Results 171 to 180 of about 232,812 (303)
Mosaic chromosomal alterations and relation to haematological cancer in two large Danish cohorts
Summary Mosaic chromosomal alterations (mCAs) are large somatic gains, losses and copy‐neutral loss of heterozygosity identified in the peripheral blood, which represent a relatively unexplored spectrum of clonal haematopoiesis. We aimed to describe mCAs in two large Danish cohorts with extensive long‐term registry‐based follow‐up and examine ...
Cecilie Velsoe Maeng +23 more
wiley +1 more source
Exploring the psychological impact and healthcare experiences of patients living with <b>triple class refractory multiple myeloma:</b> an interpretative phenomenological analysis study. [PDF]
Ali N +4 more
europepmc +1 more source
In patients with lenalidomide‐refractory multiple myeloma from the BOSTON trial subgroup analysis,1 selinexor (SEL) dose reduction versus full dosing substantially improved efficacy outcomes, including higher overall response rate (74.3% vs. 55.6%), deeper responses (≥ very good partial response: 48.6% vs.
Muhamed Baljevic
wiley +1 more source
CD47 promotes myeloma cell growth through JAK–STAT3/MYC signalling and is targetable by ruxolitinib
Summary Cluster of differentiation 47 (CD47), a ‘don't eat me’ immune checkpoint receptor, is frequently overexpressed on multiple myeloma (MM) cells and contributes to immune evasion. While its immune regulatory function is well established, the intrinsic oncogenic role of CD47 remains poorly understood.
Omar Faruq +6 more
wiley +1 more source
Hyperviscosity Syndrome as a Rare Presentation of Immunoglobulin G Kappa Smoldering Multiple Myeloma Successfully Treated With Daratumumab. [PDF]
Idamakanti M +3 more
europepmc +1 more source
Summary Young adults (YA) are particularly affected by comorbid conditions following allogeneic haematopoietic stem cell transplantation (alloHSCT), as they have to live with them for many years. This is the first multicentre prospective study investigating sequelae after alloHSCT in YA in Germany. In total, 107 patients who survived relapse‐free until
Pauline Rocke +9 more
wiley +1 more source
Giant expansile humeral lesion with soap-bubble appearance mimicking a primary bone tumor: Multiple myeloma as the final diagnosis. [PDF]
Khor ZX.
europepmc +1 more source

