Results 301 to 310 of about 48,603 (346)
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Spermidine: A constituent of the myelin sheath?
Neuroscience Letters, 1978Abstract Spermidine, an aliphatic polyamine present in high concentrations in the white matter, could act as a bivalent ligand stabilizing myelin lamellae. To seek an answer to the title's question, polyamines were extracted from the subcellular fractions of rat brain after intracerebral injection of [14C]putrescine, a precursor of spermidine ...
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Science's STKE, 2006
The myelin sheath electrically insulates axons and makes the conductance of neuronal impulses much more efficient. Chan et al . examined how the Schwann cells begin myelination of an axon. In neuronal cultures, a cell polarity protein, Par-3, localized to where the Schwann cell meets the axon and promoted the ...
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The myelin sheath electrically insulates axons and makes the conductance of neuronal impulses much more efficient. Chan et al . examined how the Schwann cells begin myelination of an axon. In neuronal cultures, a cell polarity protein, Par-3, localized to where the Schwann cell meets the axon and promoted the ...
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Evolution of myelin sheaths: Both lamprey and hagfish lack myelin
Neuroscience Letters, 1984Modern views of agnathan phylogeny consider Petromyzoniformes and Myxiniformes to belong to distinct classes that diverged from a common ancestor at a remote period, perhaps in the lower Cambrian, greater than 600 million years ago. Both are more primitive than elasmobranchs, holocephalans and bony fishes.
Fields Rd, Moore Jk, Theodore H. Bullock
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Morphology of Cryofixed Myelin Sheath
1998The myelin sheath is formed by concentrically apposed membrane pairs and shows a regularly layered pattern of alternating light lines and dense lines. Observation of cryofixed myelin demonstrated that the structures represent aqueous spaces. All lamellae of the myelin sheath show globular aggregates of particles and these particles are corresponding ...
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1981
The presence of a myelin sheath around nerve cell bodies in some sensory ganglia was first mentioned by Wagner (1846, quoted by Munzer 1931) and Bidder (1847). However, these authors did not appreciate the exact meaning of their finding. A little later, Leydig (1851) not only described the myelin sheath enveloping the nerve cell bodies in the ...
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The presence of a myelin sheath around nerve cell bodies in some sensory ganglia was first mentioned by Wagner (1846, quoted by Munzer 1931) and Bidder (1847). However, these authors did not appreciate the exact meaning of their finding. A little later, Leydig (1851) not only described the myelin sheath enveloping the nerve cell bodies in the ...
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Function of tetraspan proteins in the myelin sheath
Current Opinion in Neurobiology, 2000During the past few years, significant advances have been made in elucidating the mechanisms by which point mutations and altered gene dosages in tetraspan genes cause neurological disease. In addition, several new myelin tetraspans have been identified that are involved in adhesion, molecular trafficking, growth regulation, and migration of ...
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Adjustment of the myelin sheath to changes in axon caliber
The Anatomical Record, 1972Abstract“Chronic” axon swellings were produced by applying a snug ligature around the sciatic nerve of rats by the fourteenth postnatal day, allowing the nerve to compress itself by its subsequent growth. The technique results in swelling of the entire myelinated fiber population proximal to the constriction, and in hypoplasia or arrested growth distal
Millicent A. Johnstone +2 more
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Calcium control of myelin sheath growth
Nature Neuroscience, 2017New studies provide compelling evidence that the number and length of myelin sheaths generated by oligodendrocytes in the CNS are controlled by local calcium levels, linking axonal activity to individual myelin sheath formation.
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Membranous bodies in the myelin sheath of Schwann cells
Cell Biology International Reports, 1980Electron microscopy of muscle biopsies of patients with paralytic scoliosis and tuberculosis of spines reveals membranous bodies in the myelin sheath of Schwann cells. On the basis of this morphological pattern and indirect biochemical evidence, it is suggested that these bodies were formed by abnormal myelin metabolism.
A.C.M.C. Yau +4 more
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Movement and structure of mitochondria in oligodendrocytes and their myelin sheaths
Glia, 2016Mitochondria play several crucial roles in the life of oligodendrocytes. During development of the myelin sheath they are essential providers of carbon skeletons and energy for lipid synthesis. During normal brain function their consumption of pyruvate will be a key determinant of how much lactate is available for oligodendrocytes to export to power ...
Benjamin G. Kopek +9 more
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