Results 191 to 200 of about 1,006,148 (403)

Allogeneic Hematopoietic Stem Cell Transplantation for Children and Adolescents with Acute Myeloid Leukemia in Brazil: A Multicentric Retrospective Study [PDF]

open access: gold, 2020
Ana Luiza Rodrigues   +15 more
openalex   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo   +6 more
wiley   +1 more source

Myeloid Sarcoma of the Paranasal Sinuses in a Patient with Acute Myeloid Leukemia

open access: diamond, 2018
Jun Suzuki   +6 more
openalex   +2 more sources

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

open access: yesAdvanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo   +5 more
wiley   +1 more source

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

open access: yesNew England Journal of Medicine, 2017
R. Stone   +28 more
semanticscholar   +1 more source

Induction of apoptosis and differentiation by Na/H exchanger 1 modulation in acute myeloid leukemia cells

open access: green, 2019
Shin Young Hyun   +10 more
openalex   +2 more sources

An unusual presentation of disseminated cysticercosis in a child with chronic myeloid leukemia

open access: gold, 2020
Sneha Tandon   +3 more
openalex   +1 more source

CXC Chemokine‐Driven Vascular Reprogramming: Modulating Tumor Vasculature to Boost Therapeutic Response

open access: yesAdvanced Science, EarlyView.
Tumor vascular remodeling is discussed from a chemokine‐centered perspective. This review summarizes the bidirectional, temporal, and tissue‐specific roles of CXC chemokines in regulating vascular function and immune accessibility. A functional vascular normalization score is introduced as a conceptual framework to integrate dynamic vascular and immune
Hongdan Chen   +7 more
wiley   +1 more source

Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies [PDF]

open access: yes, 2017
Allegra A. Petti   +21 more
core   +2 more sources

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