Results 41 to 50 of about 36,763 (214)

Oligodendrogenesis in Evolution, Development and Adulthood

open access: yesGlia, EarlyView.
Oligodendrocytes and myelin took shape in jawed vertebrates. During development, OPCs are originated from NSCs and then undergo differentiation into mature oligodendrocytes that supply myelin. OPCs persist in the adult CNS and continue to produce oligodendrocytes and myelin. Adaptive myelination, which fine‐tunes neural circuits in response to neuronal
Hao Hu   +3 more
wiley   +1 more source

Morphometric study of the nerve fibers of the oculomotor nerve in dog [PDF]

open access: yes, 2007
The intracranial portion of the right oculomotor nerves was extracted from six adult German Shepherd dogs. The nerves were studied using light and electron microscopy.
Agüera Carmona, Eduardo   +6 more
core  

Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling

open access: yesGlia, EarlyView.
Brain oligodendrocytes have lower rates of cholesterol synthesis and higher rates of lipoprotein uptake than spinal cord oligodendrocytes. Myelin lipid content is higher in CNS regions with larger average axon diameter. Brain and spinal cord myelin cholesterol content is innately different, while myelin fatty acid content can be modulated by fiber ...
Marie L. Mather   +4 more
wiley   +1 more source

New Approaches Based on Serial-Block Face Electron Microscopy to Investigate the Peripheral Nervous System. [PDF]

open access: yesJ Peripher Nerv Syst
ABSTRACT Background and Aims Serial block face scanning electron microscopy (SBF‐SEM) enables automated 3D imaging of specimens with ultrastructural resolution. However, its application is often restricted due to the complex and labor‐intensive nature of the processes involved.
Borisovs V   +4 more
europepmc   +2 more sources

AxonDeepSeg: automatic axon and myelin segmentation from microscopy data using convolutional neural networks [PDF]

open access: yes, 2017
Segmentation of axon and myelin from microscopy images of the nervous system provides useful quantitative information about the tissue microstructure, such as axon density and myelin thickness. This could be used for instance to document cell morphometry
Antonsanti, Pierre-Louis   +5 more
core   +3 more sources

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

open access: yesIbrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li   +10 more
wiley   +1 more source

The rise of 3D bioprinting advancements in modeling neurodegenerative diseases

open access: yesIbrain, EarlyView.
Modeling neurodegenerative diseases: 3D bioprinting as a strategy for replicating the complexity of brain architecture. Recent findings have demonstrated that 3D bioprinting platforms can be exploited to recreate the complex neural pattern, giving the possibility of controlling cell density and scaffold stiffness.
Lucia Iafrate, Gianluca Cidonio
wiley   +1 more source

On axoplasmic pressure waves and their possible role in nerve impulse propagation

open access: yes, 2010
It is suggested that the propagation of the action potential is accompanied by an axoplasmic pressure pulse propagating in the axoplasm along the axon length.
Rvachev, Marat M.
core   +1 more source

Neurotrophin-3-enhanced nerve regeneration selectively improves recovery of muscle fibers expressing myosin heavy chains 2b [PDF]

open access: yes, 1997
The purpose of this study was to evaluate the effect of neurotrophin 3 (NT-3) enhanced nerve regeneration on the reinnervation of a target muscle. Muscle fibers can be classified according to their mechanical properties and myosin heavy chain (MHC ...
Airaksinen   +48 more
core   +2 more sources

Nanomaterials for promoting axon regeneration after spinal cord injury: Mechanisms and prospects

open access: yesInterdisciplinary Medicine, EarlyView.
The effects of clinical therapies for spinal cord injury (SCI) are greatly limited due to poor axon regeneration. This review systematically discusses the ability of nanomaterials (NMs) to treat SCI and the mechanism underlying their therapeutic effects. The properties of NMs that are conducive to axon regeneration after SCI are outlined.
Jia Liu   +9 more
wiley   +1 more source

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