Results 61 to 70 of about 9,231 (199)

European Bone Marrow Working Group trial on reproducibility of World Health Organization criteria to discriminate essential thrombocythemia from prefibrotic primary myelofibrosis

Haematologica, 2012
Background The World Health Organization classification of myeloproliferative neoplasms discriminates between essential thrombocythemia and the prefibrotic phase of primary myelofibrosis.
Thomas Buhr, Konnie Hebeda, Vassiliki Kaloutsi, Anna Porwit, Jon Van der Walt, Hans Kreipe   +5 more
doaj   +1 more source

Osteogenic Potential of Mesenchymal Stromal Cells Contributes to Primary Myelofibrosis. [PDF]

, 2015
International audiencePrimary myelofibrosis is a myeloproliferative neoplasm that is a precursor to myeloid leukemia. Dysmegakaryopoiesis and extramedullary hematopoiesis characterize primary myelofibrosis, which is also associated with bone marrow ...
Torossian, Frédéric, Rochet, Nathalie, Pieri, Lisa, de Revel, Thierry, Martinaud, Christophe, Henault, Emilie, Golub, Rachel, Guerton, Bernadette, Albanese, Patricia, Lataillade, Jean-Jacques, Schmutz, Sandrine, Dupriez, Brigitte, Souraud, Jean-Baptiste, Ianotto, Jean-Christophe, Desterke, Christophe, Pierre-Louis, Olivier, Konopacki, Johanna, Vannucchi, Alessandro M, Anginot, Adrienne, Bourgeade, Marie-Françoise, Le Bousse-Kerdilès, Marie-Caroline, Vannucchi, Alessandro Maria   +21 more
core   +1 more source

Prospective phase I study of nivolumab to promote graft‐versus‐tumour in relapsed or refractory haematological malignancy post allogeneic haematopoietic stem cell transplantation

British Journal of Haematology, EarlyView.
Baseline immunophenotype and gene expression predict suitability for salvage nivolumab in patients with relapsed/refractory haematological malignancy. Summary Allogeneic haematopoietic stem cell transplantation (alloHSCT) relies on donor‐derived T cells to mediate the graft‐versus‐tumour (GVT) effect, but relapse may result from impaired immune ...
Trung Q. Ngo, Eric Wong, Joanne E. Davis, Mandy Ludford‐Menting, Jessica Klass, Sara K. Dohrmann, Rachel Koldej, David Ritchie   +7 more
wiley   +1 more source

Digital PCR - Methods and Protocols

European Journal of Histochemistry, 2019
Sensitivity, reproducibility, precision and accuracy are recurring words in this book. Indeed, digital PCR (dPCR) represents a major step forward in the quantification of nucleic acids. In this field, for many years it has been used the quantitative PCR (
Paolo Catarsi
doaj   +1 more source

Amyloidosis complicating idiopathic myelofibrosis.

, 1999
An 84-year-old man presented with ankle edema, significant proteinuria, and mild impairment of renal function soon after treatment was started for idiopathic myelofibrosis. Renal amyloidosis was found on biopsy.
Ho, CP, Chan, KW
core   +1 more source

Myelofibrosis patients in Belgium : disease characteristics [PDF]

, 2014
Objective: To date, only a small number of epidemiological studies on myelofibrosis have been performed. The current study aimed to characterize the myelofibrosis patient population in Belgium according to predefined disease parameters (diagnosis, risk ...
Devos, Thibaut, Pierre, Pascal, Pierre, P., Zachee, P., Trullemans, F, Bron, D., Lemmens, Jan, Van Droogenbroeck, Jan, Van Droogenbroeck, J, Beguin, Y, Devos, T., Van Eygen, K., Mineur, Philippe, Bron, D, Pierre, P, Berneman, Zwi, Benghiat, FS, Chatelain, Christian, Pluymers, Wim, Demuynck, H., Benghiat, F. S., Chatelain, C, Van Eygen, K, Theunissen, Koen, Pluymers, W, Droogenbroeck, Jan Van, Beguin, Yves, Zachée, Pierre, Lemmens, J, Zachée, P, Devos, Timothy, Kentos, A, Berneman, Z, Lemmens, J., Demuynck, H, Trullemans, Fabienne, Benghiat, Fleur, Pluymers, W., Kentos, A., Kentos, Alain, Beguin, Y., Mineur, P, Noens, L., Noens, Lucien, Knoops, L., Knoops, L, Bermeman, Zwi Nisan, Van Droogenbroeck, J., Benghiat, Fleur S, Bron, Domonique, Trullemans, F., Van Eygen, Koen, Mineur, P., Benghiat, Fleur Samantha, Bron, Dominique, Demuynck, Hilde, Chatelain, C., Theunissen, K, Theunissen, K., Devos, T, Theunidden, Koen, Knoops, Laurent, Eygen, Koen Van, Eygen, Koen V, Berneman, Z.   +64 more
core   +1 more source

Treatment Algorithm for Primary and Secondary Myelofibrosis

, 2023
The management of primary myelofibrosis (PMF), postpolycythemia vera myelofibrosis (PPV-MF), and postessential thrombocythemia (PET-MF) is driven by their clinicopathologic and genomic characteristics, and their risk categories.
Gill, Harinder, Leung, Garret
core   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

European Journal of Haematology, EarlyView.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto, Silvia Sorella, Erminia Baldacci, Massimo Breccia, Sabina Chiaretti, Marcello Capriata, Livia Donzelli, Gianna Maria D'Elia, Salvatore Giacomo Morano, Ilaria Del Giudice, Maurizio Martelli, Cristina Santoro, Antonio Chistolini   +12 more
wiley   +1 more source

P982: MYELOID-DERIVED SUPPRESSOR CELLS: CHARACTERIZATION IN PERIPHERAL BLOOD AND SPLEEN TISSUE OF PATIENTS WITH MYELOFIBROSIS

HemaSphere, 2022
R. Campanelli, A. Bonometti, M. Massa, C. Abbà, L. Villani, A. Carolei, P. Catarsi, M. Paulli, G. Barosi, E. Boveri, V. Rosti   +10 more
doaj   +1 more source

Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and ZFP36L1 as a potential tumor suppressor gene that is epigenetically regulated

Haematologica, 2019
In this study we interrogated the DNA methylome of myelofibrosis patients using high-density DNA methylation arrays. We detected 35,215 differentially methylated CpG, corresponding to 10,253 genes, between myelofibrosis patients and healthy controls ...
Nicolás Martínez-Calle, Marien Pascual, Raquel Ordoñez, Edurne San José Enériz, Marta Kulis, Estíbaliz Miranda, Elisabeth Guruceaga, Víctor Segura, María José Larráyoz, Beatriz Bellosillo, María José Calasanz, Carles Besses, José Rifón, José I. Martín-Subero, Xabier Agirre, Felipe Prosper   +15 more
doaj   +1 more source