Results 81 to 90 of about 38,413 (282)
Abstract The clinical and immunophenotypic attributes of reactive γδ T‐cell expansions are less well characterized than their malignant counterparts, which can pose diagnostic challenges. This study aims to investigate the characteristics and long‐term clinical outcomes of reactive γδ T‐cell expansions.
Hamza Tariq+6 more
wiley +1 more source
Introduction Idiopathic myelofibrosis is a chronic myeloproliferative disorder characterized by leukoerythroblastosis, massive splenomegaly, and increases in the reticular and collagen fibers in the bone marrow.
Yamashina Shunhei+5 more
doaj +1 more source
Patterns of survival among patients with myeloproliferative neoplasms diagnosed in Sweden from 1973 to 2008: a population-based study. [PDF]
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field.Reported survival in patients with myeloproliferative neoplasms (MPNs) shows great variation.
Andersson, Therese M-L+7 more
core +1 more source
Outcome of Transplantation for Myelofibrosis
Myelofibrosis is a myeloproliferative disorder incurable with conventional strategies. Several small series have reported long-term disease-free survival (DSF) after allogeneic hematopoietic cell transplantation (HCT). In this study, we analyze the outcomes of 289 patients receiving allogeneic transplantation for primary myelofibrosis between 1989 and ...
Theresa Hahn+23 more
openaire +3 more sources
Digital PCR - Methods and Protocols
Sensitivity, reproducibility, precision and accuracy are recurring words in this book. Indeed, digital PCR (dPCR) represents a major step forward in the quantification of nucleic acids. In this field, for many years it has been used the quantitative PCR (
Paolo Catarsi
doaj +1 more source
JAK2 V617F Analysis in Indonesian Myeloproliferative Neoplasms Patients [PDF]
Background : Three subtypes of myeloproliferative neoplasms (MPNs): Polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) showed overlapping phenotype.
Faradz, S. M. (Sultana)+2 more
core +3 more sources
Retroperitoneal extramedullary hematopoietic pseudotumor in ataxia-telangiectasia. [PDF]
Ataxia-telangiectasia confers a significant increase in the development of several cancer types, most commonly leukemia and lymphoma. However, as the natural history for these patients is evolving and their lifespan is increasing, there is the potential ...
Bateni, Cyrus P+5 more
core
Optimizing management of ruxolitinib in patients with myelofibrosis: the need for individualized dosing [PDF]
Ruxolitinib, an oral JAK1 and JAK2 inhibitor, is approved in the US for patients with intermediate or high-risk myelofibrosis (MF), a chronic neoplasm associated with aberrant myeloproliferation, progressive bone marrow fibrosis, splenomegaly, and ...
Jorge Cortes, Ruben A Mesa
core +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner+7 more
wiley +1 more source
CLINICAL AND PATHOMORPHOLOGICAL EXAMINATION OF MYELOFIBROSIS IN CHRONIC MYELOID LEUKEMIA
Pathomorphology study of marrow fibrosis in patients with chronic myeloid leukemia was carried out using morphometric image analysis software. It was revealed that every second patient had myelofibrosis.
T. Yu. Dolgikh+3 more
doaj