Results 251 to 260 of about 48,603 (346)

MLKL‒OPTN axis regulates herpesvirus‐induced neurological sequelae

Clinical and Translational Medicine, Volume 15, Issue 6, June 2025.
MLKL plays a significant role in regulating endosomal transport of HSV‐1 to nucleus during early stages of infection. Formation of p‐MLKL bodies during HSV‐1 infection leads to death of oligodendrocyte and subsequent demyelination. OPTN can negatively modulate MLKL levels to restrict infection and consequential oligodendrocyte death during HSV‐1 ...
Ilina Bhattacharya, Rashmi Kadam, Tejabhiram Yadavalli, Chandrashekhar D. Patil, Hemant Borase, Ipsita Volety, Sergey Kalinin, Douglas L. Feinstein, Henry C. Tseng, Deepak Shukla   +9 more
wiley   +1 more source

P4–287: Effect of GETO extract on myelin sheath structure and myelin basic protein content in the brain with AD model [PDF]

, 2006
Jinzhou Tian, Yi Xu, Jing Shi, Junxiang Yin, Sheng Shu-li, Yongyan Wang   +5 more
openalex   +1 more source

Docosahexaenoic Acid and Nervonic Acid Synergically Enhance Cognitive Memory in Normal Mice via Brain Fatty Acids Remodeling

eFood, Volume 6, Issue 3, June 2025.
1. DHA and NA can enhance memory by increasing their levels in gray and white matter. 2. DHA and NA can enhance memory by increasing their levels in gray and white matter. 3. DHA and NA combination regulate spatial memory in a dose‐specific manner. ABSTRACT Docosahexaenoic acid (DHA) and nervonic acid (NA) are the main components of brain gray and ...
Hai‐Yan Ou, Lei Feng, Rui‐Ye Chen, Hui‐Yun Lu, Shuang Cai, Zhi‐You Yang   +5 more
wiley   +1 more source

Emerging Links Between Ferroptosis and Neurodegeneration: Implications for Disease Mechanisms and Nutraceutical Interventions

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
Ferroptosis, a controlled cell death, is driven by iron and characterized by reactive oxygen species and lipid peroxidation. The impact of lipid peroxides, GSH/GPX4, and iron metabolism–targeting small molecule inhibitors is discussed. Nucleic acids, proteins, and phytochemicals are implicated as inhibitors of ferroptosis.
Anwar Ali, Quratulain Babar, Ayesha Saeed, Domenico Sergi, Nenad Naumovski, Isam A. Mohamed Ahmed, Ghalia Shamlan, Halah Abdulrahman Hafiz, Muhammad Faisal Manzoor, Joanna Trafialek, Felix Kwashie Madilo   +10 more
wiley   +1 more source

Ca ²⁺ activity signatures of myelin sheath formation and growth in vivo. [PDF]

Nat Neurosci, 2018
Baraban M, Koudelka S, Lyons DA.
europepmc   +1 more source

The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes

Glia, Volume 73, Issue 6, Page 1203-1220, June 2025.
Main Points Loss of FMRP impairs human and rat oligodendrocyte (OL) morphology in vitro. FMRP‐deficient OLs show impaired maturation when engrafted in hypomyelinated mice. Rat Fmr1 knockout OLs show a delay in myelin sheath formation in vivo. ABSTRACT The Fragile X Messenger Ribonucleoprotein (FMRP) is an RNA binding protein that regulates the ...
Vidya Ramesh, Eleni Tsoukala, Ioanna Kougianou, Zrinko Kozic, Karen Burr, Biju Viswanath, David Hampton, David Story, Bharath Kumar Reddy, Rakhi Pal, Owen Dando, Peter C. Kind, Sumantra Chattarji, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Lida Zoupi   +15 more
wiley   +1 more source

THE FORMATION AND STRUCTURE OF MYELIN SHEATHS IN THE CENTRAL NERVOUS SYSTEM

, 1960
Alan Peters
openalex   +1 more source

Unexpected Remyelination in the Absence of Matrix Metalloproteinase 7

Glia, Volume 73, Issue 6, Page 1288-1306, June 2025.
Main Points MMP7 is not essential for demyelination and remyelination in the cuprizone model. MMP7‐/‐ mice fibronectin aggregates do not accumulate in the remyelination phase. MMP7‐/‐ mice have lower levels of fibronectin and hyaluronan after chronic demyelination.
Rianne P. Gorter, Andrea J. Arreguin, Wendy Oost, Jenny C. de Jonge, Harm H. Kampinga, Sandra Amor, Holly Colognato, Wia Baron   +7 more
wiley   +1 more source

Effects of Alpha Lipoic Acid on Loss of Myelin Sheath of Sciatic Nerve in Experimentally Induced Diabetic Rats. [PDF]

Med Arch, 2018
Tasci I, Demir CF, Kuloglu T.
europepmc   +1 more source

The INO80 Chromatin Remodeling Complex Regulates Histone H2A.Z Mobility and the G1‐S Transition in Oligodendrocyte Precursors

Glia, Volume 73, Issue 6, Page 1307-1323, June 2025.
Main Points Inactivating the INO80 chromatin remodelling complex greatly extends the oligodendrocyte precursor (OP) cell cycle by prolonging G1. INO80 acts in OPs via histone H2A/H2A.Z exchange. INO80 binds the transcriptional regulator OLIG2 in OPs.
Jordan L. Wright, Yi Jiang, Stuart G. Nayar, Huiliang Li, William D. Richardson   +4 more
wiley   +1 more source