Results 291 to 300 of about 48,603 (346)
Purifying selection of the lysosomal enzymes arylsulfatase A and beta-galactocerebrosidase and their evolutionary impact on myelin integrity. [PDF]
J Lipid ResLuetzen MA +5 more
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Experimental evaluation of nerve graft orientation in a rat model: Functional and histological insights. [PDF]
Jt Dis Relat SurgErgin M +6 more
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Spatial Heterogeneity in Myelin Sheathing Impacts Signaling Reliability and Susceptibility to Injury. [PDF]
eNeuroTalidou A, Lefebvre J.
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Anisotropic properties of the myelin sheath
Acta Histochemica, 1980Form birefringence curves were determined for fixed (and unfixed rat axons before and after lipid extraction. The total detected birefringence was assumed to be due to the macromolecular array of myelin sheath components (phospholipids, cholesterol, and proteins). Unfixed nerves displayed negative form birefringence.
Alberto Costa Caseiro-Filho +3 more
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Renewal of Phospholipids in the Myelin Sheath
1976It is apparent from previous work that the major brain phospholipids are synthesized in the endoplasmic reticulum and in vivo are transferred to ‘myelin’ in both developing and mature animals (l). Nevertheless, no transfer of phospholipids from ‘microsomes’ to ‘myelin’ has been demonstrated in vitro (2), after subcellular fractionation, as it has been ...
R. M. Gould, R. M. C. Dawson
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Phagocytosis of myelin sheath fragments by dendrites
Experimental Brain Research, 1987In serial ultrathin sections of the frog spinal cord, profiles of dendritic appearance were identified that contained myelin fragment inclusions and received synaptic contacts. In a number of cases it could be established that the inclusions were derived from adjacent myelin sheaths.
Antal, Miklós, Székely, György
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Glycoproteins of myelin sheaths
Journal of Molecular Neuroscience, 1997A growing number of glycoproteins have been identified and characterized in myelin and myelin-forming cells. In addition to the major P0 glycoprotein of compact PNS myelin and the myelin-associated glycoprotein (MAG) in the periaxonal membranes of myelin-forming oligodendrocytes and Schwann cells, the list now includes peripheral myelin protein-22 (PMP-
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Science, 2001
STKE Schwann cells of the peripheral nervous system express periaxin, a cytosolic protein that contains a PDZ domain, a hallmark of adaptor proteins that assemble macromolecular signaling complexes. Mutations in the human periaxin gene cause the demyelinating neuropathy of Charcot-Marie-Tooth disease, and mice that lack functional periaxin develop a ...
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STKE Schwann cells of the peripheral nervous system express periaxin, a cytosolic protein that contains a PDZ domain, a hallmark of adaptor proteins that assemble macromolecular signaling complexes. Mutations in the human periaxin gene cause the demyelinating neuropathy of Charcot-Marie-Tooth disease, and mice that lack functional periaxin develop a ...
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Galactolipids in the formation and function of the myelin sheath
Microscopy Research and Technique, 1998Among the most abundant components of myelin are the galactolipids galactocerebroside (GalC) and sulfatide. In spite of this abundance, the roles that these molecules play in the myelin sheath are not well understood. Until recently, our concept of GalC and sulfatide functions had been principally defined by immunological and chemical perturbation ...
Brian Popko +2 more
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Arrangement of Cholesterol Molecules in the Myelin Sheath
Nature, 1962POLARIZED light studies1,2 have indicated that most or all lipid moieties of the myelin sheath are radially arranged. Finean3,4 correlated the X-ray diffraction patterns of fresh and lipid-solvent extracted myelin with known data about the form and size of lipid molecules and suggested that a phospholipid-cholesterol complex forms a part of myelin ...
J J Bubis, M Wolman
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