Results 191 to 200 of about 426,237 (354)
Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert+3 more
wiley +1 more source
Features of the molecular expression of alkaline phosphatase gene in chronic myeloid leukemia
L. P. Shvachko+2 more
openalex +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar+2 more
wiley +1 more source
Acute myeloid leukemia complicated with tuberculosis.
Keiko Morikawa, Yoko Niki, H Hoshizaki
openalex +2 more sources
DNA aneuploidies in adult patients with acute myeloid leukemia. Incidence and relation to patient characteristics and morphologic subtypes [PDF]
Wolfgang Hiddemann+3 more
openalex +1 more source
What's New? About half of penile squamous cell carcinomas are causally associated with inflammatory conditions such as lichen sclerosus (LSc), but few large‐scale studies have assessed the risk of penile cancer in men with LSc. Here, the authors conducted a large nationwide study in Denmark to estimate the risk of penile and non‐penile cancer in men ...
Marianne Gardar Stærk+5 more
wiley +1 more source
AKI in chronic myeloid leukemia: remember lysozyme-induced nephropathy. [PDF]
Santos A, Marques N, Pestana R.
europepmc +1 more source
What's New? Poor prognosis in cholangiocarcinoma (CCA) is attributed to late diagnosis and intrinsic chemoresistance. In particular, resistance mechanisms that suppress apoptosis limit the effectiveness of gemcitabine‐based regimens, which remain the standard treatment.
Wunan Mi+7 more
wiley +1 more source