Results 151 to 160 of about 5,959 (257)

Transcranial Pulse Stimulation Enhances Dexterity in Parkinson's Disease: A Randomized Sham‐Controlled Trial

Movement Disorders, EarlyView.
Abstract Background Ultrasound‐based neuromodulation, capable of reaching deep brain areas with high precision, represents cutting‐edge technology in non‐invasive brain stimulation and is investigated as a novel treatment for neurological and psychiatric disorders, including Parkinson's disease (PD).
Eva Matt, Nina Plischek, Michael Mitterwallner, Sonja Radjenovic, Alexandra Weber, Alina Domitner, Gregor Dörl, Anna Zettl, Sarah Osou, Anna Leitgeb, Agnes Santer, Viktoria Winkler, Julia Mandelburger, Heidemarie Zach, Roland Beisteiner   +14 more
wiley   +1 more source

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Administration of Schwann Cell‐Like Cells Differentiated From Tonsil‐Derived Mesenchymal Stem Cells Promotes Peripheral Nerve Regeneration by Inducing Macrophage Polarization in a Chronic Constriction Injury Model

Muscle &Nerve, EarlyView.
TMSC‐SCs were mixed with fibrin adhesive and administered into the sciatic nerve of CCI rats, and nerve conduction studies and histopathological observations confirmed the regeneration of the peripheral nerve and gastrocnemius muscle. In addition, the expression of M1 and M2 macrophage markers was observed after the administration of TMSC‐SCs. ABSTRACT
Yu Hwa Nam, Ji‐Sup Kim, Yoonji Yum, Juhee Yoon, Youbeen Cho, Jaeseung Lim, Saeyoung Park, Sung‐Chul Jung   +7 more
wiley   +1 more source

Curcumin Alleviates the Osteogenesis Inhibition and the Aging Process in BMSCs Induced by Iron Overload Through Activating the NRF2/GPX4 Pathway

Phytotherapy Research, EarlyView.
Under iron overload conditions, curcumin inhibits cellular senescence and promotes osteogenic differentiation by activating the NRF2/GPX4 signaling pathway in bone marrow mesenchymal stem cells (BMSCs), thereby preventing the onset of osteoporosis. ABSTRACT Dysregulated proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs ...
Jingmin Che, Qing Feng, Zhixia Zhao, Jingying Sun, Weihao Ren, Yangmeng Feng, Cuixiang Xu, Xu‐Hui Li   +7 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Compactification of a myelin mimetic Langmuir monolayer upon adsorption and unfolding of myelin basic protein

, 2005
The surface shear viscosity of a myelin mimetic Langmuir monolayer is investigated upon adsorption of myelin basic protein (MBP). We measure an increase of the surface shear viscosity at picomolar concentrations of the protein, suggesting that the ...
Fischer, Anna, Wen, H. Z., Ruschel, Y., Fischer, T. M., Khattari, Z.   +4 more
core  

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Dopamine: The Essential Bridge Mediating Obstructive Sleep Apnea and Hippocampus‐Dependent Learning and Memory Impairments

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea is a clinical syndrome that triggers a series of pathophysiologic changes, including disturbed sleep architecture, chronic intermittent hypoxia and hypercapnia, and ultimately severe cognitive dysfunction. The hippocampus plays a key role in various cognitive processes such as learning and memory.
Rui Fan, Tao Li, Yan Yan
wiley   +1 more source

Extraocular Photoreception in Optic Lobes, Suckers, and Skin of Octopus vulgaris

Integrative Zoology, EarlyView.
Evidence of extra‐ocular photoreception in Octopus vulgaris (a) Diagram of the O. vulgaris different tissues considered: SPB, sucker proximal big; SPL, sucker proximal large; SM, sucker medium; SD, sucker distal; SK, skin; OL, optic lobes; RT, retina; (b‐d) Gene expression analysis of Ov‐GRK1 (red), Ov‐retinochrome (green), Ov‐rhodopsin (blue) mRNA ...
Valeria Maselli, Al‐Sayed Al‐Soudy, Mariangela Norcia, Stefania Galdiero, Sara Palladino, Emanuela Cirillo, Gianluca Polese, Anna Di Cosmo   +7 more
wiley   +1 more source