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Physiology and pathophysiology of myelinated nerve fibers

2013
The chief role of the axon is that of impulse conduction, which depends on the electrical cable structure and voltage-dependent ion channels of the axonal membrane. Over recent decades, the development of specialized techniques such as patch clamping and site-directed mutagenesis have established the contribution of neuronal ion channel function to the
Ryuji Kaji, Matthew C. Kiernan
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Measurement of the Action Potential of Myelinated Nerve Fiber

American Journal of Physiology-Legacy Content, 1955
THE PEAK VALUE of the action potential of the vertebrate myelinated fiber has been previously recorded by a number of investigators. (1-5 and others). Values range from about 60-155 mv depending on the method employed. These methods may be divided into three general categories.
I. Tasaki, K. Frank
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Organization of Ion Channels in the Myelinated Nerve Fiber

Science, 1985
The functional organization of the mammalian myelinated nerve fiber is complex and elegant. In contrast to nonmyelinated axons, whose membranes have a relatively uniform structure, the mammalian myelinated axon exhibits a high degree of regional specialization that extends to the location of voltage-dependent ion channels within the axon membrane ...
J. M. Ritchie, Stephen G. Waxman
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MYELINATED NERVE FIBERS AND RETINAL VASCULAR ABNORMALITIES

Retina, 1996
Abnormal retinal vessels may develop in a region of myelinated nerve fibers, and these vessels may cause vitreous hemorrhages.The clinical histories of seven patients with retinovascular abnormalities in a patch of myelinated nerve fibers are presented. None of the reported patients had other evidence of systemic disease.
Leys Mj   +7 more
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A model of injury potential for myelinated nerve fiber

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2015
Excellent models have been described in literatures which related membrane potential to extracellular electric or magnetic stimulation and which described the formation and propagation of action potentials along the axon, for both myelinated and nonmyelinated fibers.
Wang Aihua   +4 more
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Progression of Retinal Nerve Fiber Myelination in Childhood

American Journal of Ophthalmology, 1994
Myelination of the visual pathway has been demonstrated to occur by as early as 32 weeks of gestation and continues for several years into early childhood. In most cases, the process of myelination does not extend beyond the lamina cribrosa. We studied a boy with progressive myelination that extended beyond the lamina cribrosa to the retinal nerve ...
Baber H. Ali   +4 more
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Myelinated nerve fiber antenna model activation

2016 24th International Conference on Software, Telecommunications and Computer Networks (SoftCOM), 2016
A myelinated nerve fiber is modeled as a straight thin wire antenna and stimulated by a current generator at the fiber beginning. The model is based on the corresponding homogenous Pocklington integro-differential equation for the perfectly conducting wire in a lossy unbounded homogenous space, where the activated node of Ranvier is modeled as a thin ...
Vicko Doric, Dragan Poljak, Ivana Zulim
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Antenna model for passive myelinated nerve fiber

2015 23rd International Conference on Software, Telecommunications and Computer Networks (SoftCOM), 2015
A myelinated nerve fiber, stimulated by a current generator at the fiber beginning, is modeled as a straight thin wire antenna. The model is based on the corresponding Pocklington integro-differential equation for the perfectly conducting wire in a lossy unbounded homogenous space.
Khalil El Khamlichi Drissi   +3 more
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In Vivo Studies of Myelinated Nerve Fibers

1964
Publisher Summary From the standpoint of both structure and function the myelinated nerve fiber is a highly specialized component of the nervous system. It represents a very intimate association of a nerve cell process with a satellite myelinating cell.
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Transmission-Line Model for Myelinated Nerve Fiber

2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005
Herein, the well-known cable equation for non-myelinated axon model is extended analytically for myelinated axon formulation. The classical cable equation is thereby modified into a linear second order ordinary differential equation with periodic coefficient, known as Hill's equation.
P.D. Einziger   +2 more
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