Results 121 to 130 of about 184,937 (258)

Myelin-Oligodendrocyte Glycoprotein Antibodies Spectrum Disorders

Caspian Journal of Neurological Sciences, 2017
Myelin-Oligodendrocyte Glycoprotein (MOG) is an adhesive molecule responsible for myelin sheath structural integrity and maintenance. Patients with spectrum of inflammatory demyelinating disease particularly in central nervous system are reported to have
Masoud Etemadifar, Ali Fazli
doaj  

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Clinical Features and Risk of Relapse in Children and Adults with Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease

Annals of Neurology, 2020
The main objective was to compare clinical features, disease course, and myelin oligodendrocyte glycoprotein (MOG) antibody (Ab) dynamics between children and adults with MOG‐Ab–associated disease (MOGAD).
Á. Cobo-Calvo, A. Ruiz, F. Rollot, G. Arrambide, R. Deschamps, E. Maillart, C. Papeix, B. Audoin, A. Lepine, H. Maurey, H. Zéphir, D. Biotti, J. Ciron, F. Durand-Dubief, N. Collongues, X. Ayrignac, P. Labauge, P. Meyer, E. Thouvenot, B. Bourre, A. Montcuquet, M. Cohen, Philippe Horello, M. Tintoré, J. de Sèze, S. Vukusic, K. Deiva, R. Marignier   +27 more
semanticscholar   +1 more source

IgG Subclass (IgG1‐4) and IgA Autoantibody Profiles Against Muscle‐Specific Kinase in a Greek Cohort

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Muscle‐specific kinase myasthenia gravis (MuSK‐MG) is an autoimmune neuromuscular disorder predominantly mediated by IgG4 autoantibodies disrupting MuSK signaling. The contribution of other isotypes remains incompletely defined. We characterized the serological profile of a Greek cohort of MuSK‐MG patients.
Sofia‐Natsοuko Gkotzamani, Maria Pechlivanidou, Francisca Faber, Cansu Elmas, Vasiliki Zouvelou, Elisabeth Chroni, Dimitrios Tzanetakos, Maria Kourouvani, Marlene Wolfsgruber, Ioannis Zaganas, Dimitra Kolovou, Michael Rentzos, Ariadne Daponte, Maria Chondrogiorgi, Spyridon Konitsiotis, Georgios Nicolaou, Stavroula Salakou, Sotirios Giannopoulos, Konstandinos Lazaridis, Georgios Tsivgoulis, Socrates Tzartos, Inga Koneczny, John S. Tzartos   +22 more
wiley   +1 more source

Myelin oligodendrocyte glycoprotein antibody-associated disease mimicking CLIPPERS syndrome: case report and literature review

Heliyon
Introduction: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a central nervous system's autoimmune disorder caused by antibodies targeting the oligodendrocyte glycoprotein.
Julio César Mantilla - Pardo, Jose Ricardo Muñoz - Zuñiga, Juan David Tascón - Romero, Jairo Alonso Quiñones - Bautista   +3 more
doaj   +1 more source

Early Remission of Cerebrospinal Fluid Interleukin‐6 After Initial Immunotherapy Predicts a Good Prognosis in Autoimmune Encephalitis

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Autoimmune encephalitis therapy requires adjusting the regimen based on therapeutic response; however, clinical indicators of this response remain unknown. Aim To determine the predictive capability of cerebrospinal fluid (CSF), electroencephalography (EEG), and brain magnetic resonance imaging (MRI) in identifying responders to ...
Yuta Madokoro, Yuto Uchida, Hiroyasu Inoue, Toyohiro Sato, Teppei Fujioka, Masayuki Mizuno, Shoji Kawashima, Masahiro Oomura, Noriyuki Matsukawa   +8 more
wiley   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

Brain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu, Yoshiki Takai, Naoya Yamazaki, Sarah Brandl, Katharina M. Mair, Thibault Bouderlique, Maria Eleni Kastriti, Igor Adameyko, Romana Höftberger, Markus Reindl, Jan Bauer, Monika Bradl   +11 more
wiley   +1 more source

The relationship between serum MOG-IgG titer status and titers and the prognosis of pediatric MOGAD: a retrospective cohort study

Frontiers in Pediatrics
BackgroundTo explore the clinical value of MOG-IgG serum titer change and duration in predicting the relapse of MOGAD in children.MethodsThe clinical data, imaging data and laboratory examination results of 63 children with MOGAD were analyzed, and the ...
Mengfan Pei, Yuyang He, Shan Huang, Cong Yao, Jing Chen, Lanhong Xiang, Chunhui Yuan, Hongmin Zhu   +7 more
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Is there an immunological cross-reactivity of antibodies to the myelin oligodendrocyte glycoprotein and coronaviruses? [PDF]

Recent reports indicated that myelin oligodendrocyte glycoprotein antibody-associated disease might be a rare complication after severe acute respiratory syndrome coronavirus 2 infection or vaccination.
Boso, Federica, Rudzki, Dagmar, Rossi, Patrizia, Rostasy, Kevin, Bauer, Angelika, Mariotto, Sara, Wendel, Eva-Maria, Wildemann, Brigitte, Kümpfel, Tania, Reindl, Markus, Schanda, Kathrin, Jarius, Sven, Engels, Daniel, Dinoto, Alessandro, Giometto, Bruno, Ferrari, Sergio   +15 more
core   +1 more source