Results 41 to 50 of about 51,886 (205)

Cytogenetic studies of Brazilian pediatric myelodysplastic syndrome cases: challenges and difficulties in a large and emerging country [PDF]

, 2013
Myelodysplastic syndromes (MDS) and juvenile myelomonocytic leukemia (JMML) are rare hematopoietic stem cell diseases affecting children. Cytogenetics plays an important role in the diagnosis of these diseases.
Chauffaille, Maria de Lourdes, Gaiolla, R. D., Lopes, L. F., Pelicario, L. M., Tanizawa, Roberta Sandra da Silva, Toledo, Silvia Regina Caminada de, Velloso, Elvira Deolinda Rodrigues Pereira   +6 more
core   +1 more source

Treatment and outcomes for chronic myelomonocytic leukemia compared to myelodysplastic syndromes in older adults

Haematologica, 2013
Prior studies have investigated patients' characteristics, treatments, and outcomes for older adults with myelodysplastic syndromes, but most failed to distinguish chronic myelomonocytic leukemia. Recognizing potentially important differences between the
Dan P. Zandberg, Ting-Ying Huang, Xuehua Ke, Maria R. Baer, Steven D. Gore, Sheila Weiss Smith, Amy J. Davidoff   +6 more
doaj   +1 more source

Myelodysplasia in a psoriasis patient receiving etanercept : Cause or coincidence? [PDF]

, 2018
Peer reviewedFinal Accepted ...
Ayoub, Othman Hadi, Dawoud, Dalia M, Dawoud, Noha Mohammed, Essa, Enas Said   +3 more
core   +3 more sources

Molecular similarity between myelodysplastic form of chronic myelomonocytic leukemia and refractory anemia with ring sideroblasts

Haematologica, 2013
Chronic myelomonocytic leukemia is similar to but a separate entity from both myeloproliferative neoplasms and myelodysplastic syndromes, and shows either myeloproliferative or myelodysplastic features.
Véronique Gelsi-Boyer, Nathalie Cervera, François Bertucci, Mandy Brecqueville, Pascal Finetti, Anne Murati, Christine Arnoulet, Marie-Joelle Mozziconacci, Ken I. Mills, Nicholas C. P. Cross, Norbert Vey, Daniel Birnbaum   +11 more
doaj   +1 more source

Genomic analysis of bone marrow failure and myelodysplastic syndromes reveals phenotypic and diagnostic complexity

Haematologica, 2015
Accurate and timely diagnosis of inherited bone marrow failure and inherited myelodysplastic syndromes is essential to guide clinical management. Distinguishing inherited from acquired bone marrow failure/myelodysplastic syndrome poses a significant ...
Michael Y. Zhang, Siobán B. Keel, Tom Walsh, Ming K. Lee, Suleyman Gulsuner, Amanda C. Watts, Colin C. Pritchard, Stephen J. Salipante, Michael R. Jeng, Inga Hofmann, David A. Williams, Mark D. Fleming, Janis L. Abkowitz, Mary-Claire King, Akiko Shimamura   +14 more
doaj   +1 more source

Comparison of genetic and clinical aspects in patients with acute myeloid leukemia and myelodysplastic syndromes all with more than 50% of bone marrow erythropoietic cells

Haematologica, 2011
Background The World Health Organization separates acute erythroid leukemia (erythropoiesis in ≥50% of nucleated bone marrow cells; ≥20% myeloblasts of non-erythroid cells) from other entities with increased erythropoiesis – acute myeloid leukemia with ...
Ulrike Bacher, Claudia Haferlach, Tamara Alpermann, Wolfgang Kern, Susanne Schnittger, Torsten Haferlach   +5 more
doaj   +1 more source

Gender effects on cytidine analogue metabolism and myelodysplastic syndrome treatment outcomes [PDF]

, 2012
In vivo, half-lives of cytidine analogues such as 5-azacytidine and decitabine, used to treat myelodysplastic syndromes (MDS), are determined largely by cytidine deaminase (CDA), an enzyme that rapidly metabolizes these drugs into inactive uridine ...
Ania Jankowska, Jaroslaw Maciejewski, Joseph Covey, Kenneth Chan, Kory Engelke, Mikkael Sekeres, Pramod Terse, Quteba Ebrahem, Ramon Tiu, Reda Mahfouz, Tomas Radivoyevitch, Yogen Saunthararajah, Yonghua Ling, Zhenbo Hu   +13 more
core   +1 more source

Reproducibility of the World Health Organization 2008 criteria for myelodysplastic syndromes [PDF]

, 2013
The reproducibility of the World Health Organization 2008 classification for myelodysplastic syndromes is uncertain and its assessment was the major aim of this study.
Arenillas, Leonor, Florensa Brichs, Lourdes, Luño Fernández, Elisa, Ruiz, Juan C., Sanz, Guillermo, Senent, Leonor, Spanish MDS Cooperat Grp GESMD   +6 more
core   +1 more source

SRSF2 Is Essential For Hematopoiesis and Its Mutations Dysregulate Alternative RNA Splicing In MDS [PDF]

, 2013
Myelodysplastic syndromes (MDS) are a group of neoplasms that are ineffective in generating multiple lineages of myeloid cells and have various risks to progress to acute myeloid leukemia.
Chen, Liang, Dekelver, Russell, Fu, Xiang-Dong, Heuser, Michael, Komeno, Yukiko, Lin, Leo, Monterroza, Dora D, Qiu, Jinsong, Thol, Felicitas, Xu, YiJun, Zhang, Dong-Er   +10 more
core  

Value of infliximab (Remicade) in patients with low-risk myelodysplastic syndrome. Final results of a randomized phase II trial (EORTC trial 06023) of the EORTC Leukemia Group [PDF]

, 2011
peer reviewedTumor-necrosis factor alpha activity has been correlated to ineffective erythropoiesis in lower risk myelodysplastic syndromes. Infliximab (Remicade) is an anti-tumor-necrosis factor alpha chimeric antibody that is used in the treatment of ...
Amadori, Sergio, Baron, Frédéric, De Witte, Theo, Delforge, Michel, Denzlinger, Claudio, Indrak, Karel, Muus, Petra, Ossenkoppele, Geert, Selleslag, Dominik, Suciu, Stefan, Thyss, Antoine, Zwierzina, Heinz   +11 more
core   +2 more sources