P4–287: Effect of GETO extract on myelin sheath structure and myelin basic protein content in the brain with AD model [PDF]
Jinzhou Tian+5 more
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ABSTRACT Aim Leucine‐rich repeat transmembrane proteins (LRRTMs) are synaptic adhesion proteins that regulate synapse development and function. They interact transsynaptically with presynaptic binding partners to promote presynaptic differentiation. Polymorphisms of LRRTM4, one of the four members of this protein family, have been linked to multiple ...
Eva Tatzl+7 more
wiley +1 more source
Myosin II has distinct functions in PNS and CNS myelin sheath formation [PDF]
Haibo Wang+4 more
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The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease
ABSTRACT Cerebral small vessel disease (cSVD) is a significant global health issue, accounting for approximately 25% of ischemic strokes and 20% of all dementia cases. CADASIL, the most common monogenic form of cSVD, is caused by stereotyped mutations in the NOTCH3 receptor that alter the number of cysteine residues in its extracellular domain ...
Anne Joutel
wiley +1 more source
Absence of 2-Hydroxylated Sphingolipids Is Compatible with Normal Neural Development But Causes Late-Onset Axon and Myelin Sheath Degeneration [PDF]
Inge Zöller+6 more
openalex +1 more source
In progressive MS, mixed active plaques and perivascular inflammation in the sub/juxtacortical white matter correlate with similar (albeit fainter) pathologies in the cortical parenchyma Abstract It remains elusive whether lesions and inflammation in the sub/juxtacortical white matter reflect cortical and/or meningeal pathologies.
Betül Okutan+10 more
wiley +1 more source
Effects of Alpha Lipoic Acid on Loss of Myelin Sheath of Sciatic Nerve in Experimentally Induced Diabetic Rats. [PDF]
Tasci I, Demir CF, Kuloglu T.
europepmc +1 more source
THE FORMATION AND STRUCTURE OF MYELIN SHEATHS IN THE CENTRAL NERVOUS SYSTEM
Alan Peters
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Adult Ceramide Synthase 2 (CERS2)-deficient Mice Exhibit Myelin Sheath Defects, Cerebellar Degeneration, and Hepatocarcinomas [PDF]
Silke Imgrund+8 more
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Long‐term fasting induces a remodelling of fatty acid composition in erythrocyte membranes
Abstract Introduction Long‐term fasting (LF) activates an adaptative response to switch metabolic fuels from food glucose to lipids stored in adipose tissues. The increase in free fatty acid (FFA) oxidation during fasting triggers health benefits. We questioned if the changes in lipid metabolism during LF could affect lipids in cell membranes in humans.
Katharina Gewecke+5 more
wiley +1 more source