Results 211 to 220 of about 42,337 (292)

Drug development in higher-risk myelodysplastic syndromes. [PDF]

Blood Cancer J
Venugopal S, Sekeres MA.
europepmc   +1 more source

The Intersection of Lynch Syndrome and Hematological Malignancies: A Rare Short Report

eJHaem, Volume 6, Issue 4, August 2025.
ABSTRACT Lynch syndrome (LS), which is an autosomal dominant disorder caused primarily by germline pathogenic variants of mismatch repair (MMR) genes, cases a number of malignancies. Hematologic malignancies are not included as related tumors of LS because it has not yet been established whether the carcinogenesis of hematologic malignancies is ...
Tomomi Oka, Takeshi Nakajima, Makoto Iwasaki, June Takeda, Masako Torishima, Maki Sakurada, Takuya Shimizu, Takero Shindo, Masakazu Fujimoto, Shinya Otsuki, Hironori Haga, Kokichi Sugano, Miho Ando, Chisaki Mizumoto, Junya Kanda, Yasuhito Nannya, Seishi Ogawa, Akifumi Takaori‐Kondo, Shinji Kosugi   +18 more
wiley   +1 more source

Oxidative Stress and Its Role in the Emergence and Progression of Myelodysplastic Syndromes: Insights from Proteomic Analysis and Other Methodologies. [PDF]

Proteomes
Boura-Theodorou A, Psatha K, Maniatsi S, Kourti A, Kaiafa G, Aivaliotis M, Makedou K.   +6 more
europepmc   +1 more source

Analysis of Late Complications Associated With Hematopoietic Stem Cell Transplantation in Patients With Dyskeratosis Congenita

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Dyskeratosis congenita (DKC) is a genetic disorder frequently complicated by bone marrow failure (BMF). Hematopoietic stem cell transplantation (HSCT) remains the only curative treatment option for BMF in DKC. However, late complications of DKC, especially pulmonary fibrosis (PF), pose significant challenges.
Takashi Koike, Shohei Yamamoto, Mayuko Shibata, Kohei Otsuka, Yumiko Sugishita, Ryota Kaneko, Naoko Kawabata, Sachio Fujita, Kosuke Akiyama, Daisuke Toyama, Miharu Yabe, Atsushi Uchiyama, Hiromasa Yabe   +12 more
wiley   +1 more source

Prognostic impact of somatic mutations and additional chromosomal abnormalities in patients with myelodysplastic syndromes and chromosome 20q deletion. [PDF]

Clin Exp Med
Huang X, Li X, Liu Q, Guo J, Chen J, Zhou L, Song L, Zhang Z, Su J, Zhang Y, Yan M, He Q, Wu D, Xu F, Chang C, Wu L.   +15 more
europepmc   +1 more source

A Case of Myelodysplastic Syndrome Associated with IgA Nephropathy.

, 1999
Shintaro Hayashi, Toyohiro Okada, Hisashi Tsutsumi, T Kumakawa, Mayumi Mori   +4 more
openalex   +2 more sources

Effects of a Low Versus Moderate–High Intense Exercise Program on Innate Immune Recovery, Fitness, and Quality of Life During Pediatric Allo‐HSCT—The ANIMAL Exploratory Randomized Controlled Trial

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Objectives Pediatric cancer patients undergoing allogeneic hematopoietic stem cell transplantation (allo‐HSCT) are severely immunosuppressed leading to a high risk for life‐threatening infections. This trial investigates the effects of exercise during allo‐HSCT on immune cell recovery and patient‐related outcomes (DRKS00019865). Methods Twenty‐
Ronja Beller, Sabrina B. Bennstein, Dirk Reinhardt, Gabriele Gauß, Carolina Chamorra Vina, Helmut Hanenberg, Markus Uhrberg, Miriam Götte   +7 more
wiley   +1 more source

Allogeneic Stem Cell Transplantation: The Relevance of Conditioning Regime Intensity for Myelodysplastic Syndromes (MDS). [PDF]

Curr Oncol
Berg T, Salter B, Radford M, Chen HTT, Leber B.   +4 more
europepmc   +1 more source

Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley   +1 more source

STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromes. [PDF]

Neoplasia
King Z, Desai SR, Frank DA, Shastri A.
europepmc   +1 more source