Results 101 to 110 of about 36,763 (214)

White Matter Microstructure Alterations in Older Adults With Dyslipidemia Associated With Cognitive and Locomotor Dysfunction Evaluated Using Neurite Orientation Dispersion and Density Imaging

open access: yesBrain and Behavior, Volume 15, Issue 6, June 2025.
This study used NODDI to identify white matter microstructure alterations in older adults with dyslipidemia, revealing significantly reduced neurite density in several brain regions. These reductions were linked to declines in cognitive and motor functions, suggesting that NODDI may serve as a biomarker for dyslipidemia‐related axonal degeneration ...
Zaimire Mahemuti   +12 more
wiley   +1 more source

Docosahexaenoic Acid and Nervonic Acid Synergically Enhance Cognitive Memory in Normal Mice via Brain Fatty Acids Remodeling

open access: yeseFood, Volume 6, Issue 3, June 2025.
1. DHA and NA can enhance memory by increasing their levels in gray and white matter. 2. DHA and NA can enhance memory by increasing their levels in gray and white matter. 3. DHA and NA combination regulate spatial memory in a dose‐specific manner. ABSTRACT Docosahexaenoic acid (DHA) and nervonic acid (NA) are the main components of brain gray and ...
Hai‐Yan Ou   +5 more
wiley   +1 more source

The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes

open access: yesGlia, Volume 73, Issue 6, Page 1203-1220, June 2025.
Main Points Loss of FMRP impairs human and rat oligodendrocyte (OL) morphology in vitro. FMRP‐deficient OLs show impaired maturation when engrafted in hypomyelinated mice. Rat Fmr1 knockout OLs show a delay in myelin sheath formation in vivo. ABSTRACT The Fragile X Messenger Ribonucleoprotein (FMRP) is an RNA binding protein that regulates the ...
Vidya Ramesh   +15 more
wiley   +1 more source

The Role of Proton Magnetic Resonance Spectroscopy in Neonatal and Fetal Brain Research

open access: yesJournal of Magnetic Resonance Imaging, Volume 61, Issue 6, Page 2404-2424, June 2025.
The biochemical composition and structure of the brain are in a rapid change during the exuberant stage of fetal and neonatal development. 1H‐MRS is a noninvasive tool that can evaluate brain metabolites in healthy fetuses and infants as well as those with neurological diseases.
Steve C.N. Hui   +2 more
wiley   +1 more source

Considerations and recommendations from the ISMRM diffusion study group for preclinical diffusion MRI: Part 1: In vivo small‐animal imaging

open access: yesMagnetic Resonance in Medicine, Volume 93, Issue 6, Page 2507-2534, June 2025.
Abstract Small‐animal diffusion MRI (dMRI) has been used for methodological development and validation, characterizing the biological basis of diffusion phenomena, and comparative anatomy. The steps from animal setup and monitoring, to acquisition, analysis, and interpretation are complex, with many decisions that may ultimately affect what questions ...
Ileana O. Jelescu   +56 more
wiley   +1 more source

Partial regression of peripapillary myelinated nerve fibers after non-arteritic anterior ischemic optic neuropathy. [PDF]

open access: yesArq Bras Oftalmol
Negrete FJM   +5 more
europepmc   +1 more source

Diffusion tensor subspace imaging of double diffusion–encoded MRI delineates small fibers and gray‐matter microstructure not visible with single encoding techniques

open access: yesMagnetic Resonance in Medicine, Volume 93, Issue 6, Page 2370-2385, June 2025.
Abstract Purpose Double diffusion encoding (DDE) acquisition strategies promise specificity for small‐dimensional structures inaccessible to single diffusion encoding (SDE). For DDE‐weighted MRI scans to become relevant for whole brain imaging, signal reconstruction frameworks must accurately report microstructural features of interest—especially ...
Elizabeth B. Hutchinson   +8 more
wiley   +1 more source

Sensory Nerve Action Potential Analysis in a Cohort of Patients With Spinal Muscular Atrophy Aged 12 Years and Older

open access: yesMuscle &Nerve, Volume 71, Issue 6, Page 1016-1024, June 2025.
ABSTRACT Introduction/Aims Survival Motor Neuron 1 (SMN1)‐related spinal muscular atrophy (SMA) is characterized by α‐motor neuron degeneration, with sensory function assumed to be clinically preserved. However, recent studies in severely affected patients and animal models have challenged this view.
Leandra A. A. Ros   +7 more
wiley   +1 more source

CORONIS symposium 2023: Scientific and clinical frontiers in ocular surface innervation

open access: yesActa Ophthalmologica, Volume 103, Issue 4, Page e240-e255, June 2025.
Abstract The 5th CORONIS Symposium, held during the 2023 Congress of the European Association for Vision and Eye Research (EVER), highlighted the growing importance of ocular surface innervation in eye surface disorders. This article summarises the insights and perspectives shared during the symposium, which focused on the clinical relevance of ocular ...
Anat Galor   +10 more
wiley   +1 more source

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