Results 211 to 220 of about 201,896 (346)
Main Points Loss of FMRP impairs human and rat oligodendrocyte (OL) morphology in vitro. FMRP‐deficient OLs show impaired maturation when engrafted in hypomyelinated mice. Rat Fmr1 knockout OLs show a delay in myelin sheath formation in vivo. ABSTRACT The Fragile X Messenger Ribonucleoprotein (FMRP) is an RNA binding protein that regulates the ...
Vidya Ramesh+15 more
wiley +1 more source
Effects of acrylamide exposure during pregnancy and lactation on the development of myelin sheath of corpus callosum in offspring rats. [PDF]
Liu S+9 more
europepmc +1 more source
Unexpected Remyelination in the Absence of Matrix Metalloproteinase 7
Main Points MMP7 is not essential for demyelination and remyelination in the cuprizone model. MMP7‐/‐ mice fibronectin aggregates do not accumulate in the remyelination phase. MMP7‐/‐ mice have lower levels of fibronectin and hyaluronan after chronic demyelination.
Rianne P. Gorter+7 more
wiley +1 more source
Comparison of Weigert Stained Sections with Unfixed, Unstained Sections for Study of Myelin Sheaths [PDF]
Curt P. Richter, Carolyn L. Warner
openalex +1 more source
Main Points Inactivating the INO80 chromatin remodelling complex greatly extends the oligodendrocyte precursor (OP) cell cycle by prolonging G1. INO80 acts in OPs via histone H2A/H2A.Z exchange. INO80 binds the transcriptional regulator OLIG2 in OPs.
Jordan L. Wright+4 more
wiley +1 more source
Oligodendrocyte development and myelin sheath formation are regulated by the antagonistic interaction between the Rag-Ragulator complex and TFEB. [PDF]
Bouchard EL, Meireles AM, Talbot WS.
europepmc +1 more source
Abstract Small‐animal diffusion MRI (dMRI) has been used for methodological development and validation, characterizing the biological basis of diffusion phenomena, and comparative anatomy. The steps from animal setup and monitoring, to acquisition, analysis, and interpretation are complex, with many decisions that may ultimately affect what questions ...
Ileana O. Jelescu+56 more
wiley +1 more source
Density of sodium channels in mammalian myelinated nerve fibers and nature of the axonal membrane under the myelin sheath. [PDF]
J. M. Ritchie, R. B. Rogart
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Abstract The value of preclinical diffusion MRI (dMRI) is substantial. While dMRI enables in vivo non‐invasive characterization of tissue, ex vivo dMRI is increasingly being used to probe tissue microstructure and brain connectivity. Ex vivo dMRI has several experimental advantages including higher SNR and spatial resolution compared to in vivo studies,
Kurt G. Schilling+57 more
wiley +1 more source
Direct contacts of microglia on myelin sheath and Ranvier's node in the corpus callosum in rats. [PDF]
Zhang J, Yang X, Zhou Y, Fox H, Xiong H.
europepmc +1 more source