Results 141 to 150 of about 39,707 (258)

Autosomal Recessive Spastic Ataxia of Charlevoix‐Saguenay in Two Half‐Siblings

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 413-417, February 2026.
ABSTRACT Autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) is caused by biallelic pathogenic variants in the SACS gene. We report the clinical, radiologic and neurophysiologic features of a pair of half‐siblings who presented with progressive cerebellar ataxia, peripheral neuropathy and upper motor neuron signs.
Dennis Yeow   +6 more
wiley   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha   +12 more
wiley   +1 more source

Distribution of Voltage‐Gated Sodium Channels and Scaffolding Proteins on Vestibular Calyx Ending Delineates the Axon Initial Segment

open access: yesJournal of Comparative Neurology, Volume 534, Issue 2, February 2026.
Various sodium channel isoforms and their scaffolding proteins are found in four different microdomains in vestibular calyx‐bearing afferents. These microdomains serve different purposes, analogous to the heminode, axon initial segment, and synaptic domains of other types of sensory afferents.
Anna Lysakowski   +8 more
wiley   +1 more source

Extensive myelinated nerve fibers in eye with colobomatous optic disk.

open access: yesIndian J Ophthalmol, 2020
Hirawat RS, Nagesha CK, Divakar MM.
europepmc   +1 more source

AMPA Receptors in NG2 Glia Differently Affect Signal Transduction in the Hippocampus and Cerebellum

open access: yesGlia, Volume 74, Issue 2, February 2026.
Stronger expression of Ca2+ permeable AMPA receptors in cerebellar versus hippocampal NG2 glia. Different expression patterns of glial AMPA receptors and auxiliary subunits in both regions. Higher efficacy of neuron‐NG2 glia synapses in the cerebellum.
Dario Tascio   +5 more
wiley   +1 more source

Nuclei discovered new practical insights via optimized soliton-like pulse analysis in a space fractional-time beta-derivatives equations

open access: yesScientific Reports
Nerve signal conduction, and particularly in myelinated nerve fibers, is a highly dynamic phenomenon that is affected by various biological and physical factors.
Emmanuel Fendzi-Donfack   +10 more
doaj   +1 more source

Acute Intermittent Hypoxia Exerts Beneficial Effects and Promotes Repair in Male Mice in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

open access: yesGlia, Volume 74, Issue 2, February 2026.
Acute intermittent hypoxia is a novel, noninvasive therapy that shows promising and similar beneficial repair and remyelination following demyelination in male experimental autoimmune encephalomyelitis, as was previously shown in female mice. ABSTRACT Multiple sclerosis (MS) affects women more frequently than men, but the disease progresses more ...
Nataliya Tokarska   +6 more
wiley   +1 more source

A Human Model of Oligodendrocyte Development Shows MCL‐1 Influences Oligodendrocyte Morphogenesis

open access: yesGlia, Volume 74, Issue 2, February 2026.
A unified model of oligodendrocyte differentiation from human embryonic stem cells revealed that MCL‐1 is critical for regulating the expression of oligodendrocyte‐related genes and the morphogenesis of myelinating oligodendrocytes. ABSTRACT Oligodendrocytes are the myelinating cells of the central nervous system.
Melanie Gil   +2 more
wiley   +1 more source

Quad‐SPIM: A High‐Speed, Multi‐Color Light‐Sheet Microscope for 3D Imaging of Large Cleared Human Brain Tissues

open access: yesLaser &Photonics Reviews, Volume 20, Issue 3, 5 February 2026.
A high‐speed, multi‐color light‐sheet microscope, named quad‐SPIM, enables rapid three dimensional (3D) imaging of large cleared human brain samples with simultaneous four‐channel acquisition. This custom‐built system achieves subcellular resolution across centimeter‐scale volumes, maintaining high image quality.
Laura Perego   +11 more
wiley   +1 more source

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