Results 211 to 220 of about 48,603 (346)

Genetic Inactivation of the Serotonin Transporter Dysregulates Expression of Neurotransmission Genes and Genome‐Wide DNA Methylation Levels in the Medial Prefrontal Cortex of Male Rats During Postnatal Development

Developmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Reduced expression of the serotonin transporter (5‐hydroxytryptamine transporter, 5‐HTT) in early life has been associated with a delay in postnatal brain development and endophenotypes of a variety of neuropsychiatric and neurodevelopmental disorders in adolescence and adulthood.
Yvet Kroeze, Martin Oti, Roel H. M. Cooijmans, Ellen van Beusekom, Leonie I. Kroeze, Anthonieke Middelman, Hans van Bokhoven, Sharon M. Kolk, Judith R. Homberg, Huiqing Zhou   +9 more
wiley   +1 more source

Cholinergic and Glutamatergic Axons Differentially Require Glial Support in the Drosophila PNS

Glia, Volume 73, Issue 7, Page 1365-1382, July 2025.
Main Points In the Drosophila PNS, motor‐ and sensory axons differentially interact with wrapping glia processes. Sensory axons are more weakly associated with wrapping glia and show a length dependent degeneration upon loss of wrapping glia. ABSTRACT In vertebrates, there is a differential interaction between peripheral axons and their associated ...
Steffen Kautzmann, Simone Rey, Amber Krebs, Christian Klämbt   +3 more
wiley   +1 more source

Disruption of Oligodendroglial Autophagy Leads to Myelin Morphological Deficits, Neuronal Apoptosis, and Cognitive Decline in Aged Mice

Glia, Volume 73, Issue 7, Page 1383-1397, July 2025.
Main Points Ablation of autophagy in oligodendrocytes reveals increased PLP expression, myelin abnormalities, axon degeneration and increased microglia activation in aged mice. The aged mice exhibit marked deficits in learning and memory tasks. ABSTRACT The aging central nervous system (CNS) is often marked by myelin degeneration, yet the underlying ...
Niki Ktena, Dimitrios Spyridakos, Alexandros Georgilis, Ilias Kalafatakis, Efstathia Thomoglou, Angeliki Kolaxi, Vassiliki Nikoletopoulou, Maria Savvaki, Domna Karagogeos   +8 more
wiley   +1 more source

Protective effect of miconazole on rat myelin sheaths following premature infant cerebral white matter injury

, 2018
Xuewen Su, Wenyan Tang, Zuo Luan, Yinxiang Yang, Zhaoyan Wang, Yu Zhang, Qian Wang, Lei Suo, Zhen Huang, Xiue Wang, Haifeng Yuan   +10 more
openalex   +2 more sources

Amyloid‐β Dysregulates Oligodendroglial Lineage Cell Dynamics and Myelination via PKC in the Zebrafish Spinal Cord

Glia, Volume 73, Issue 7, Page 1437-1451, July 2025.
Main Points Amyloid β peptide induces early oligodendrocyte differentiation and dorsal myelination in the zebrafish larvae spinal cord. Pan‐PKC inhibitor Gö6983 restores the aforementioned alterations in oligodendrocytes and myelin. ABSTRACT Soluble forms of amyloid‐β (Aβ) peptide have been proposed as candidates to induce oligodendrocyte (OL) and ...
Uxue Balantzategi, Adhara Gaminde‐Blasco, Christina A. Kearns, Laura Bayón‐Cordero, María Victoria Sánchez‐Gómez, José Luis Zugaza, Bruce Appel, Elena Alberdi   +7 more
wiley   +1 more source

Acid-sensing ion channel-1 contributes to the failure of myelin sheath regeneration following spinal cord injury by transcellular delivery of PGE2. [PDF]

Cell Mol Biol Lett
Wu Z, Han T, Dong Y, Ying W, Fang H, Liu Y, Song P, Shen C.   +7 more
europepmc   +1 more source

The X‐Linked Intellectual Disability Gene, ZDHHC9 , Is Important for Oligodendrocyte Subtype Determination and Myelination

Glia, Volume 73, Issue 7, Page 1452-1466, July 2025.
Main Points Zdhhc9 ablation grossly changes gene expression and myelin protein levels in CNS WM. Zdhhc9 is important for the establishment of mature oligodendrocyte subtypes. Zdhhc9 is important for axon myelination and the maintenance of myelin integrity.
Rocio B. White, Angela R. Wild, Timothy P. O'Leary, Andrew J. Thompson, Stephane Flibotte, Angie Peng, Jason C. Rogalski, Mila Mair, Neeki Derhami, Shernaz X. Bamji   +9 more
wiley   +1 more source

Myelin basic protein mRNA levels affect myelin sheath dimensions, architecture, plasticity, and density of resident glial cells. [PDF]

Glia
Bagheri H, Friedman H, Hadwen A, Jarweh C, Cooper E, Oprea L, Guerrier C, Khadra A, Collin A, Cohen-Adad J, Young A, Victoriano GM, Swire M, Jarjour A, Bechler ME, Pryce RS, Chaurand P, Cougnaud L, Vuckovic D, Wilion E, Greene O, Nishiyama A, Benmamar-Badel A, Owens T, Grouza V, Tuznik M, Liu H, Rudko DA, Zhang J, Siminovitch KA, Peterson AC.   +30 more
europepmc   +1 more source

Interpretation of inhomogeneous magnetization transfer in myelin water using a four‐pool model with dipolar reservoirs

Magnetic Resonance in Medicine, Volume 94, Issue 1, Page 278-292, July 2025.
Abstract Purpose To confirm ihMT's specificity to myelin, an ihMT presaturation module was combined with a Poon–Henkelman multi‐echo spin‐echo readout to separate the ihMT signal in myelin water from intra‐/extra‐cellular water. This study explored the relationship between two quantitative myelin imaging techniques and measured the ihMT signal of ...
Michelle H. Lam, Masha Novoselova, Andrew Yung, Valentin H. Prevost, Alan P. Manning, Jie Liu, Wolfram Tetzlaff, Piotr Kozlowski   +7 more
wiley   +1 more source

The RNA binding protein fragile X mental retardation protein promotes myelin sheath growth. [PDF]

Glia, 2020
Doll CA, Yergert KM, Appel BH.
europepmc   +1 more source