Results 221 to 230 of about 382,920 (355)

Differential expression of immune activation markers in T cells from patients with multiple myeloma. [PDF]

Front Oncol
Lin J, Zhang X, Zhao Y, Luo L, Yuan H, Zhong L.   +5 more
europepmc   +1 more source

Updated survival analysis of a randomized phase III study of subcutaneous versus intravenous bortezomib in patients with relapsed multiple myeloma

, 2012
Bertrand Arnulf, Halyna Pylypenko, Sebastian Grosicki, Ievgenii Karamanesht, Xavier Leleu, Helgi van de Velde, H. Feng, Andrew Cakana, William Deraedt, Philippe Moreau   +9 more
openalex   +2 more sources

Elective Surgical Care Pathways Are Associated With Lower Fracture Rates at Presentation and Contribute to Superior Clinical Outcomes in Metastatic Bone Disease

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Metastatic bone disease (MBD) often necessitates orthopaedic surgical intervention, which occurs through either emergent or elective care pathways. This study compared post‐operative outcomes between patients undergoing elective versus emergent surgery for MBD involving the pelvis and appendicular skeleton. Methods We
Annalise G Abbott, Joseph K. Kendal, Benjamin Wajda, Golpira Elmi Assadzadeh, Shannon K. T. Puloski, Michael J. Monument   +5 more
wiley   +1 more source

Improved survival in multiple myeloma and the impact of novel therapies.

Blood, 2008
Shaji K. Kumar, S. Rajkumar, A. Dispenzieri, M. Lacy, S. Hayman, F. Buadi, S. Zeldenrust, D. Dingli, S. Russell, J. Lust, P. Greipp, R. Kyle, M. Gertz   +12 more
semanticscholar   +1 more source

Deresuscitation Informed by Ultrasound in Patients with Septic Shock Trial

Journal of Ultrasound in Medicine, EarlyView.
Objectives The venous excess ultrasound (VExUS) can be used at the point‐of‐care to identify venous overload and end‐organ congestion in an effort to individually tailor resuscitation and deresuscitation in patients with septic shock. Methods We conducted a pilot randomized controlled feasibility trial of VExUS‐guided fluid management in adult patients
Brendan Innes, Christopher Allison, Nicholas Seidler, Burton Shen, Andrew Fried, Gary Phillips, Andrew Levinson, Adeel Abbasi   +7 more
wiley   +1 more source

Bortezomib or high-dose dexamethasone for relapsed multiple myeloma.

New England Journal of Medicine, 2005
P. Richardson, P. Sonneveld, M. Schuster, D. Irwin, E. Stadtmauer, T. Facon, J. Harousseau, D. Ben-yehuda, S. Lonial, H. Goldschmidt, D. Reece, J. San-Miguel, J. Bladé, M. Boccadoro, J. Cavenagh, W. Dalton, A. Boral, D. Esseltine, Jane Porter, D. Schenkein, K. Anderson   +20 more
semanticscholar   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Assessment of Treatment Response in Patients With Scleromyxedema by the Double Modified Rodnan Skin Score

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Scleromyxedema (SMX) is a cutaneous mucinosis characterised by an abnormal accumulation of mucin in the skin and limited treatment options. Assessment of therapy response during treatment is challenging. Objectives Patients with SMX receiving high‐dose intravenous IVIg therapy were included to assess validity of the double modified ...
Julia K. Winkler, Alexander H. Enk
wiley   +1 more source

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu, Jin‐Hao Chen, Yan‐Fang Wang, Xiao Wu, Hui‐Yun Ni, Qiu‐Rong Zhang   +5 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source