Results 141 to 150 of about 184,937 (258)

ICU Management of COVID-19 vaccine-related myelin oligodendrocyte glycoprotein IgG-association encephalomyelitis

, 2022
This is a 19 y.o. woman with a history of bipolar disorder admitted to the hospital for Myelin Oligodendrocyte Glycoprotein IgG-Associated Encephalomyelitis. She received her COVID-19 vaccination 5 days prior to symptom onset.
Vrtar, Andrew, Haddad, Moshe, Soto, Roy G   +2 more
core   +1 more source

Antibodies to Oligodendrocyte Glycoprotein in Children with ADEM

Pediatric Neurology Briefs, 2010
Antibodies to native myelin oligodendrocyte glycoprotein (nMOG) in 47 children during a first episode of CNS demyelination (acute disseminated encephalomyelitis [ADEM] in 19, and a clinical isolated syndrome [CIS] in 28) were investigated by a cell-based
J Gordon Millichap
doaj   +1 more source

Prolonged Headache in a 13‐Year‐Old Girl With Acute Lymphoblastic Leukemia: A Case of Possible Neuroinflammatory Complication Responsive to Intravenous Immunoglobulin

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Neurological complications in pediatric acute lymphoblastic leukemia (ALL) may result from disease, CNS involvement, or treatment. We report a 13‐year‐old girl with persistent headache and blurred vision suggestive of raised intracranial pressure.
Amereh Hadizadeh, Hossein Esfahani, Firozeh Hosseini, Afshin Fayyazi, Nasibeh Ghalandari   +4 more
wiley   +1 more source

Oligodendrocyte-myelin glycoprotein (OMgp) is an inhibitor of neurite outgrowth [PDF]

, 2002
A protein fraction purified from bovine brain myelin, previously called arretin because of its ability to inhibit neurite outgrowth, has been identified as consisting predominantly of oligodendrocyte-myelin glycoprotein (OMgp).
Gurenko, AA, Kuzmin, D. V., Yaxley, GM, Yaxley, G. M., Sobolev, Alexander V.; Hofmann, Albrecht W.; Kuzmin, Dmitry V.; Yaxley, Gregory M.; Arndt, Nicholas T.; Chung, Sun-Lin; Danyushevsky, Leonid V.; Elliott, Tim; Frey, Frederick A.; Garcia, Michael O.; Gurenko, Andrey A.; Kamenetsky, Vadim S.; Kerr, Andrew C.; Krivolutskaya, Nadezhda A.; Matvienkov, Vladimir V.; Nikogosian, Igor K.; Rocholl, Alexander; Sigurdsson, Ingvar A.; Sushchevskaya, Nadezhda M.; Teklay, Mengist, Zhang, Rulin, Kottis, V., Sobolev, A. V., Oldham, S, Danyushevsky, L. V., Hemmings, B A, Lourderaj, Upakarasamy, Sushchevskaya, NM, Hoffman, AW, Pierre Thibault, Krivolutskaya, NA, Matvienkov, VV, Frey, F. A., Sobolev, A.V., Kerr, A. C., Rocholl, A., Braun, P.E., Arndt, N.T., Hofmann, A. W., Wester, Roland, Sigurdsson, IA, Xiao, Z.-C., TUCCIMEI, Paola, Kuzmin, DV, Xiao, Zhi-Cheng, Kerr, AC, Zhang, R., Thibault, P., Arndt, N. T., Kuzmin, D.V., Laffargue, M, Elliott, T., Pauline Dergham, Matvienkov, V. V., Hofmann, A.W., Kamenetsky, VS, Dergham, P., Thibault, Pierre, Mikol, Daniel D., FORNÓS J, Chung, S.L., Stocker, H, Sushchevskaya, N. M., Elliott, TR, Nikogosian, I., Yaxley, G.M., Garcia, M.O., Rocholl, A, Mikosch, Jochen, Gurenko, A. A., Sigurdsson, I. A., PEATE D. W., Garcia, MO, Sun, Rui, Chung, S-L, Garcia, M. O., Wymann, M P, Mikol, D., Matvienkov, V.V., Elliott, T.R., Zhang, Jiaxu, Danyushevsky, L.V., Kamenetsky, V.S., Sobolev, AV, ONAC B. P, Krivolutskaya, N. A., Rulin Zhang, Teklay, M., Sigurdsson, I.A., Nikogosian, I.; id_orcid, Chung, S. L., Danyushevsky, LV, Vicky Kottis, Daniel Mikol, Gurenko, A.A., Kottis, Vicky, Peter E. Braun, Hafen, E, DORALE J, Sushchevskaya, N.M., Krivolutskaya, N.A., Frey, FA, Kamenetsky, V. S., Hase, William L., Nikogosian, I. K., Frey, F.A., Arndt, NT, Andjelkovic, M, GINÉS J, Dergham, Pauline, Teklay, M, Nikogosian, IK, GINÉS A, Zhi‐Cheng Xiao, Kerr, Andrew Craig, Braun, Peter E.   +100 more
core   +1 more source

Recent Advancements in Drug Delivery Across the Blood–Brain Barrier in Amyotrophic Lateral Sclerosis (ALS)

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Progressive BBB/BSCB dysfunction is increasingly recognized as both a pathological feature and a therapeutic barrier in ALS. Novel delivery technologies and barrier‐restoration strategies may enhance CNS drug exposure, improve the efficacy of disease‐modifying therapies, and advance ALS treatment. ABSTRACT Background Amyotrophic lateral sclerosis (ALS)
Nitesh Sanghai, Kaitlyn Pierce, Nidhi Sharma, Sasha Leggett, Tara Chand Yadav, Pegah Masrori, Devi Atukorallaya, Senthilnathan Palaniyandi, Paul C. Marcogliese, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Asymptomatic Optic Nerve Enhancement in Myelin Oligodendrocyte Glycoprotein Associated Disease

, 2022
The rate of asymptomatic optic nerve enhancement on magnetic resonance imaging (MRI) has been reported as high as 51% in neuromyelitis optica (1), but has not been explored in patients with myelin oligodendrocyte glycoprotein antibody associated disease (
Mary Labowsky; Sanders Chang; Himanshu Sharma; Puneet Belani; Michael Schecht; Bradley Delman; Mark Kupersmith
core  

Translational insights from EAE models : decoding MOGAD pathogenesis and therapeutic innovation

Frontiers in Immunology
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD) is a rare acquired demyelinating syndrome manifesting as optic neuritis (ON), transverse myelitis (TM), acute disseminated encephalomyelitis (ADEM), and brainstem encephalitis.
Yanjia Zhang, Yanjia Zhang, Dong Li, Dong Li   +3 more
doaj   +1 more source

Emodin Suppresses the RAGE/ROCK1 Pathway to Modulate the Oligodendrocyte Lineage and Ameliorate Demyelination in Vascular Dementia Rats

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Emodin improves white matter remyelination and alleviates cognitive deficits through suppression of the RAGE/ROCK1 signaling pathway in VD rats. Mechanistically, it modulates the OL lineage by reducing the elevated proliferative response of OPCs while promoting their maturation and remyelination.
Xueqing Wang, Xiumei Dong, Cunbao He, Junjie Zhang, Wenming Ban, Guoqi Zhu, Jingji Wang, Yilan Zhen   +7 more
wiley   +1 more source

Myelin Oligodendrocyte Glycoprotein (MOG) - Antibody Optic Neuritis

, 2020
This is an illustrated guide to the clinical diagnosis of myelin oligodendrocyte glycoprotein (MOG)-antibody optic neuritis. Myelin oligodendrocyte glycoprotein (MOG) is a glycoprotein on the surface of myelin and is found exclusively in the central ...
Bryce Buchowicz, MD; Valérie Biousse, MD
core  

Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitors

Life Science Alliance
Inhibitory anti-ADAM17 monoclonal antibodies (mAbs) abrogate the cleavage of p75 in a neuroblastoma-glioma cell line. Upon spinal cord injury, axons attempting to regenerate need to overcome the repulsive actions of myelin-associated inhibitors ...
Nayanendu Saha, Eric Chan, Rachelle P Mendoza, Yevgeniy Romin, Murray J Tipping, Dimitar B Nikolov   +5 more
doaj   +1 more source