Main Points Brain oligodendrocytes have lower rates of cholesterol synthesis and higher rates of lipoprotein uptake than spinal cord oligodendrocytes. Myelin lipid content is higher in CNS regions with larger average axon diameter. Brain and spinal cord myelin cholesterol content is innately different, while myelin fatty acid content can be modulated ...
Marie L. Mather+4 more
wiley +1 more source
Effects of acrylamide exposure during pregnancy and lactation on the development of myelin sheath of corpus callosum in offspring rats. [PDF]
Liu S+9 more
europepmc +1 more source
What Does Iron Mean to an Oligodendrocyte?
Main Points Iron is essential for oligodendrocyte (OL) biology and myelin production, with deficiencies leading to severe neurological impairments. Understanding iron trafficking in OLs is crucial for developing treatments for dysmyelinating conditions. ABSTRACT Iron is essential for life and plays a key role in multiple fundamental cellular functions.
Quinn W. Wade, James R. Connor
wiley +1 more source
Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination [PDF]
et al.,, Mogha, Amit, Monk, Kelly
core +1 more source
This study explores the role of Central Pattern Generators (CPGs) in locomotor recovery after spinal cord injury (SCI). It examines CPG organization, function, and modulation through amino acids, biogenic amines, and acetylcholine. Therapeutic strategies, including pharmacological, electrical, and optogenetic approaches, are reviewed, alongside current
Hao Su+4 more
wiley +1 more source
Oligodendrocyte development and myelin sheath formation are regulated by the antagonistic interaction between the Rag-Ragulator complex and TFEB. [PDF]
Bouchard EL, Meireles AM, Talbot WS.
europepmc +1 more source
Comparison of Weigert Stained Sections with Unfixed, Unstained Sections for Study of Myelin Sheaths [PDF]
Curt P. Richter, Carolyn L. Warner
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A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia+4 more
wiley +1 more source
Myelin sheath structure and regeneration in peripheral nerve injury repair. [PDF]
Liu B+15 more
europepmc +1 more source
Density of sodium channels in mammalian myelinated nerve fibers and nature of the axonal membrane under the myelin sheath. [PDF]
J. M. Ritchie, R. B. Rogart
openalex +1 more source