Results 251 to 260 of about 232,901 (341)

A Human Model of Oligodendrocyte Development Shows MCL‐1 Influences Oligodendrocyte Morphogenesis

Glia, Volume 74, Issue 2, February 2026.
A unified model of oligodendrocyte differentiation from human embryonic stem cells revealed that MCL‐1 is critical for regulating the expression of oligodendrocyte‐related genes and the morphogenesis of myelinating oligodendrocytes. ABSTRACT Oligodendrocytes are the myelinating cells of the central nervous system.
Melanie Gil, Marina R. Hanna, Vivian Gama   +2 more
wiley   +1 more source

Cdc42 regulates schwann cell radial sorting and myelin sheath folding through NF2/merlin‐dependent and independent signaling

Glia, 2013
Li Guo, Chandra Moon, Yi Zheng, N. Ratner   +3 more
semanticscholar   +1 more source

Oligodendrocyte development and myelin sheath formation are regulated by the antagonistic interaction between the Rag-Ragulator complex and TFEB. [PDF]

Glia
Bouchard EL, Meireles AM, Talbot WS.
europepmc   +1 more source

Treadmilling Model for Plasticity of the Myelin Sheath. [PDF]

Trends Neurosci, 2019
Fields RD, Dutta DJ.
europepmc   +1 more source

Faculty Opinions recommendation of Individual oligodendrocytes have only a few hours in which to generate new myelin sheaths in vivo.

, 2013
Klaus‐Armin Nave, Hauke Werner
openalex   +2 more sources

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Identification of 3’ UTR motifs required for mRNA localization to myelin sheaths in vivo [PDF]

, 2019
Katie M. Yergert, Rebecca O’Rouke, Jacob H. Hines, Bruce Appel   +3 more
openalex   +1 more source

Mitochondrial Intercellular Transfer via Platelets After Physical Training Exerts Neuro‐Glial Protection Against Cerebral Ischemia

MedComm, Volume 7, Issue 2, February 2026.
Treadmill training protects against white matter injury and reduces cerebral infarction. Muscle‐derived mitochondrial transfer via platelets is promoted by treadmill training. Platelet transfusion emerges as a potential low‐risk therapeutic strategy for sequelae and vascular dementia.
Toshiki Inaba, Nobukazu Miyamoto, Kenichiro Hira, Chikage Kijima, Yoshifumi Miyauchi, Hai‐Bin Xu, Kazo Kanazawa, Yuji Ueno, Nobutaka Hattori   +8 more
wiley   +1 more source

Profound Cognitive Impairment as a Salient Feature of Multiple Sclerosis: A Case Report

Clinical and Experimental Neuroimmunology, Volume 17, Issue 1, February 2026.
ABSTRACT Background Cognitive impairment affects up to two‐thirds of patients with multiple sclerosis (MS); however, profound global deficits, defined as a full‐scale IQ below 70, are uncommon and rarely constitute the primary symptom. Case Presentation We describe a 27‐year‐old woman with severe multidomain cognitive impairment due to MS ...
Shota Ito, Madoka Iida, Yuki Fukami, Masahisa Katsuno   +3 more
wiley   +1 more source

Evaluation of the effectiveness and safety of ONO‐2910 for the treatment of diabetic polyneuropathy: An early Phase IIa, multicenter, randomized, placebo‐controlled, double‐blind study in Japanese patients

Journal of Diabetes Investigation, Volume 17, Issue 2, Page 310-320, February 2026.
ABSTRACT Aims/Introduction Diabetic polyneuropathy (DPN) is common in patients with diabetes. Its symptoms include pain, numbness, and impaired neurosensory function. ONO‐2910 promotes Schwann cell differentiation and is being developed for DPN. Materials and Methods This Phase IIa randomized controlled trial evaluated the effectiveness and safety of ...
Yukiko Onishi, Takeshi Osonoi, Norio Takahashi, Toru Takiguchi, Eiichiro Morishima, Yoshimasa Aso, Kenji Sekiguchi, Hideki Kamiya, Jiro Nakamura   +8 more
wiley   +1 more source