Results 291 to 300 of about 232,901 (341)
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1981
The presence of a myelin sheath around nerve cell bodies in some sensory ganglia was first mentioned by Wagner (1846, quoted by Munzer 1931) and Bidder (1847). However, these authors did not appreciate the exact meaning of their finding. A little later, Leydig (1851) not only described the myelin sheath enveloping the nerve cell bodies in the ...
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The presence of a myelin sheath around nerve cell bodies in some sensory ganglia was first mentioned by Wagner (1846, quoted by Munzer 1931) and Bidder (1847). However, these authors did not appreciate the exact meaning of their finding. A little later, Leydig (1851) not only described the myelin sheath enveloping the nerve cell bodies in the ...
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Oligodendrocyte calcium signaling sculpts myelin sheath morphology
2023SUMMARYMyelin is essential for rapid nerve signaling and is increasingly found to play important roles in learning and in diverse diseases of the CNS. Morphological parameters of myelin such as sheath length and thickness are regulated by neuronal activity and can precisely tune conduction velocity, but the mechanisms controlling sheath morphology are ...
Manasi Iyer +10 more
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Phagocytosis of myelin sheath fragments by dendrites
Experimental Brain Research, 1987In serial ultrathin sections of the frog spinal cord, profiles of dendritic appearance were identified that contained myelin fragment inclusions and received synaptic contacts. In a number of cases it could be established that the inclusions were derived from adjacent myelin sheaths.
M, Antal, G, Székely
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Relation between myelin sheath thickness, internode geometry, and sheath resistance
Experimental Neurology, 1986The thickness of the myelin sheath of nerve fibers was traditionally assessed solely as a function of axon caliber. Studies concerning the additional effect of variation in internode length are of relatively recent date. Carefully calibrated measurements of sheath thickness and internode geometry were used in this study to define an equation to predict
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Cell implants reconstruct myelin sheaths
BMJ, 1999Scientists have succeeded in remyelinating damaged areas of the central nervous system and restoring lost function by transplanting glial cells directly into the spinal cord of animals. This reconstruction feat, until recently thought impossible, raises hopes of finding treatments for diseases with persistent myelin loss, such as multiple sclerosis ...
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Concepts in Myelin Sheath Evolution
2001Abstract What were the evolutionary pressures that led to the recent (in evolutionary terms) invention of the morphologically complex, biochemically unique and functionally essential vertebrate myelin sheath? It is frustrating that a definitive answer to this question may remain elusive.
D R Colman, L Pedraza, M Yoshida
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Renewal of Phospholipids in the Myelin Sheath
1976It is apparent from previous work that the major brain phospholipids are synthesized in the endoplasmic reticulum and in vivo are transferred to ‘myelin’ in both developing and mature animals (l). Nevertheless, no transfer of phospholipids from ‘microsomes’ to ‘myelin’ has been demonstrated in vitro (2), after subcellular fractionation, as it has been ...
R M, Dawson, R M, Gould
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Spermidine: A constituent of the myelin sheath?
Neuroscience Letters, 1978Abstract Spermidine, an aliphatic polyamine present in high concentrations in the white matter, could act as a bivalent ligand stabilizing myelin lamellae. To seek an answer to the title's question, polyamines were extracted from the subcellular fractions of rat brain after intracerebral injection of [14C]putrescine, a precursor of spermidine ...
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Multiple Myelin Sheaths in Single Schwann Cells
Nature, 1962DURING an electron microscopic investigation of the normal structure of the trigeminal ganglion in the rat, particular attention was given to various stages of myelin sheath formation1. Frequently it was observed that two or more myelinated axons were enclosed within the cytoplasm of a single Schwann cell. Such a finding was difficult to correlate with
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Microglia regulate central nervous system myelin growth and integrity
Nature, 2022Niamh McNamara, , Irene Molina-Gonzalez
exaly