Results 31 to 40 of about 36,763 (214)
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
Advanced Science, EarlyView.This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang +9 more
wiley +1 more source
The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog [PDF]
, 2006 We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Jessen, KR +6 more
core
Advanced Science, EarlyView.This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song +15 more
wiley +1 more source
Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study
Annals of Neurology, EarlyView.Objective Investigate the immune system's role in cluster headache by analyzing cytokines in people with cluster headache and headache‐free controls, and explore if certain cytokines could predict a specific phenotype. Methods We measured 45 cytokines in adult participants from the Danish Cluster Headache Biobank in a prospective case–control setup ...
Nunu Laura Timotheussen Lund +6 more
wiley +1 more source
The Anatomical Record, EarlyView.Bioimaging of the sense organs and brain of fishes and reptiles. Left panel: 3D reconstruction of the head and brain of the deep‐sea viperfish Chauliodus sloani following diceCT. Right panel: A 3D reconstruction of a 70‐day‐old embryo head of the bearded dragon Pogona vitticeps following diceCT, showing the position of the segmented brain within the ...
Shaun P. Collin +9 more
wiley +1 more source
Simulation of activation and propagation delay during tripolar neural stimulation [PDF]
, 1993 Computer simulations were perfonned to investigate the influence of stimulus amplitude on cathodal activation delay, propagation delay and blocking during stimulation with a bipolar cuff electrode.
Goodall, Eleanor V. +3 more
core +2 more sources
Restrained Eating Features and Brain Morphology: A Pediatric Population‐Based Study
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Anorexia nervosa, a restrictive eating disorder that is most commonly seen in females, is associated with alterations in gray matter (GM) and white matter (WM) structures. However, little is known about how restrained eating (RE) and the body mass index‐standard deviation score (BMI‐SDS) are related to brain morphology and whether ...
C. P. M. Steegers +6 more
wiley +1 more source
The Cutaneous Biopsy for the Diagnosis of Peripheral Neuropathies: Meissner’s Corpuscles and Merkel’s Cells [PDF]
, 2018 Cutaneous biopsy is a complementary method, alternative to peripheral nerve biopsy, for the analysis of nerve involvement in peripheral neuropathies, systemic diseases, and several pathologies of the central nervous system.
Alba, Elda +8 more
core +2 more sources
Exploration, EarlyView.Targeting mitochondrial dysfunction presents a potential therapeutic approach for treating spinal cord injury. We have successfully designed and synthesized a functional Se@NADH nanodrug system. This system offers neuroprotective and neuroregenerative benefits by modulating mitochondrial function and neutralizing reactive oxygen species, thereby ...
Guibin Gao +12 more
wiley +1 more source
Setting reference level in the human safety guidelines via nerve activation intercomparison at IF [PDF]
, 2019 International guidelines/standards have been published for human protection from electromagnetic field exposure. The research in the intermediate frequencies (IF: 300 Hz-10 MHz) is scattered unlike for other frequencies, and thus the limit prescribed in ...
Gomez-Tames, Jose +7 more
core +2 more sources