, Johannes Kleemann, Julia Hyun, Claudia Pföhler, Peter von den Driesch, Jan P. Nicolay, Rudolf Stadler, Hans Theodor Eich   +14 more
wiley   +1 more source

High Expression of Fas/CD95 on CD4+ Circulating T Cells: An Exclusion Criterion in the Diagnosis of Mycosis Fungoides?

Acta Dermato-Venereologica, 2017
The aim of this 10-year monocentric prospective study was to determine a cut-off value of Fas/CD95 expression by peripheral blood CD4+ T lymphocytes in discriminating patients with mycosis fungoides from controls with cutaneous benign lymphocytic ...
Aurélie Du-Thanh, Pierre Portalès, Anne Serre-Cousiné, Céline Girard, Bernard Guillot, Olivier Dereure   +5 more
doaj   +1 more source

Molecular cytogenetic characterization of breakpoints in 19 patients with hematologic malignancies and 12p unbalanced translocations [PDF]

, 2003
Structural rearrangements of the short arm of chromosome 12 are frequent cytogenetic findings in various hematologic malignancies. The ETV6 gene is the most common target for rearrangements in 12p13.
Calasanz-Abinzano, M.J. (Maria Jose), Carlson, K. (K.), Lahortiga, I. (Idoya), Odero, M.D. (Maria Dolores), Rowley, J.D. (Janet D.)   +4 more
core   +1 more source

Brentuximab vedotin and radiotherapy for CD30‐positive cutaneous T‐cell lymphoma – a retrospective multicenter analysis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives While brentuximab vedotin (BV) and radiotherapy (RTx) are established treatment options for CD30‐positive cutaneous T‐cell lymphoma (CTCL), data on their simultaneous or sequential use regarding efficacy and tolerability remain scarce.
Patrick Schummer, Caroline Glatzel, Philipp Schrüfer, Ingulf Lawrenz, Gabor Dobos, Ulrike Wehkamp, Svea Hüning, René Stranzenbach, Jan P. Nicolay, Matthias Goebeler, Marion Wobser   +10 more
wiley   +1 more source

Langerhans cell hyperplasia in the tumor stage of mycosis fungoides: a mimic of Langerhans cell histiocytosis [PDF]

, 2011
Mycosis fungoides is a form of cutaneous T-cell lymphoma (CTCL). Malignant CD4+ T cells have been found to adopt the T-regulatory (Treg) cell phenotype and function.
Lin, Tzu-Chun, Wu, Po-Yuan, Lin, Tze-Yi, Yeh, Su-Peng, Chen, Shyh-chang, Lee, Tsong-Liang   +5 more
core   +2 more sources