Results 241 to 250 of about 232,901 (341)

Prolactin Receptor Deficiency Promotes Hypomyelination in White Matter Tracts During Postnatal Central Nervous System Maturation in Mice

open access: yesGlia, Volume 74, Issue 2, February 2026.
Prolactin action is essential for proper myelination of white matter tracts during neonatal and prepubertal stages in mice. Lack of prolactin receptor (Prlr−/−) signaling leads to hypomyelination and impaired locomotor function. ABSTRACT A large wave of myelination in the central nervous system (CNS) of mammals occurs during postnatal development ...
Ana L. Ocampo‐Ruiz   +12 more
wiley   +1 more source

Myelin basic protein mRNA levels affect myelin sheath dimensions, architecture, plasticity, and density of resident glial cells. [PDF]

open access: yesGlia
Bagheri H   +30 more
europepmc   +1 more source

AMPA Receptors in NG2 Glia Differently Affect Signal Transduction in the Hippocampus and Cerebellum

open access: yesGlia, Volume 74, Issue 2, February 2026.
Stronger expression of Ca2+ permeable AMPA receptors in cerebellar versus hippocampal NG2 glia. Different expression patterns of glial AMPA receptors and auxiliary subunits in both regions. Higher efficacy of neuron‐NG2 glia synapses in the cerebellum.
Dario Tascio   +5 more
wiley   +1 more source

Astrocyte MCT1 Expression Does Not Contribute to the Axonal Degenerative Phenotype Observed With Ubiquitous MCT1 Depletion

open access: yesGlia, Volume 74, Issue 2, February 2026.
Loss of astrocytic MCT1 does not cause late onset neurodegeneration. As ubiquitous MCT1 deletion causes axonal degeneration, oligodendrocytes and potentially other cells are more prominent drivers of MCT1‐mediated metabolic support of neurons. ABSTRACT We recently reported that the loss of oligodendrocyte metabolic support through the lactate and ...
Thomas Philips   +9 more
wiley   +1 more source

Aberrant Molecular Myelin Architecture in Charcot–Marie–Tooth Disease Type 1A and Hereditary Neuropathy With Liability to Pressure Palsies

open access: yesGlia, Volume 74, Issue 2, February 2026.
PMP22 copy number variation disrupts myelin architecture at SLIs and Nodes of Ranvier. Adherens junction and axoglial domain defects are often more severe in CMT1A than HNPP. Findings support PMP22 functioning as a structural organizer of myelin. ABSTRACT Charcot–Marie–Tooth Disease Type 1A (CMT1A) and Hereditary Neuropathy with Liability to Pressure ...
Kathryn R. Moss   +3 more
wiley   +1 more source

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